5DYY
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![BU of 5dyy by Molmil](/molmil-images/mine/5dyy) | Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Coquelle, N, Brus, B, Colletier, J.P. | 登録日 | 2015-09-25 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Development of an in-vivo active reversible butyrylcholinesterase inhibitor. Sci Rep, 6, 2016
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3U4A
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![BU of 3u4a by Molmil](/molmil-images/mine/3u4a) | From soil to structure: a novel dimeric family 3-beta-glucosidase isolated from compost using metagenomic analysis | 分子名称: | CALCIUM ION, JMB19063, beta-D-glucopyranose, ... | 著者 | McAndrew, R.P, Park, J.I, Reindl, W, Friedland, G.D, D'haeseleer, P, Northen, T, Sale, K.L, Simmons, B.A, Adams, P.D. | 登録日 | 2011-10-07 | 公開日 | 2013-04-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | From soil to structure: a novel dimeric family 3-beta--glucosidase isolated from compost using metagenomic analysis To be Published
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6GRP
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![BU of 6grp by Molmil](/molmil-images/mine/6grp) | Crystal Structure Of Human Transthyretin in complex with 3,5,6-trichloro-2-pyridinol (TC2P) | 分子名称: | 3,5,6-trichloro-2-pyridinol, SODIUM ION, Transthyretin | 著者 | Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. | 登録日 | 2018-06-12 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52, 2018
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2XFE
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![BU of 2xfe by Molmil](/molmil-images/mine/2xfe) | vCBM60 in complex with galactobiose | 分子名称: | CALCIUM ION, CARBOHYDRATE BINDING MODULE, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose | 著者 | Montanier, C, Flint, J.E, Bolam, D.N, Xie, H, Liu, Z, Rogowski, A, Weiner, D.P, Nurizzo, D, Roberts, S.M, Turkenburg, J.P, Davies, G.J, Gilbert, H.J. | 登録日 | 2010-05-21 | 公開日 | 2010-06-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-Dependent Carbohydrate Binding Modules. J.Biol.Chem., 285, 2010
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5DOW
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6GEZ
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![BU of 6gez by Molmil](/molmil-images/mine/6gez) | THE STRUCTURE OF TWITCH-2B N532F | 分子名称: | CALCIUM ION, FORMIC ACID, Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein | 著者 | Trigo Mourino, P, Paulat, M, Thestrup, T, Griesbeck, O, Griesinger, C, Becker, S. | 登録日 | 2018-04-27 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Dynamic tuning of FRET in a green fluorescent protein biosensor. Sci Adv, 5, 2019
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2XFK
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![BU of 2xfk by Molmil](/molmil-images/mine/2xfk) | Human BACE-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(ethylamino)-5-((methylsulfonyl)(phenyl)amino)benzamide | 分子名称: | BETA-SECRETASE 1, N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1--METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(ETHYLAMINO)-5-((METHYLSULFONYL)(PHENYL)AMINO)BENZAMIDE | 著者 | Clarke, B, Cutler, L, Demont, E, Dingwall, C, Dunsdon, R, Hawkins, J, Howes, C, Hussain, I, Maile, G, Matico, R, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | 登録日 | 2010-05-24 | 公開日 | 2010-07-07 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Bace-1 Inhibitors Using Novel Edge-to-Face Interaction with Arg-296 Bioorg.Med.Chem.Lett., 20, 2010
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4GWL
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![BU of 4gwl by Molmil](/molmil-images/mine/4gwl) | Structure of three phase partition treated lipase from Thermomyces lanuginosa at 2.55A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase | 著者 | Shukla, P.K, Sinha, M, Mukherjee, J, Gupta, M.N, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2012-09-03 | 公開日 | 2012-09-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of three phase partition treated lipase from Thermomyces lanuginosa at 2.55A resolution To be Published
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5JP4
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8EFS
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![BU of 8efs by Molmil](/molmil-images/mine/8efs) | CryoEM of the soluble OPA1 tetramer from the apo helical assembly on a lipid membrane | 分子名称: | Dynamin-like 120 kDa protein, form S1 | 著者 | Nyenhuis, S.B, Wu, X, Stanton, A.E, Strub, M.P, Yim, Y.I, Canagarajah, B, Hinshaw, J.E. | 登録日 | 2022-09-09 | 公開日 | 2023-06-28 | 最終更新日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (9.68 Å) | 主引用文献 | OPA1 helical structures give perspective to mitochondrial dysfunction. Nature, 620, 2023
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7UNA
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![BU of 7una by Molmil](/molmil-images/mine/7una) | SfSTING with cGAMP (masked) | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CD-NTase-associated protein 12 | 著者 | Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J. | 登録日 | 2022-04-09 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structure of an active bacterial TIR-STING filament complex. Nature, 608, 2022
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1A35
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![BU of 1a35 by Molmil](/molmil-images/mine/1a35) | HUMAN TOPOISOMERASE I/DNA COMPLEX | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*(BRU)P*(BRU)P*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*+UP*+UP*+UP*+UP*CP*+UP*AP*AP*GP*TP*CP*TP*TP*TP*+ UP*T)-3'), PROTEIN (DNA TOPOISOMERASE I) | 著者 | Redinbo, M.R, Stewart, L, Kuhn, P, Champoux, J.J, Hol, W.G. | 登録日 | 1998-01-29 | 公開日 | 1998-08-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279, 1998
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8EEW
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![BU of 8eew by Molmil](/molmil-images/mine/8eew) | CryoEM of the soluble OPA1 dimer from the GDP-AlFx bound helical assembly on a lipid membrane | 分子名称: | Dynamin-like 120 kDa protein, form S1, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Nyenhuis, S.B, Wu, X, Stanton, A.E, Strub, M.P, Yim, Y.I, Canagarajah, B, Hinshaw, J.E. | 登録日 | 2022-09-07 | 公開日 | 2023-06-28 | 最終更新日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (5.48 Å) | 主引用文献 | OPA1 helical structures give perspective to mitochondrial dysfunction. Nature, 620, 2023
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7F03
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![BU of 7f03 by Molmil](/molmil-images/mine/7f03) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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8EF7
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![BU of 8ef7 by Molmil](/molmil-images/mine/8ef7) | CryoEM of the soluble OPA1 dimer from the apo helical assembly on a lipid membrane | 分子名称: | Dynamin-like 120 kDa protein, form S1 | 著者 | Nyenhuis, S.B, Wu, X, Stanton, A.E, Strub, M.P, Yim, Y.I, Canagarajah, B, Hinshaw, J.E. | 登録日 | 2022-09-08 | 公開日 | 2023-06-28 | 最終更新日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (9.68 Å) | 主引用文献 | OPA1 helical structures give perspective to mitochondrial dysfunction. Nature, 620, 2023
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7F04
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![BU of 7f04 by Molmil](/molmil-images/mine/7f04) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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2HA7
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![BU of 2ha7 by Molmil](/molmil-images/mine/2ha7) | Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with butyrylthiocholine | 分子名称: | 2-(BUTYRYLSULFANYL)-N,N,N-TRIMETHYLETHANAMINIUM, 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, Acetylcholinesterase, ... | 著者 | Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P. | 登録日 | 2006-06-12 | 公開日 | 2006-07-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281, 2006
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3PAL
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![BU of 3pal by Molmil](/molmil-images/mine/3pal) | IONIC INTERACTIONS WITH PARVALBUMINS. CRYSTAL STRUCTURE DETERMINATION OF PIKE 4.10 PARVALBUMIN IN FOUR DIFFERENT IONIC ENVIRONMENTS | 分子名称: | CALCIUM ION, MAGNESIUM ION, PARVALBUMIN | 著者 | Declercq, J.P, Tinant, B, Parello, J, Rambaud, J. | 登録日 | 1990-11-08 | 公開日 | 1992-01-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ionic interactions with parvalbumins. Crystal structure determination of pike 4.10 parvalbumin in four different ionic environments. J.Mol.Biol., 220, 1991
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4ENR
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![BU of 4enr by Molmil](/molmil-images/mine/4enr) | Structure of E530I variant E. coli KatE | 分子名称: | Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Loewen, P.C, Jha, V. | 登録日 | 2012-04-13 | 公開日 | 2012-05-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli. Arch.Biochem.Biophys., 526, 2012
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4AOB
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![BU of 4aob by Molmil](/molmil-images/mine/4aob) | SAM-I riboswitch containing the T. solenopsae Kt-23 in complex with S- adenosyl methionine | 分子名称: | BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ... | 著者 | Schroeder, K.T, Daldrop, P, McPhee, S.A, Lilley, D.M.J. | 登録日 | 2012-03-25 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure and Folding of a Rare, Natural Kink Turn in RNA with an Aa Pair at the 2B2N Position. RNA, 18, 2012
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6GNO
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![BU of 6gno by Molmil](/molmil-images/mine/6gno) | Crystal Structure Of Sea Bream Transthyretin in complex with Tetrabromobisphenol A (TBBPA) | 分子名称: | 4,4'-propane-2,2-diylbis(2,6-dibromophenol), SULFATE ION, Transthyretin | 著者 | Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. | 登録日 | 2018-05-31 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52, 2018
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3HD4
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![BU of 3hd4 by Molmil](/molmil-images/mine/3hd4) | MHV Nucleocapsid Protein NTD | 分子名称: | Nucleoprotein | 著者 | Giedroc, D.P, Keane, S.C, Dann III, C.E. | 登録日 | 2009-05-06 | 公開日 | 2009-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Coronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA Duplexes. J.Mol.Biol., 394, 2009
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2CLX
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![BU of 2clx by Molmil](/molmil-images/mine/2clx) | 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects | 分子名称: | 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, CELL DIVISION PROTEIN KINASE 2 | 著者 | Krystof, V, Cankar, P, Frysova, I, Slouka, J, Kontopidis, G, Dzubak, P, Hajduch, M, Deazevedo, W.F, Paprskarova, M, Orsag, M, Rolcik, J, Latr, A, Fischer, P.M, Strnad, M. | 登録日 | 2006-05-02 | 公開日 | 2006-11-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 4-Arylazo-3,5-Diamino-1H-Pyrazole Cdk Inhibitors: Sar Study, Crystal Structure in Complex with Cdk2, Selectivity, and Cellular Effects J.Med.Chem., 49, 2006
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5EAR
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![BU of 5ear by Molmil](/molmil-images/mine/5ear) | Crystal structure of human WDR5 in complex with compound 9d | 分子名称: | 1,2-ETHANEDIOL, N-[5-(2,3-dihydro-1-benzofuran-7-yl)-2-(4-methylpiperazin-1-yl)phenyl]-3-methylbenzamide, SULFATE ION, ... | 著者 | DONG, A, DOMBROVSKI, L, SMIL, D, GETLIK, M, BOLSHAN, Y, WALKER, J.R, SENISTERRA, G, PODA, G, AL-AWAR, R, SCHAPIRA, M, VEDADI, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | 登録日 | 2015-10-16 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1). J. Med. Chem., 59, 2016
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1Y6T
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![BU of 1y6t by Molmil](/molmil-images/mine/1y6t) | HIV-1 Dis(Mal) Duplex Co Hexamine-Soaked | 分子名称: | 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', COBALT (III) ION, SODIUM ION | 著者 | Ennifar, E, Walter, P, Dumas, P. | 登録日 | 2004-12-07 | 公開日 | 2004-12-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes Nucleic Acids Res., 31, 2003
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