5A0V
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![BU of 5a0v by Molmil](/molmil-images/mine/5a0v) | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | 分子名称: | 5'-R(*CP*GP*CP*CP*UP*CP)-3', CYTIDINE-5'-MONOPHOSPHATE, RIBONUCLEASE J, ... | 著者 | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | 登録日 | 2015-04-23 | 公開日 | 2015-08-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J Nucleic Acids Res., 43, 2015
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4MS5
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![BU of 4ms5 by Molmil](/molmil-images/mine/4ms5) | Lambda-[Ru(TAP)2(dppz-11,12-(F)2)]2+ bound to CCGGATCCGG | 分子名称: | (11,12-difluorodipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium(2+), BARIUM ION, DNA | 著者 | Hall, J.P, Cardin, C.J. | 登録日 | 2013-09-18 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | The effects of disubstitution on the binding of ruthenium complexes to DNA Thesis, University of Reading, 2014
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3SAE
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![BU of 3sae by Molmil](/molmil-images/mine/3sae) | Structure of a three-domain sesquiterpene synthase: a prospective target for advanced biofuels production | 分子名称: | Alpha-bisabolene synthase, CHLORIDE ION, GLYCEROL, ... | 著者 | McAndrew, R.P, Peralta-Yahya, P.P, DeGiovanni, A, Pereira, J.H, Hadi, M.Z, Keasling, J.D, Adams, P.D. | 登録日 | 2011-06-02 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure of a three-domain sesquiterpene synthase: a prospective target for advanced biofuels production. Structure, 19, 2011
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8OFQ
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![BU of 8ofq by Molmil](/molmil-images/mine/8ofq) | Human adenovirus type 25 fiber-knob protein | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber, ... | 著者 | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | 登録日 | 2023-03-16 | 公開日 | 2023-09-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Broad sialic acid usage amongst species D human adenovirus. Npj Viruses, 1, 2023
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4GCR
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![BU of 4gcr by Molmil](/molmil-images/mine/4gcr) | STRUCTURE OF THE BOVINE EYE LENS PROTEIN GAMMA-B (GAMMA-II)-CRYSTALLIN AT 1.47 ANGSTROMS | 分子名称: | GAMMA-B CRYSTALLIN | 著者 | Slingsby, C, Najmudin, S, Nalini, V, Driessen, H.P.C, Blundell, T.L, Moss, D.S, Lindley, P. | 登録日 | 1992-04-02 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structure of the bovine eye lens protein gammaB(gammaII)-crystallin at 1.47 A. Acta Crystallogr.,Sect.D, 49, 1993
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6V8X
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![BU of 6v8x by Molmil](/molmil-images/mine/6v8x) | VRC01 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Henderson, R, Acharya, P. | 登録日 | 2019-12-12 | 公開日 | 2020-02-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. Nat Commun, 11, 2020
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6FES
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![BU of 6fes by Molmil](/molmil-images/mine/6fes) | Crystal structure of novel repeat protein BRIC2 fused to DARPin D12 | 分子名称: | 1,2-ETHANEDIOL, D12_BRIC2, a synthetic protein,D12_BRIC2, ... | 著者 | ElGamacy, M, Coles, M, Ernst, P, Zhu, H, Hartmann, M.D, Plueckthun, A, Lupas, A. | 登録日 | 2018-01-03 | 公開日 | 2018-09-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture. ACS Synth Biol, 7, 2018
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2WIH
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![BU of 2wih by Molmil](/molmil-images/mine/2wih) | STRUCTURE OF CDK2-CYCLIN A WITH PHA-848125 | 分子名称: | CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2, N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE, ... | 著者 | Brasca, M.G, Amboldi, N, Ballinari, D, Cameron, A.D, Casale, E, Cervi, G, Colombo, M, Colotta, F, Croci, V, Dalessio, R, Fiorentini, F, Isacchi, A, Mercurio, C, Moretti, W, Panzeri, A, Pastori, W, Pevarello, P, Quartieri, F, Roletto, F, Traquandi, G, Vianello, P, Vulpetti, A, Ciomei, M. | 登録日 | 2009-05-13 | 公開日 | 2009-07-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification of N,1,4,4-Tetramethyl-8-{[4-(4-Methylpiperazin-1-Yl)Phenyl]Amino}-4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline-3-Carboxamide (Pha-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor. J.Med.Chem., 52, 2009
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6SZ2
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![BU of 6sz2 by Molmil](/molmil-images/mine/6sz2) | Crystal structure of YTHDC1 with fragment 3 (DHU_DC1_149) | 分子名称: | SULFATE ION, YTH domain-containing protein 1, ~{N}-methyl-1,6-naphthyridin-4-amine | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | 登録日 | 2019-10-01 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
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6PUV
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![BU of 6puv by Molmil](/molmil-images/mine/6puv) | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin | 分子名称: | C-type lectin domain family 10 member A, CALCIUM ION | 著者 | Birrane, G, Murphy, P.V, Gabba, A, Luz, J.G. | 登録日 | 2019-07-18 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen. Biochemistry, 60, 2021
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4CE7
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![BU of 4ce7 by Molmil](/molmil-images/mine/4ce7) | Crystal structure of a novel unsaturated beta-glucuronyl hydrolase enzyme, belonging to family GH105, involved in ulvan degradation | 分子名称: | NITRATE ION, UNSATURATED 3S-RHAMNOGLYCURONYL HYDROLASE | 著者 | Nyvall Collen, P, Jeudy, A, Groisillier, A, Coutinho, P.M, Helbert, W, Czjzek, M. | 登録日 | 2013-11-09 | 公開日 | 2014-01-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Novel Unsaturated Beta-Glucuronyl Hydrolase Involved in Ulvan Degradation Unveils the Versatility of Stereochemistry Requirements in Family Gh105. J.Biol.Chem., 289, 2014
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3ZWT
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![BU of 3zwt by Molmil](/molmil-images/mine/3zwt) | Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor | 分子名称: | 2-{[(2,5-DICHLOROPHENYL)METHYL]SULFANYL}-5-ETHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-OL, ACETATE ION, CHLORIDE ION, ... | 著者 | Acklam, P.A, Parsons, M.R. | 登録日 | 2011-08-02 | 公開日 | 2012-06-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases. J.Med.Chem., 55, 2012
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8OFU
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![BU of 8ofu by Molmil](/molmil-images/mine/8ofu) | Human adenovirus type 53 fiber-knob protein | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber protein, ... | 著者 | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | 登録日 | 2023-03-16 | 公開日 | 2023-09-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Broad sialic acid usage amongst species D human adenovirus. Npj Viruses, 1, 2023
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4BSD
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![BU of 4bsd by Molmil](/molmil-images/mine/4bsd) | Human H7N9 Influenza Virus Haemagglutinin (with Asn-133 Glycosylation) in Complex with Avian Receptor Analogue 3'-SLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ... | 著者 | Xiong, X, Haire, L.F, Martin, S.R, Wharton, S.A, Daniels, R.S, Bennett, M.S, McCauley, J.W, Collins, P.J, Walker, P.A, Skehel, J.J, Gamblin, S.J. | 登録日 | 2013-06-10 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Receptor Binding by an H7N9 Influenza Virus from Humans Nature, 499, 2013
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7U2R
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![BU of 7u2r by Molmil](/molmil-images/mine/7u2r) | Structure of Paenibacillus sp. J14 Apyc1 | 分子名称: | Apyc1, ZINC ION | 著者 | Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J. | 登録日 | 2022-02-24 | 公開日 | 2022-04-20 | 最終更新日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. Nature, 605, 2022
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7BTO
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![BU of 7bto by Molmil](/molmil-images/mine/7bto) | EcoR124I-ArdA in the Translocation State | 分子名称: | Antirestriction protein ArdA, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | 著者 | Gao, Y, Gao, P. | 登録日 | 2020-04-02 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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8JSM
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![BU of 8jsm by Molmil](/molmil-images/mine/8jsm) | The structure of EBOV L-VP35-RNA complex (conformation 1) | 分子名称: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome., ... | 著者 | Qi, P, Yi, S. | 登録日 | 2023-06-20 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
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8JSL
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![BU of 8jsl by Molmil](/molmil-images/mine/8jsl) | The structure of EBOV L-VP35-RNA complex | 分子名称: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV, ... | 著者 | Qi, P, Yi, S. | 登録日 | 2023-06-20 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
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7U2S
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![BU of 7u2s by Molmil](/molmil-images/mine/7u2s) | Structure of Paenibacillus xerothermodurans Apyc1 in the apo state | 分子名称: | Apyc1, ZINC ION | 著者 | Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J. | 登録日 | 2022-02-24 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. Nature, 605, 2022
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7BVY
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![BU of 7bvy by Molmil](/molmil-images/mine/7bvy) | |
8JSN
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![BU of 8jsn by Molmil](/molmil-images/mine/8jsn) | The structure of EBOV L-VP35-RNA complex (conformation 2) | 分子名称: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome, ... | 著者 | Qi, P, Yi, S. | 登録日 | 2023-06-20 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
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2IVT
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6SZM
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![BU of 6szm by Molmil](/molmil-images/mine/6szm) | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2009 | 分子名称: | 1,2-ETHANEDIOL, 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine, AMMONIUM ION, ... | 著者 | Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2019-10-02 | 公開日 | 2019-10-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma. J.Med.Chem., 63, 2020
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6T08
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![BU of 6t08 by Molmil](/molmil-images/mine/6t08) | Crystal structure of YTHDC1 with fragment 21 (DHU_DC1_131) | 分子名称: | SULFATE ION, YTHDC1, ~{N}-(1~{H}-imidazol-2-yl)thiophene-2-sulfonamide | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | 登録日 | 2019-10-02 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
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6QF1
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![BU of 6qf1 by Molmil](/molmil-images/mine/6qf1) | X-Ray structure of Proteinase K crystallized on a silicon chip | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Proteinase K | 著者 | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | 登録日 | 2019-01-09 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.737 Å) | 主引用文献 | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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