4LQR
 
 | | Structure of CBM32-3 from a family 31 glycoside hydrolase from Clostridium perfringens | | 分子名称: | CALCIUM ION, Glycosyl hydrolase, family 31/fibronectin type III domain protein | | 著者 | Grondin, J.M, Furness, H.S, Duan, D, Spencer, C.A, Allingham, J.S, Smith, S.P. | | 登録日 | 2013-07-19 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens.
Plos One, 12, 2017
|
|
6YIJ
 | | Crystal structure of the CREBBP bromodomain in complex with a benzo-diazepine ligand | | 分子名称: | (4~{R})-6-[(~{E})-5-(7-methoxy-3,4-dihydro-2~{H}-quinolin-1-yl)pent-1-enyl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one, CREBBP | | 著者 | Picaud, S, Brand, M, Tobias, K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Conway, S, Filippakopoulos, P. | | 登録日 | 2020-04-01 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the CREBBP bromodomain in complex with a benzo-diazepine ligand
To Be Published
|
|
6TI1
 | | SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/L-Threonine/Lys230 gem diamine complex | | 分子名称: | GLYCEROL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ... | | 著者 | Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I. | | 登録日 | 2019-11-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus
To Be Published
|
|
6ACS
 | | poly-cis-prenyltransferase | | 分子名称: | CITRIC ACID, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), GLYCEROL, ... | | 著者 | Ko, T.-P, Chen, Y. | | 登録日 | 2018-07-27 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structure of undecaprenyl pyrophosphate synthase from Acinetobacter baumannii
Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
6GR7
 | | Crystal Structure Of Human Transthyretin in complex with 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) | | 分子名称: | 2-[2,4,5-tris(chloranyl)phenoxy]ethanoic acid, Transthyretin | | 著者 | Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. | | 登録日 | 2018-06-09 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ. Sci. Technol., 52, 2018
|
|
6T5J
 | | Structure of NUDT15 in complex with inhibitor TH1760 | | 分子名称: | 6-[4-(1~{H}-indol-5-ylcarbonyl)piperazin-1-yl]sulfonyl-3~{H}-1,3-benzoxazol-2-one, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Carter, M, Rehling, D, Desroses, M, Zhang, S.M, Hagenkort, A, Valerie, N.C.K, Helleday, T, Stenmark, P. | | 登録日 | 2019-10-16 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Development of a chemical probe against NUDT15.
Nat.Chem.Biol., 16, 2020
|
|
6AIP
 | | Cab2 mutant-H337A complex with phosphopantothenoylcystine | | 分子名称: | (5R,12R,17R)-17-amino-12-carboxy-1,1,5-trihydroxy-4,4-dimethyl-6,10-dioxo-2-oxa-14,15-dithia-7,11-diaza-1-phosphaoctadecan-18-oic acid 1-oxide (non-preferred name), Phosphopantothenate--cysteine ligase CAB2 | | 著者 | Zheng, P, Zhu, Z. | | 登録日 | 2018-08-24 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.
J. Mol. Biol., 431, 2019
|
|
4MEW
 | | Structure of the core fragment of human PR70 | | 分子名称: | CALCIUM ION, GLYCEROL, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta | | 著者 | Dovega, R.B, Quistgaard, E.M, Tsutakawa, S, Anandapadamanaban, M, Low, C, Nordlund, P. | | 登録日 | 2013-08-27 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.993 Å) | | 主引用文献 | Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A.
Plos One, 9, 2014
|
|
4OKC
 | | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis | | 分子名称: | LysM domain protein | | 著者 | Patra, D, Mishra, P, Surolia, A, Vijayan, M. | | 登録日 | 2014-01-22 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis.
Glycobiology, 24, 2014
|
|
6TTW
 | | Crystal structure of the human METTL3-METTL14 complex bound to Compound 4 (ASI_M3M_047) | | 分子名称: | (2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)-~{N}-piperidin-4-yl-oxolane-2-carboxamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... | | 著者 | Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. | | 登録日 | 2019-12-30 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Small-Molecule Inhibitors of METTL3, the Major Human Epitranscriptomic Writer.
Chemmedchem, 15, 2020
|
|
6YHR
 | | Crystal structure of Werner syndrome helicase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Werner syndrome ATP-dependent helicase, ZINC ION | | 著者 | Newman, J.A, Gavard, A.E, Savitsky, P, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2020-03-30 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the helicase core of Werner helicase, a key target in microsatellite instability cancers.
Life Sci Alliance, 4, 2021
|
|
3II3
 | | Structure of ORF157 from Acidianus filamentous Virus 1 | | 分子名称: | GLYCEROL, NICKEL (II) ION, Putative uncharacterized protein | | 著者 | Goulet, A, Redder, P, Pina, M, Prangishvili, D, van Tilbeurgh, H, Cambillau, C, Campanacci, V. | | 登録日 | 2009-07-31 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | ORF157 from the archaeal virus Acidianus filamentous virus 1 defines a new class of nuclease
J.Virol., 84, 2010
|
|
6YRW
 | | SHMT from Streptococcus thermophilus Tyr55Ser variant as internal aldimine and as non-covalent complex with D-Ser | | 分子名称: | D-SERINE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I. | | 登録日 | 2020-04-20 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus
To Be Published
|
|
1CIS
 | |
4M3E
 | | Rapid and efficient design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging and linking approaches | | 分子名称: | 4-(2-{[(propylsulfonyl)amino]methyl}-1,3-thiazol-4-yl)-N-(3,3,3-trifluoropropyl)benzamide, HTH-type transcriptional regulator EthR | | 著者 | Villemagne, B, Flipo, M, Blondiaux, N, Crauste, C, Malaquin, S, Leroux, F, Piveteau, C, Villeret, V, Brodin, P, Villoutreix, B, Sperandio, O, Wohlkonig, A, Wintjens, R, Deprez, B, Baulard, A, Willand, N. | | 登録日 | 2013-08-06 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.109 Å) | | 主引用文献 | Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches.
J.Med.Chem., 57, 2014
|
|
4MA7
 | | Crystal structure of mouse prion protein complexed with Promazine | | 分子名称: | Major prion protein, POM1 heavy chain, POM1 light chain, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2013-08-15 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
|
|
4MAI
 | | Structure of Aspergillus oryzae AA11 Lytic Polysaccharide Monooxygenase with Cu(I) | | 分子名称: | 1,2-ETHANEDIOL, AA11 Lytic Polysaccharide Monooxygenase, CHLORIDE ION, ... | | 著者 | Hemsworth, G.R, Henrissat, B, Walton, P.H, Davies, G.J. | | 登録日 | 2013-08-16 | | 公開日 | 2013-12-18 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Discovery and characterization of a new family of lytic polysaccharide monooxygenases.
Nat.Chem.Biol., 10, 2014
|
|
3I86
 | | Crystal structure of the P60 Domain from M. avium subspecies paratuberculosis antigen MAP1204 | | 分子名称: | ISOPROPYL ALCOHOL, Putative uncharacterized protein | | 著者 | Ramyar, K.X, Lingle, C.K, McWhorter, W.J, Bouyain, S, Bannantine, J.P, Geisbrecht, B.V. | | 登録日 | 2009-07-09 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Atypical structural features of two P60 family members from Mycobacterium avium subspecies paratuberculosis
To be Published
|
|
6YNE
 | | GAPDH purified from the supernatant of HEK293F cells: crystal form 2 of 4. | | 分子名称: | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Glyceraldehyde-3-phosphate dehydrogenase | | 著者 | Roversi, P, Lia, A. | | 登録日 | 2020-04-13 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.853 Å) | | 主引用文献 | Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid.
Wellcome Open Res, 5, 2020
|
|
4MDR
 | | Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, in complex with a sorting peptide from the amyloid precursor protein (APP) | | 分子名称: | AP-4 complex subunit mu-1, Amyloid beta A4 protein | | 著者 | Ross, B.H, Lin, Y, Corales, E.A, Burgos, P.V, Mardones, G.A. | | 登録日 | 2013-08-23 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Functional Characterization of Cargo-Binding Sites on the mu 4-Subunit of Adaptor Protein Complex 4.
Plos One, 9, 2014
|
|
4PCF
 | |
6TNF
 | | Structure of monoubiquitinated FANCD2 in complex with FANCI and DNA | | 分子名称: | DNA (33-MER), FANCD2, Fanconi anemia complementation group I, ... | | 著者 | Alcon, P, Shakeel, S, Passmore, L.A. | | 登録日 | 2019-12-07 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
|
|
6H0C
 | | Flv1 flavodiiron core from Synechocystis sp. PCC6803 | | 分子名称: | CHLORIDE ION, CITRATE ANION, Putative diflavin flavoprotein A 3 | | 著者 | Borges, P.T, Romao, C.V, Saraiva, L, Goncalves, V.L, Carrondo, M.A, Teixeira, M, Frazao, C. | | 登録日 | 2018-07-08 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.592 Å) | | 主引用文献 | Analysis of a new flavodiiron core structural arrangement in Flv1-Delta FlR protein from Synechocystis sp. PCC6803.
J. Struct. Biol., 205, 2019
|
|
4PJY
 | | Azide bound Cysteine Dioxygenase at pH 6.2 | | 分子名称: | AZIDE ION, Cysteine dioxygenase type 1, FE (III) ION | | 著者 | Driggers, C.M, Karplus, P.A. | | 登録日 | 2014-05-12 | | 公開日 | 2016-02-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.
J. Mol. Biol., 428, 2016
|
|
1JP6
 | |
