5ANL
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![BU of 5anl by Molmil](/molmil-images/mine/5anl) | Crystal structure of VPS34 in complex with (2S)-8-((3R)-3- Methylmorpholin-4-yl)-1-(3-methyl-2-oxo- butyl)-2-(trifluoromethyl)-3, 4-dihydro-2H-pyrimido(1,2-a)pyrimidin-6- one, processed with the CrystalDirect automated mounting and cryo-cooling technology | 分子名称: | (8S)-2-(morpholin-4-yl)-9-[2-(propan-2-yloxy)ethyl]-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 | 著者 | Zander, U, Hoffmann, G, Mathieu, M, Marquette, J.-P, Cornaciu, I, Cipriani, F, Marquez, J.A. | 登録日 | 2015-09-07 | 公開日 | 2016-04-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Automated Harvesting and Processing of Protein Crystals Through Laser Photoablation. Acta Crystallogr.,Sect.D, 72, 2016
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5MA6
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![BU of 5ma6 by Molmil](/molmil-images/mine/5ma6) | GFP-binding DARPin 3G124nc | 分子名称: | 1,2-ETHANEDIOL, 3G124nc, Green fluorescent protein, ... | 著者 | Hansen, S, Stueber, J, Ernst, P, Koch, A, Bojar, D, Batyuk, A, Plueckthun, A. | 登録日 | 2016-11-03 | 公開日 | 2017-12-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity. Sci Rep, 7, 2017
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5MKO
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![BU of 5mko by Molmil](/molmil-images/mine/5mko) | [2Fe-2S] cluster containing TtuA in complex with AMP. | 分子名称: | ADENOSINE MONOPHOSPHATE, FE2/S2 (INORGANIC) CLUSTER, TtuA PH0300, ... | 著者 | Arragain, S, Bimai, O, Legrand, P, Golinelli-Pimpaneau, B. | 登録日 | 2016-12-05 | 公開日 | 2017-06-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1FI2
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![BU of 1fi2 by Molmil](/molmil-images/mine/1fi2) | CRYSTAL STRUCTURE OF GERMIN (OXALATE OXIDASE) | 分子名称: | MANGANESE (II) ION, OXALATE OXIDASE | 著者 | Woo, E.J, Dunwell, J.M, Goodenough, P.W, Marvier, A.C, Pickersgill, R.W. | 登録日 | 2000-08-03 | 公開日 | 2001-05-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Germin is a manganese containing homohexamer with oxalate oxidase and superoxide dismutase activities. Nat.Struct.Biol., 7, 2000
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6B0H
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![BU of 6b0h by Molmil](/molmil-images/mine/6b0h) | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262 | 分子名称: | 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ... | 著者 | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | 登録日 | 2017-09-14 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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5F04
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![BU of 5f04 by Molmil](/molmil-images/mine/5f04) | Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 3 at 1.84A resolution | 分子名称: | 1,2-ETHANEDIOL, 3-cyclopentyl-1-[3-[4-(methylaminomethyl)phenyl]-1,3-diazinan-1-yl]propan-1-one, GLYCEROL, ... | 著者 | Surade, S, Blaszczyk, M, Nikiforov, P.O, Abell, C, Blundell, T.L. | 登録日 | 2015-11-27 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. Org.Biomol.Chem., 14, 2016
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3WCH
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![BU of 3wch by Molmil](/molmil-images/mine/3wch) | The complex structure of HsSQS wtih ligand BPH1237 | 分子名称: | Squalene synthase, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate | 著者 | Shang, N, Li, Q, Ko, T.P, Chan, H.C, Huang, C.H, Ren, F, Zheng, Y, Zhu, Z, Chen, C.C, Guo, R.T. | 登録日 | 2013-05-27 | 公開日 | 2014-06-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Squalene synthase as a target for Chagas disease therapeutics. Plos Pathog., 10, 2014
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1JAB
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![BU of 1jab by Molmil](/molmil-images/mine/1jab) | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18S | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | 登録日 | 1999-01-24 | 公開日 | 1999-04-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function. J.Biol.Chem., 274, 1999
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8D9N
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![BU of 8d9n by Molmil](/molmil-images/mine/8d9n) | CryoEM structures of bAE1 captured in multiple states. | 分子名称: | Anion exchange protein | 著者 | Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I. | 登録日 | 2022-06-10 | 公開日 | 2023-01-25 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations. Commun Biol, 5, 2022
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5TIJ
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![BU of 5tij by Molmil](/molmil-images/mine/5tij) | Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer) | 分子名称: | ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, Gamma-enolase, MAGNESIUM ION | 著者 | Leonard, P.G, Muller, F.L. | 登録日 | 2016-10-03 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.634 Å) | 主引用文献 | Eradication of ENO1-deleted Glioblastoma through Collateral Lethality Biorxiv, 2019
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6B2M
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![BU of 6b2m by Molmil](/molmil-images/mine/6b2m) | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with coenzyme A | 分子名称: | ATP-utilizing enzyme of the PP-loopsuperfamily, COENZYME A, PHOSPHATE ION | 著者 | Fellner, M, Hausinger, R.P, Hu, J. | 登録日 | 2017-09-20 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.088 Å) | 主引用文献 | Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum. Biochemistry, 57, 2018
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6EU3
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![BU of 6eu3 by Molmil](/molmil-images/mine/6eu3) | Apo RNA Polymerase III - closed conformation (cPOL3) | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A. | 登録日 | 2017-10-27 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of RNA polymerase III transcription initiation. Nature, 553, 2018
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8J8V
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![BU of 8j8v by Molmil](/molmil-images/mine/8j8v) | Structure of beta-arrestin2 in complex with D6Rpp (Local Refine) | 分子名称: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | 著者 | Maharana, J, Sarma, P, Yadav, M.K, Chami, M, Banerjee, R, Shukla, A.K. | 登録日 | 2023-05-02 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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5F7E
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![BU of 5f7e by Molmil](/molmil-images/mine/5f7e) | Crystal structure of germ-line precursor of 3BNC60 Fab | 分子名称: | Fab heavy chain, Fab light chain | 著者 | Sievers, S.A, Scharf, L, Jiang, S, Bjorkman, P.J. | 登録日 | 2015-12-08 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for germline antibody recognition of HIV-1 immunogens. Elife, 5, 2016
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6SM1
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![BU of 6sm1 by Molmil](/molmil-images/mine/6sm1) | Wild type immunoglobulin light chain (WT-1) | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Immunoglobulin lambda variable 2-14, ... | 著者 | Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J. | 登録日 | 2019-08-21 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation. Elife, 9, 2020
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5C0D
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![BU of 5c0d by Molmil](/molmil-images/mine/5c0d) | HLA-A02 carrying AQWGPDPAAA | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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5J8W
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![BU of 5j8w by Molmil](/molmil-images/mine/5j8w) | One minute iron loaded Rana Catesbeiana H' ferritin variant E57A/E136A/D140A | 分子名称: | CHLORIDE ION, FE (II) ION, Ferritin, ... | 著者 | Pozzi, C, Di Pisa, F, Mangani, S, Bernacchioni, C, Turano, P. | 登録日 | 2016-04-08 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | 主引用文献 | Ferroxidase Activity in Eukaryotic Ferritin is Controlled by Accessory-Iron-Binding Sites in the Catalytic Cavity. Chemistry, 22, 2016
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5JD3
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![BU of 5jd3 by Molmil](/molmil-images/mine/5jd3) | Crystal structure of LAE5, an alpha/beta hydrolase enzyme from the metagenome of Lake Arreo, Spain | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, LAE5, ... | 著者 | Stogios, P.J, Xu, X, Nocek, B, Cui, H, Yim, V, Martinez-Martinez, M, Alcaide, M, Ferrer, M, Savchenko, A. | 登録日 | 2016-04-15 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | To be published To Be Published
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2VFH
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![BU of 2vfh by Molmil](/molmil-images/mine/2vfh) | Crystal structure of the F96W mutant of Plasmodium falciparum triosephosphate isomerase complexed with 3-phosphoglycerate | 分子名称: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | 著者 | Gayathri, P, Banerjee, M, Vijayalakshmi, A, Balaram, H, Balaram, P, Murthy, M.R.N. | 登録日 | 2007-11-04 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65, 2009
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5C18
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5TGL
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![BU of 5tgl by Molmil](/molmil-images/mine/5tgl) | A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX | 分子名称: | LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER | 著者 | Brzozowski, A.M, Derewenda, U, Derewenda, Z.S, Dodson, G.G, Lawson, D, Turkenburg, J.P, Bjorkling, F, Huge-Jensen, B, Patkar, S.R, Thim, L. | 登録日 | 1991-10-30 | 公開日 | 1994-01-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex. Nature, 351, 1991
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8JLY
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5FBT
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![BU of 5fbt by Molmil](/molmil-images/mine/5fbt) | Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin | 分子名称: | CHLORIDE ION, Phosphoenolpyruvate synthase, Rifampin | 著者 | Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-12-14 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
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3IHL
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![BU of 3ihl by Molmil](/molmil-images/mine/3ihl) | Human CTPS2 crystal structure | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CTP synthase 2, PHOSPHATE ION | 著者 | Moche, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Kragh Nielsen, T, Nyman, T, Persson, C, Roos, A.K, Sagemark, J, Schueler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2009-07-30 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Human CTPS2 crystal structure To be Published
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6SNO
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![BU of 6sno by Molmil](/molmil-images/mine/6sno) | Crystal structures of human PGM1 isoform 2 | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, Phosphoglucomutase-1, ZINC ION | 著者 | Backe, P.H, Laerdahl, J.K, Kittelsen, L.S, Dalhus, B, Morkrid, L, Bjoras, M. | 登録日 | 2019-08-27 | 公開日 | 2020-04-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the alpha-D-phosphohexomutase superfamily. Sci Rep, 10, 2020
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