3UNY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uny by Molmil](/molmil-images/mine/3uny) | Bacillus cereus phosphopentomutase T85E variant soaked with glucose 1,6-bisphosphate | 分子名称: | GLYCEROL, MANGANESE (II) ION, Phosphopentomutase | 著者 | Iverson, T.M, Birmingham, W.R, Panosian, T.D, Nannemann, D.P, Bachmann, B.O. | 登録日 | 2011-11-16 | 公開日 | 2012-02-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular Differences between a Mutase and a Phosphatase: Investigations of the Activation Step in Bacillus cereus Phosphopentomutase. Biochemistry, 51, 2012
|
|
3UOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uoz by Molmil](/molmil-images/mine/3uoz) | Crystal Structure of OTEMO complex with FAD and NADP (form 2) | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OTEMO | 著者 | Shi, R, Matte, A, Cygler, M, Lau, P. | 登録日 | 2011-11-17 | 公開日 | 2012-02-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.407 Å) | 主引用文献 | Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-{Delta}(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453. Appl.Environ.Microbiol., 78, 2012
|
|
5N2F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n2f by Molmil](/molmil-images/mine/5n2f) | Structure of PD-L1/small-molecule inhibitor complex | 分子名称: | 4-[[4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-phenyl]methoxy]-2,5-bis(fluoranyl)phenyl]methylamino]-3-oxidanylidene-butanoic acid, Programmed cell death 1 ligand 1 | 著者 | Guzik, K, Zak, K.M, Grudnik, P, Dubin, G, Holak, T.A. | 登録日 | 2017-02-07 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1. J. Med. Chem., 60, 2017
|
|
8JX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jx7 by Molmil](/molmil-images/mine/8jx7) | Cryo-EM structure of human ABC transporter ABCC2 | 分子名称: | ATP-binding cassette sub-family C member 2 | 著者 | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2023-06-30 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
5MZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mzg by Molmil](/molmil-images/mine/5mzg) | Crystal structure of mouse MTH1 in complex with TH588 | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION, ... | 著者 | Narwal, M, Jemth, A.-S, Helleday, T, Stenmark, P. | 登録日 | 2017-01-31 | 公開日 | 2018-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry, 57, 2018
|
|
8JY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jy5 by Molmil](/molmil-images/mine/8jy5) | Cryo-EM structure of human ABC transporter ABCC2 in apo" state | 分子名称: | ATP-binding cassette sub-family C member 2 | 著者 | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2023-07-03 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
1ZIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zig by Molmil](/molmil-images/mine/1zig) | GAGA RNA TETRALOOP, NMR, 10 STRUCTURES | 分子名称: | RNA (5'-R(*GP*GP*GP*CP*GP*AP*GP*AP*GP*CP*CP*U)-3') | 著者 | Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A. | 登録日 | 1996-07-27 | 公開日 | 1997-03-12 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A network of heterogeneous hydrogen bonds in GNRA tetraloops. J.Mol.Biol., 264, 1996
|
|
1ZIH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zih by Molmil](/molmil-images/mine/1zih) | GCAA RNA TETRALOOP, NMR, 10 STRUCTURES | 分子名称: | RNA (5'-R(*GP*GP*GP*CP*GP*CP*AP*AP*GP*CP*CP*U)-3') | 著者 | Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A. | 登録日 | 1996-07-27 | 公開日 | 1997-03-12 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A network of heterogeneous hydrogen bonds in GNRA tetraloops. J.Mol.Biol., 264, 1996
|
|
4EA6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ea6 by Molmil](/molmil-images/mine/4ea6) | Crystal structure of Fungal lipase from Thermomyces(Humicola) lanuginosa at 2.30 Angstrom resolution. | 分子名称: | Lipase | 著者 | Kumar, M, Mukherjee, J, Gupta, M.N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2012-03-22 | 公開日 | 2012-04-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Fungal lipase from Thermomyces(Humicola) lanuginosa at 2.30 Angstrom resolution. To be Published
|
|
8JY4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jy4 by Molmil](/molmil-images/mine/8jy4) | Cryo-EM structure of human ABC transporter ABCC2 in apo' state | 分子名称: | ATP-binding cassette sub-family C member 2 | 著者 | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2023-07-02 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
8JXU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jxu by Molmil](/molmil-images/mine/8jxu) | Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ... | 著者 | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2023-07-01 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
5N5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n5h by Molmil](/molmil-images/mine/5n5h) | Crystal structure of metallo-beta-lactamase VIM-1 in complex with ML302F inhibitor | 分子名称: | (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Salimraj, R, Hinchliffe, P, Spencer, J. | 登録日 | 2017-02-14 | 公開日 | 2018-03-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structures of VIM-1 complexes explain active site heterogeneity in VIM-class metallo-beta-lactamases. FEBS J., 286, 2019
|
|
8JXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jxq by Molmil](/molmil-images/mine/8jxq) | Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2 | 分子名称: | 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL | 著者 | Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2023-07-01 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
|
|
2WYW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wyw by Molmil](/molmil-images/mine/2wyw) | High resolution structure of Thermus thermophilus enoyl-acyl carrier protein reductase NAD and triclosan-form | 分子名称: | ENOYL-[ACYL CARRIER PROTEIN] REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | 著者 | Otero, J.M, Noel, A.J, Guardado-Calvo, P, Llamas-Saiz, A.L, van Raaij, M.J. | 登録日 | 2009-11-20 | 公開日 | 2010-11-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 68, 2012
|
|
4AOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4aoz by Molmil](/molmil-images/mine/4aoz) | B. subtilis dUTPase YncF in complex with dU, PPi and Mg (P212121) | 分子名称: | 2'-DEOXYURIDINE, ACETATE ION, CHLORIDE ION, ... | 著者 | Timm, J, Garcia-Nafria, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. | 登録日 | 2012-03-30 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism Acta Crystallogr.,Sect.D, 69, 2013
|
|
5N5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n5i by Molmil](/molmil-images/mine/5n5i) | Crystal Structure of VIM-1 metallo-beta-lactamase in complex with hydrolysed meropenem | 分子名称: | (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Salimraj, R, Hinchliffe, P, Spencer, J. | 登録日 | 2017-02-14 | 公開日 | 2018-03-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of VIM-1 complexes explain active site heterogeneity in VIM-class metallo-beta-lactamases. FEBS J., 286, 2019
|
|
5N6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n6u by Molmil](/molmil-images/mine/5n6u) | |
2AXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2axb by Molmil](/molmil-images/mine/2axb) | Crystal Structure Analysis Of A 2-O-[2-(methoxy)ethyl]-2-thiothymidine Modified Oligodeoxynucleotide Duplex | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(S2M)P*AP*CP*GP*C)-3') | 著者 | Diop-Frimpong, B, Prakash, T.P, Rajeev, K.G, Manoharan, M, Egli, M. | 登録日 | 2005-09-04 | 公開日 | 2005-11-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines. Nucleic Acids Res., 33, 2005
|
|
2ARR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2arr by Molmil](/molmil-images/mine/2arr) | Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagmggvmtgr-oh | 分子名称: | 14-mer from Plasminogen activator inhibitor-2, Plasminogen activator inhibitor-2 | 著者 | Di Giusto, D.A, Sutherland, A.P, Jankova, L, Harrop, S.J, Curmi, P.M, King, G.C. | 登録日 | 2005-08-21 | 公開日 | 2006-07-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities J.Mol.Biol., 353, 2005
|
|
1ZTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ztg by Molmil](/molmil-images/mine/1ztg) | human alpha polyC binding protein KH1 | 分子名称: | 5'-D(P*CP*CP*CP*TP*CP*CP*CP*T)-3', POLY(RC)-BINDING PROTEIN 1 | 著者 | Sidiqi, M, Wilce, J.A, Barker, A, Schmidgerger, J, Leedman, P.J, Wilce, M.C.J. | 登録日 | 2005-05-27 | 公開日 | 2006-05-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides Nucleic Acids Res., 40, 2012
|
|
5YUM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yum by Molmil](/molmil-images/mine/5yum) | Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs | 分子名称: | Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE | 著者 | Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. | 登録日 | 2017-11-22 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.432 Å) | 主引用文献 | Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
|
|
4ALK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4alk by Molmil](/molmil-images/mine/4alk) | Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol | 分子名称: | 5-ETHYL-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | 登録日 | 2012-03-04 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality Structure, 20, 2012
|
|
2JI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ji3 by Molmil](/molmil-images/mine/2ji3) | X-ray structure of the iron-peroxide intermediate of superoxide reductase (E114A mutant) from Desulfoarculus baarsii | 分子名称: | CALCIUM ION, Desulfoferrodoxin, FE (III) ION, ... | 著者 | Katona, G, Carpentier, P, Niviere, V, Amara, P, Adam, V, Ohana, J, Tsanov, N, Bourgeois, D. | 登録日 | 2007-02-24 | 公開日 | 2007-05-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Raman-assisted crystallography reveals end-on peroxide intermediates in a nonheme iron enzyme. Science, 316, 2007
|
|
4C81
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c81 by Molmil](/molmil-images/mine/4c81) | IspF (Plasmodium falciparum) CDP complex | 分子名称: | 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, ... | 著者 | O'Rourke, P.E.F, Kalinowska-Tluscik, J, Fyfe, P.K, Dawson, A, Hunter, W.N. | 登録日 | 2013-09-27 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Crystal Structures of Ispf from Plasmodium Falciparum and Burkholderia Cenocepacia: Comparisons Inform Antimicrobial Drug Target Assessment. Bmc Struct.Biol., 14, 2014
|
|
2WKN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wkn by Molmil](/molmil-images/mine/2wkn) | gamma lactamase from Delftia acidovorans | 分子名称: | FORMAMIDASE, ZINC ION | 著者 | Isupov, M.N, Line, K, Gonsalvez, I.S, Gange-Harris, P, Lanzotti, M, Saneei, V, Littlechild, J.A. | 登録日 | 2009-06-16 | 公開日 | 2010-09-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The Structure of Gamma Lactamase from Delftia Acidovorans To be Published
|
|