5KUF
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![BU of 5kuf by Molmil](/molmil-images/mine/5kuf) | GluK2EM with 2S,4R-4-methylglutamate | 分子名称: | 2S,4R-4-METHYLGLUTAMATE, Glutamate receptor ionotropic, kainate 2 | 著者 | Meyerson, J.R, Chittori, S, Merk, A, Rao, P, Han, T.H, Serpe, M, Mayer, M.L, Subramaniam, S. | 登録日 | 2016-07-13 | 公開日 | 2016-09-07 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of kainate subtype glutamate receptor desensitization. Nature, 537, 2016
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1WTQ
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![BU of 1wtq by Molmil](/molmil-images/mine/1wtq) | Hyperthermophile chromosomal protein SAC7D single mutant M29F in complex with DNA GTAATTAC | 分子名称: | 5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-binding proteins 7a/7b/7d | 著者 | Chen, C.-Y, Ko, T.-P, Lin, T.-W, Chou, C.-C, Chen, C.-J, Wang, A.H.-J. | 登録日 | 2004-11-29 | 公開日 | 2005-02-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d NUCLEIC ACIDS RES., 33, 2005
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1X3F
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![BU of 1x3f by Molmil](/molmil-images/mine/1x3f) | Crystal structure of the single-stranded DNA-binding protein from Mycobacterium SMEGMATIS | 分子名称: | CADMIUM ION, Single-strand binding protein | 著者 | Saikrishnan, K, Manjunath, G.P, Singh, P, Jeyakanthan, J, Dauter, Z, Sekar, K, Muniyappa, K, Vijayan, M. | 登録日 | 2005-05-05 | 公開日 | 2005-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association. Acta Crystallogr.,Sect.D, 61, 2005
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5KWK
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![BU of 5kwk by Molmil](/molmil-images/mine/5kwk) | The structure of Arabidopsis thaliana FUT1 in complex with GDP | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Alahuhta, P.M, Lunin, V.V. | 登録日 | 2016-07-18 | 公開日 | 2016-09-28 | 最終更新日 | 2018-05-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural, mutagenic and in silico studies of xyloglucan fucosylation in Arabidopsis thaliana suggest a water-mediated mechanism. Plant J., 91, 2017
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5BV7
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![BU of 5bv7 by Molmil](/molmil-images/mine/5bv7) | Crystal structure of human LCAT (L4F, N5D) in complex with Fab of an agonistic antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 27C3 heavy chain, 27C3 light chain, ... | 著者 | Piper, D.E, Romanow, W.G, Thibault, S.T, Walker, N.P.C. | 登録日 | 2015-06-04 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism. J.Biol.Chem., 291, 2016
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5BRE
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![BU of 5bre by Molmil](/molmil-images/mine/5bre) | Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN | 分子名称: | 2-{[(benzyloxy)carbonyl]amino}-2-deoxy-beta-D-glucopyranose, Glucokinase 1, putative | 著者 | D'Antonio, E.L, Perry, K, Deinema, M.S, Kearns, S.P, Frey, T.A. | 登録日 | 2015-05-30 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase. Mol.Biochem.Parasitol., 204, 2016
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3RUT
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![BU of 3rut by Molmil](/molmil-images/mine/3rut) | FXR with SRC1 and GSK359 | 分子名称: | 6-(4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)-1-benzothiophene-3-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1, ... | 著者 | Williams, S.P, Madauss, K.P. | 登録日 | 2011-05-05 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Conformationally constrained farnesoid X receptor (FXR) agonists: Alternative replacements of the stilbene. Bioorg.Med.Chem.Lett., 21, 2011
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5L0Z
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![BU of 5l0z by Molmil](/molmil-images/mine/5l0z) | Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti | 分子名称: | COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ... | 著者 | Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A. | 登録日 | 2016-07-28 | 公開日 | 2017-08-02 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti To Be Published
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1S2P
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![BU of 1s2p by Molmil](/molmil-images/mine/1s2p) | The structure and refinement of apocrustacyanin C2 to 1.3A resolution and the search for differences between this protein and the homologous apoproteins A1 and C1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Crustacyanin C2 subunit, SULFATE ION | 著者 | Habash, J, Helliwell, J.R, Raftery, J, Cianci, M, Rizkallah, P.J, Chayen, N.E, NNeji, G.A, Zakalsky, P.F. | 登録日 | 2004-01-09 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The structure and refinement of apocrustacyanin C2 to 1.3 A resolution and the search for differences between this protein and the homologous apoproteins A1 and C1. Acta Crystallogr.,Sect.D, 60, 2004
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2MNB
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![BU of 2mnb by Molmil](/molmil-images/mine/2mnb) | Thiazotropsin B DNA recognition sequence d(CGACGCGTCG)2 | 分子名称: | 5'-D(*CP*GP*AP*CP*GP*CP*GP*TP*CP*G)-3' | 著者 | Alniss, H.Y, Salvia, M.-V, Sadikov, M, Golovchenko, I, Anthony, N.G, Khalaf, A.I, Mackay, S.P, Suckling, C.J, Parkinson, J.A. | 登録日 | 2014-04-02 | 公開日 | 2014-09-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition of the DNA minor groove by thiazotropsin analogues. Chembiochem, 15, 2014
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2MNE
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![BU of 2mne by Molmil](/molmil-images/mine/2mne) | Recognition complex of DNA d(CGACTAGTCG)2 with thiazotropsin analogue AIK-18/51 | 分子名称: | 5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3', AIK-18/51 | 著者 | Alniss, H.Y, Salvia, M.-V, Sadikov, M, Golovchenko, I, Anthony, N.G, Khalaf, A.I, Mackay, S.P, Suckling, C.J, Parkinson, J.A. | 登録日 | 2014-04-03 | 公開日 | 2014-07-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition of the DNA minor groove by thiazotropsin analogues. Chembiochem, 15, 2014
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5KVA
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![BU of 5kva by Molmil](/molmil-images/mine/5kva) | Crystal Structure of sorghum caffeoyl-CoA O-methyltransferase (CCoAOMT) | 分子名称: | CALCIUM ION, S-ADENOSYLMETHIONINE, caffeoyl-CoA O-methyltransferase | 著者 | Walker, A.M, Sattler, S.A, Regner, M, Jones, J.P, Ralph, J, Vermerris, W, Sattler, S.E, Kang, C. | 登録日 | 2016-07-14 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.827 Å) | 主引用文献 | The Structure and Catalytic Mechanism of Sorghum bicolor Caffeoyl-CoA O-Methyltransferase. Plant Physiol., 172, 2016
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2IK8
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![BU of 2ik8 by Molmil](/molmil-images/mine/2ik8) | Crystal structure of the heterodimeric complex of human RGS16 and activated Gi alpha 1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ... | 著者 | Soundararajan, M, Turnbull, A.P, Papagrigoriou, E, Debreczeni, J, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2006-10-02 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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7SWO
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![BU of 7swo by Molmil](/molmil-images/mine/7swo) | C98C7 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) | 分子名称: | C98C7 Fab heavy chain, C98C7 Fab light chain, Spike protein S1 | 著者 | Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. | 登録日 | 2021-11-20 | 公開日 | 2022-04-27 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol, 7, 2022
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3S3M
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![BU of 3s3m by Molmil](/molmil-images/mine/3s3m) | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and Dolutegravir (S/GSK1349572) | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3', 5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', ... | 著者 | Hare, S, Cherepanov, P. | 登録日 | 2011-05-18 | 公開日 | 2011-07-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572). Mol.Pharmacol., 80, 2011
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7SWP
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![BU of 7swp by Molmil](/molmil-images/mine/7swp) | G32Q4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) | 分子名称: | G32Q4 Fab heavy chain, G32Q4 Fab light chain, Spike protein S1 | 著者 | Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. | 登録日 | 2021-11-20 | 公開日 | 2022-04-27 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol, 7, 2022
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6Y62
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![BU of 6y62 by Molmil](/molmil-images/mine/6y62) | Crystal structure of the envelope glycoprotein complex of Maporal virus in a prefusion conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Serris, A, Rey, F.A, Guardado-Calvo, P. | 登録日 | 2020-02-26 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
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4DDR
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![BU of 4ddr by Molmil](/molmil-images/mine/4ddr) | Human dihydrofolate reductase complexed with NADPH and P218 | 分子名称: | 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Yuthavong, Y, Tarnchompoo, B, Vilaivan, T, Chitnumsub, P, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Thongphanchang, C, Taweechai, S, Vanichtanankul, J, Rattanajak, R, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | 登録日 | 2012-01-19 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
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7SWN
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![BU of 7swn by Molmil](/molmil-images/mine/7swn) | G32A4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) | 分子名称: | G32A4 Fab heavy chain, G32A4 Fab light chain, Spike protein S1 | 著者 | Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. | 登録日 | 2021-11-20 | 公開日 | 2022-04-27 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1. Sci Immunol, 7, 2022
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7EO5
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![BU of 7eo5 by Molmil](/molmil-images/mine/7eo5) | Crystal structure of pyrano 1,3, oxazine derivative in complex with the second bromodomain of BRD2 | 分子名称: | 7-chloranyl-2-[(3-chlorophenyl)amino]pyrano[3,4-e][1,3]oxazine-4,5-dione, Bromodomain-containing protein 2, TRIETHYLENE GLYCOL | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S. | 登録日 | 2021-04-21 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural investigation of a pyrano-1,3-oxazine derivative and the phenanthridinone core moiety against BRD2 bromodomains. Acta Crystallogr.,Sect.F, 78, 2022
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4WWF
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![BU of 4wwf by Molmil](/molmil-images/mine/4wwf) | High-resolution structure of two Ni-bound forms of the M123C mutant of C. metallidurans CnrXs | 分子名称: | NICKEL (II) ION, Nickel and cobalt resistance protein CnrR, SODIUM ION | 著者 | Volbeda, A, Coves, J, Maillard, A.P, Kinnemann, S, Grosse, C, Schleuder, G, Petit-Hurtlein, I, de Rosny, E, Nies, D.H. | 登録日 | 2014-11-10 | 公開日 | 2015-02-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Response of CnrX from Cupriavidus metallidurans CH34 to nickel binding. Metallomics, 7, 2015
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6Y0Z
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![BU of 6y0z by Molmil](/molmil-images/mine/6y0z) | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126K | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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1BEI
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![BU of 1bei by Molmil](/molmil-images/mine/1bei) | Shk-dnp22: A Potent Kv1.3-specific immunosuppressive polypeptide, NMR, 20 structures | 分子名称: | POTASSIUM CHANNEL TOXIN SHK | 著者 | Kalman, K, Pennington, M.W, Lanigan, M.D, Nguyen, A, Rauer, H, Mahnir, V, Gutman, G.A, Paschetto, K, Kem, W.R, Grissmer, S, Christian, E.P, Cahalan, M.D, Norton, R.S, Chandy, K.G. | 登録日 | 1998-05-14 | 公開日 | 1998-12-02 | 最終更新日 | 2022-12-21 | 実験手法 | SOLUTION NMR | 主引用文献 | ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide. J.Biol.Chem., 273, 1998
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1MVL
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![BU of 1mvl by Molmil](/molmil-images/mine/1mvl) | PPC decarboxylase mutant C175S | 分子名称: | FLAVIN MONONUCLEOTIDE, PPC decarboxylase AtHAL3a | 著者 | Steinbacher, S, Hernandez-Acosta, P, Bieseler, B, Blaesse, M, Huber, R, Culianez-Macia, F.A, Kupke, T. | 登録日 | 2002-09-26 | 公開日 | 2003-03-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Plant PPC Decarboxylase AtHAL3a Complexed with an Ene-thiol Reaction Intermediate J.Mol.Biol., 327, 2003
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8IL7
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![BU of 8il7 by Molmil](/molmil-images/mine/8il7) | |