7OG1
| AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | 登録日 | 2021-05-05 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OIQ
| Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) | 分子名称: | AP-2 complex subunit mu, F-BAR domain only protein 2 | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | 登録日 | 2021-05-12 | 公開日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OFP
| Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor | 分子名称: | AP-2 complex subunit mu, CITRIC ACID, GLYCEROL | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | 登録日 | 2021-05-05 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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7OHO
| Crystal structure of AP2 FCHO2 chimera | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | 登録日 | 2021-05-11 | 公開日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
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6YAE
| AP2 core in physiological buffer | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | 著者 | Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G. | 登録日 | 2020-03-12 | 公開日 | 2020-07-29 | 最終更新日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Sci Adv, 6, 2020
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5FJW
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5FRG
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5FJZ
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5FK0
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5FJX
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5FG6
| Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe | 分子名称: | 1,2-ETHANEDIOL, 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide, Bromodomain-containing protein 1, ... | 著者 | Tallant, C, Owen, D.R, Gerstenberger, B.S, Savitsky, P, Chaikuad, A, Fedorov, O, Nunez-Alonso, G, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Knapp, S. | 登録日 | 2015-12-20 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe To Be Published
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5FG5
| Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe | 分子名称: | NITRATE ION, Peregrin, ~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide | 著者 | Tallant, C, Owen, D.R, Gerstenberger, B.S, Savitsky, P, Chaikuad, A, Fedorov, O, Nunez-Alonso, G, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Brennan, P.E, Knapp, S. | 登録日 | 2015-12-20 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe To Be Published
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6H7W
| Model of retromer-Vps5 complex assembled on membrane. | 分子名称: | Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ... | 著者 | Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M. | 登録日 | 2018-07-31 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (11.4 Å) | 主引用文献 | Structure of the membrane-assembled retromer coat determined by cryo-electron tomography. Nature, 561, 2018
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3ZYL
| Structure of a truncated CALM (PICALM) ANTH domain | 分子名称: | PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN | 著者 | Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. | 登録日 | 2011-08-23 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell, 147, 2011
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3ZYM
| Structure of CALM (PICALM) in complex with VAMP8 | 分子名称: | GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ... | 著者 | Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. | 登録日 | 2011-08-23 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell, 147, 2011
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3ZYK
| Structure of CALM (PICALM) ANTH domain | 分子名称: | PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN | 著者 | Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. | 登録日 | 2011-08-23 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell, 147, 2011
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1UQV
| SAM domain from Ste50p | 分子名称: | STE50 PROTEIN | 著者 | Grimshaw, S.J, Mott, H.R, Stott, K.M, Nielsen, P.R, Evetts, K.A, Hopkins, L.J, Nietlispach, D, Owen, D. | 登録日 | 2003-10-20 | 公開日 | 2003-10-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Sterile {Alpha} Motif (Sam) Domain of the Saccharomyces Cerevisiae Mitogen-Activated Protein Kinase Pathway-Modulating Protein Ste50 and Analysis of its Interaction with the Ste11 Sam J.Biol.Chem., 279, 2004
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6R28
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1Z2X
| Crystal structure of mouse Vps29 | 分子名称: | Vacuolar protein sorting 29 | 著者 | Collins, B.M, Skinner, C.F, Watson, P.J, Seaman, M.N.J, Owen, D.J. | 登録日 | 2005-03-10 | 公開日 | 2005-06-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly NAT.STRUCT.MOL.BIOL., 12, 2005
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1Z2W
| Crystal structure of mouse Vps29 complexed with Mn2+ | 分子名称: | GLYCEROL, MANGANESE (II) ION, Vacuolar protein sorting 29 | 著者 | Collins, B.M, Skinner, C.F, Watson, P.J, Seaman, M.N.J, Owen, D.J. | 登録日 | 2005-03-10 | 公開日 | 2005-06-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly NAT.STRUCT.MOL.BIOL., 12, 2005
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5FG4
| Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe | 分子名称: | 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide, Peregrin | 著者 | Tallant, C, Owen, D.R, Gerstenberger, B.S, Savitsky, P, Chaikuad, A, Fedorov, O, Nunez-Alonso, G, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Knapp, S. | 登録日 | 2015-12-20 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe To Be Published
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7BLR
| Vps35/Vps29 arch of fungal membrane-assembled retromer:Vps5 (SNX-BAR) complex. | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | 登録日 | 2021-01-18 | 公開日 | 2021-02-10 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Sci Adv, 7, 2021
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7BLP
| Vps35/Vps29 arch of fungal membrane-assembled retromer:Grd19 complex | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | 登録日 | 2021-01-18 | 公開日 | 2021-02-10 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Sci Adv, 7, 2021
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4AFI
| Complex between Vamp7 longin domain and fragment of delta-adaptin from AP3 | 分子名称: | AP-3 COMPLEX SUBUNIT DELTA-1, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7, PRASEODYMIUM ION | 著者 | Kent, H.M, Evans, P.R, Luzio, J.P, Peden, A.A, Owen, D.J. | 登録日 | 2012-01-19 | 公開日 | 2012-05-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis of the Intracellular Sorting of the Snare Vamp7 by the Ap3 Adaptor Complex Dev.Cell, 22, 2012
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1ZSG
| beta PIX-SH3 complexed with an atypical peptide from alpha-PAK | 分子名称: | Rho guanine nucleotide exchange factor 7, Serine/threonine-protein kinase PAK 1 | 著者 | Mott, H.R, Nietlispach, D, Evetts, K.A, Owen, D. | 登録日 | 2005-05-24 | 公開日 | 2005-08-30 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Analysis of the SH3 Domain of beta-PIX and Its Interaction with alpha-p21 Activated Kinase (PAK) Biochemistry, 44, 2005
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