8BFG
 
 | | Solution structure of human apo/Calmodulin G113R (G114R) | | 分子名称: | Calmodulin-1 | | 著者 | Wimmer, R, Holler, C.V, Petersson, N.M, Brohus, M.B, Niemelae, M, Overgaard, M.T, Iwai, H. | | 登録日 | 2022-10-25 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
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8BD2
 | | Calcium-bound Calmodulin variant G113R | | 分子名称: | CALCIUM ION, Calmodulin-3 | | 著者 | Wimmer, R, Holler, C.V, Petersson, N.M, Iwai, H, Niemelae, M.A, Brohus, M, Overgaard, M.T. | | 登録日 | 2022-10-18 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
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6GDK
 | | Calcium bound form of human calmodulin mutant F141L | | 分子名称: | CALCIUM ION, Calmodulin-1 | | 著者 | Grachov, O, Holt, C, Overgaard, M.T, Wimmer, R. | | 登録日 | 2018-04-23 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6GDL
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6Y94
 | | Ca2+-bound Calmodulin mutant N53I | | 分子名称: | CALCIUM ION, Calmodulin | | 著者 | Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R. | | 登録日 | 2020-03-06 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y4P
 | | Calmodulin N53I variant bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | | 分子名称: | CALCIUM ION, Calmodulin-1, Ryanodine receptor 2 | | 著者 | Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R. | | 登録日 | 2020-02-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.13325572 Å) | | 主引用文献 | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y95
 | | Ca2+-free Calmodulin mutant N53I | | 分子名称: | Calmodulin | | 著者 | Holt, C, Hamborg, L.N, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R. | | 登録日 | 2020-03-06 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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6Y4O
 | | Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | | 分子名称: | CALCIUM ION, Calmodulin-2, Ryanodine receptor 2 | | 著者 | Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R. | | 登録日 | 2020-02-21 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.83549082 Å) | | 主引用文献 | The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
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3DBK
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