4EF4
 
 | | Crystal structure of STING CTD complex with c-di-GMP | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | | Authors: | Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J. | | Deposit date: | 2012-03-29 | | Release date: | 2012-05-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.147 Å) | | Cite: | Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
|
|
4DKS
 | | A spindle-shaped virus protein (chymotrypsin treated) | | Descriptor: | Probable integrase | | Authors: | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | | Deposit date: | 2012-02-04 | | Release date: | 2012-05-30 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase.
Acta Crystallogr.,Sect.D, 68, 2012
|
|
4WYH
 | |
3VCF
 | | SSV1 integrase C-terminal catalytic domain (174-335aa) | | Descriptor: | Probable integrase | | Authors: | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | | Deposit date: | 2012-01-04 | | Release date: | 2012-05-30 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase.
Acta Crystallogr.,Sect.D, 68, 2012
|
|
8IPJ
 | | Crystal structure of the Legionella effector protein MavL with ADPR-Ub | | Descriptor: | MavL, Ubiquitin, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | Authors: | Ouyang, S, Guan, H. | | Deposit date: | 2023-03-14 | | Release date: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.003 Å) | | Cite: | Crystal structure of the Legionella effector protein MavL with ADPR-Ub
To Be Published
|
|
8IPW
 | | The sturecture of Legionella effector protein MavL with ADPR | | Descriptor: | MavL, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | Authors: | Ouyang, S, Hongxin, G. | | Deposit date: | 2023-03-15 | | Release date: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The sturecture of Legionella effector protein MavL with ADPR
To Be Published
|
|
6M6U
 | | Crystal structure the toxin-antitoxin MntA-HpeT mutant-D39ED41E | | Descriptor: | Toxin-antitoxin system antitoxin MntA family, Toxin-antitoxin system toxin HepN family | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-03-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.349 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
|
|
6M6W
 | | Crystal structure the toxin-antitoxin MntA-HpeT mutant-Y104A | | Descriptor: | Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-03-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.611 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
|
|
6M6V
 | | Crystal structure the toxin-antitoxin MntA-HepT | | Descriptor: | RNA (5'-R(P*AP*AP*A)-3'), Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-03-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
|
|
3UX9
 | | Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus | | Descriptor: | Interferon alpha-1/13, ScFv antibody | | Authors: | Ouyang, S, Zhao, L.X, Liang, W, Shaw, N, Liu, Z.-J, Liang, M.-F. | | Deposit date: | 2011-12-04 | | Release date: | 2012-02-29 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
J.Mol.Med., 2012
|
|
8I3Q
 | |
7CNB
 | |
7XVG
 | | Cryo-EM structure of binary complex of plant NLR Sr35 and effector AvrSr35 | | Descriptor: | AvrSr35, Sr35 | | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | | Deposit date: | 2022-05-23 | | Release date: | 2022-09-28 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.
Sci Adv, 8, 2022
|
|
7BXO
 | | Crystal structure of the toxin-antitoxin with AMP-PNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Toxin-antitoxin system antidote Mnt family, ... | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-04-20 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
|
|
7XX2
 | | Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, CNL9 | | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | | Deposit date: | 2022-05-28 | | Release date: | 2022-11-02 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.
Sci Adv, 8, 2022
|
|
7BU0
 | |
4EF5
 | | Crystal structure of STING CTD | | Descriptor: | Transmembrane protein 173 | | Authors: | Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J. | | Deposit date: | 2012-03-29 | | Release date: | 2012-05-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
|
|
5FAD
 | | SAH complex with aKMT from the hyperthermophilic archaeon Sulfolobus islandicus | | Descriptor: | MAGNESIUM ION, Ribosomal protein L11 methyltransferase, putative, ... | | Authors: | Ouyang, S. | | Deposit date: | 2015-12-11 | | Release date: | 2016-06-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism
Mol.Cell Proteomics, 15, 2016
|
|
5FA8
 | | SAM complex with aKMT from the hyperthermophilic archaeon Sulfolobus islandicu | | Descriptor: | MAGNESIUM ION, Ribosomal protein L11 methyltransferase, putative, ... | | Authors: | Ouyang, S. | | Deposit date: | 2015-12-11 | | Release date: | 2016-06-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism
Mol.Cell Proteomics, 15, 2016
|
|
7WCF
 | | Crystal structure of the kinase with AMP-PNP | | Descriptor: | HipA_C domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | Authors: | Ouyang, S.Y, Zhen, X. | | Deposit date: | 2021-12-20 | | Release date: | 2022-06-29 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.3636 Å) | | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila.
Nat Commun, 13, 2022
|
|
6M39
 | | Cryo-EM structure of SADS-CoV spike | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Ouyang, S, Hongxin, G. | | Deposit date: | 2020-03-03 | | Release date: | 2020-08-26 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Cryo-electron Microscopy Structure of the Swine Acute Diarrhea Syndrome Coronavirus Spike Glycoprotein Provides Insights into Evolution of Unique Coronavirus Spike Proteins.
J.Virol., 94, 2020
|
|
7W3S
 | | The complex structure of Larg1-ADPr from Legionella pneumophila | | Descriptor: | Type IV secretion protein Dot, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | Authors: | Ouyang, S, Guan, H, Li, P. | | Deposit date: | 2021-11-26 | | Release date: | 2022-04-06 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.324 Å) | | Cite: | Legionella pneumophila temporally regulates the activity of ADP/ATP translocases by reversible ADP-ribosylation.
mLife, 2022
|
|
7XDS
 | |
7XE0
 | | Cryo-EM structure of plant NLR Sr35 resistosome | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, Sr35 | | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | | Deposit date: | 2022-03-29 | | Release date: | 2022-09-28 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.
Sci Adv, 8, 2022
|
|
7DMS
 | |
