6NN3
 
 | | Structure of parvovirus B19 decorated with Fab molecules from a human antibody | | 分子名称: | Fab monoclonal antibody 860-55D, heavy chain, light chain, ... | | 著者 | Rossmann, M.G, Sun, Y, Klose, T, Liu, Y. | | 登録日 | 2019-01-14 | | 公開日 | 2019-02-13 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody.
J. Virol., 93, 2019
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6MWC
 | | CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody | | 分子名称: | E1, E2, EEEV-5 antibody heavy chain, ... | | 著者 | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | | 登録日 | 2018-10-29 | | 公開日 | 2018-12-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
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6WDT
 | | Enterovirus D68 in complex with human monoclonal antibody EV68-228 | | 分子名称: | EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ... | | 著者 | Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-04-01 | | 公開日 | 2020-07-15 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
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6PSF
 | | Rhinovirus C15 complexed with domains I and II of receptor CDHR3 | | 分子名称: | Cadherin-related family member 3, Capsid protein VP1, Capsid protein VP2, ... | | 著者 | Sun, Y, Watters, K, Klose, T, Palmenberg, A.C. | | 登録日 | 2019-07-12 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7T9P
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7TAH
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7TAJ
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7TAF
 | | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092 | | 分子名称: | N,N-dimethyl-5-(3-{2-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy}propyl)-1,2-oxazole-3-carboxamide, viral protein 1, viral protein 2, ... | | 著者 | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-12-20 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
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7TAG
 | | Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril | | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, viral protein 1, viral protein 2, ... | | 著者 | Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-12-20 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
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7XJB
 | | Rat-COMT, opicapone,SAM and Mg bond | | 分子名称: | CHLORIDE ION, Catechol O-methyltransferase, MAGNESIUM ION, ... | | 著者 | Takebe, K, Iijima, H, Suzuki, M, Kuwada-Kusunose, T. | | 登録日 | 2022-04-15 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Computational Analyses of the Unique Interactions of Opicapone in the Binding Pocket of Catechol O -Methyltransferase: A Crystallographic Study and Fragment Molecular Orbital Analyses.
J.Chem.Inf.Model., 63, 2023
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7XGI
 | | COMT SAH Mg opicapone complex | | 分子名称: | Catechol O-methyltransferase, MAGNESIUM ION, Opicapone, ... | | 著者 | Takebe, K, Kuwada-Kusunose, T, Suzuki, M, Iijima, H. | | 登録日 | 2022-04-04 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Computational Analyses of the Unique Interactions of Opicapone in the Binding Pocket of Catechol O -Methyltransferase: A Crystallographic Study and Fragment Molecular Orbital Analyses.
J.Chem.Inf.Model., 63, 2023
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7KH1
 | | Baseplate Complex for Myoviridae Phage XM1 | | 分子名称: | baseplate organization protein, gp11, baseplate stabilizing protein, ... | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-10-19 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KLN
 | | Myoviridae Phage XM1 Neck Region (12-fold) | | 分子名称: | Head completion protein, gp1, Portal protein | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-10-30 | | 公開日 | 2021-11-03 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KJK
 | | The Neck region of Phage XM1 (6-fold symmetry) | | 分子名称: | Collar spike protein, Head completion protein, Tail sheath protein, ... | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-10-26 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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7KMX
 | | The capsid of Myoviridae Phage XM1 | | 分子名称: | Major capsid protein, Minor capsid protein | | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | | 登録日 | 2020-11-03 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
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3GJL
 | | crystal structure of a DNA duplex containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one | | 分子名称: | 5'-D(*CP*GP*CP*GP*AP*A)-3', 5'-D(P*TP*TP*(B7C)P*GP*CP*G)-3', SODIUM ION | | 著者 | Takenaka, A, Juan, E.C.M, Shimizu, S, Haraguchi, T, Xiao, M, Kurose, T, Ohkubo, A, Sekine, M, Shibata, T, Millington, C.L, Williams, D.M. | | 登録日 | 2009-03-09 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Insights into the stabilizing contributions of bicyclic cytosine analogues: crystal structures of DNA duplexes containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one
To be Published
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6K3N
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8T0Q
 | | Open state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis | | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... | | 著者 | Tian, S, Voss, P, Pham, K, Klose, T. | | 登録日 | 2023-06-01 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase
To Be Published
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8T0V
 | | Closed state of lysine 5,6-aminomutase from Thermoanaerobacter tengcongensis | | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, D-lysine 5,6-aminomutase alpha subunit, ... | | 著者 | Tian, S, Voss, P, Pham, K, Klose, T. | | 登録日 | 2023-06-01 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Catalysis in Motion: Large-Scale Domain Shift Enables Co-C Bond Homolysis in Lysine 5,6-Aminomutase
To Be Published
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7N69
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7N6A
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7LCG
 | | The mature Usutu SAAR-1776, Model A | | 分子名称: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | 著者 | Khare, B, Klose, T, Fang, Q, Kuhn, R. | | 登録日 | 2021-01-11 | | 公開日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7LCH
 | | The mature Usutu SAAR-1776, Model B | | 分子名称: | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | 著者 | Khare, B, Klose, T, Fang, Q, Kuhn, R. | | 登録日 | 2021-01-11 | | 公開日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | | 主引用文献 | Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7V0N
 | | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-21 | | 分子名称: | IgG 21 Fab heavy chain, IgG 21 Fab light chain, Spike glycoprotein E1, ... | | 著者 | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | | 登録日 | 2022-05-10 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7V0O
 | | Cryo-EM structure of SINV/EEEV in complex with Fab fragment of a moderately/weakly neutralizing human antibody IgG-94 | | 分子名称: | IgG 94 Fab heavy chain, IgG 94 Fab light chain, Spike glycoprotein E1, ... | | 著者 | Bandyopadhyay, A, Klose, T, Kuhn, R.J. | | 登録日 | 2022-05-10 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 120, 2023
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