4A4M
 
 | | Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin mutant in complex with a peptide resembling the C-terminus of the Galpha-protein subunit (GaCT) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-3, ... | | 著者 | Deupi, X, Edwards, P, Singhal, A, Nickle, B, Oprian, D.D, Schertler, G.F.X, Standfuss, J. | | 登録日 | 2011-10-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Stabilized G Protein Binding Site in the Structure of Constitutively Active Metarhodopsin-II.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4M2P
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2X72
 | | CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE. | | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ACETATE ION, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | | 著者 | Standfuss, J, Edwards, P.C, Dantona, A, Fransen, M, Xie, G, Oprian, D.D, Schertler, G.F.X. | | 登録日 | 2010-02-22 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin
Nature, 471, 2011
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2J4Y
 | | Crystal structure of a rhodopsin stabilizing mutant expressed in mammalian cells | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RETINAL, RHODOPSIN | | 著者 | Standfuss, J, Xie, G, Edwards, P.C, Burghammer, M, Oprian, D.D, Schertler, G.F.X. | | 登録日 | 2006-09-07 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal Structure of a Thermally Stable Rhodopsin Mutant.
J.Mol.Biol., 372, 2007
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6ONM
 | | Crystal Structure of (+)-Limonene Synthase Complexed with 8,9-Difluorolinalyl Diphosphate | | 分子名称: | (+)-limonene synthase, (3R)-8-fluoro-7-(fluoromethyl)-3-methylocta-1,6-dien-3-yl trihydrogen diphosphate, MANGANESE (II) ION | | 著者 | Prem Kumar, R, Morehouse, B.R, Yu, Q, Oprian, D.D. | | 登録日 | 2019-04-22 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Direct Evidence of an Enzyme-Generated LPP Intermediate in (+)-Limonene Synthase Using a Fluorinated GPP Substrate Analog.
Acs Chem.Biol., 14, 2019
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9C7K
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9C7L
 | | Crystal structure of pentalenene synthase variant F76A complexed with 2-fluorofarnesyl diphosphate | | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, Pentalenene synthase | | 著者 | Prem Kumar, R, Ellenburg, W.H, Oprian, D.D. | | 登録日 | 2024-06-10 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction.
Biochemistry, 2024
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9C7M
 | | Crystal structure of pentalenene synthase variant F76A complexed with 12,13-difluorofarnesyl diphosphate | | 分子名称: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, Pentalenene synthase | | 著者 | Prem Kumar, R, Ellenburg, W.H, Oprian, D.D. | | 登録日 | 2024-06-10 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction.
Biochemistry, 2024
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9C7J
 | | Crystal structure of caryolan-1-ol synthase complexed with 2-fluorofarnesyl diphosphate | | 分子名称: | (+)-caryolan-1-ol synthase, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, DIPHOSPHATE, ... | | 著者 | Prem Kumar, R, Black, B.Y, Oprian, D.D. | | 登録日 | 2024-06-10 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction.
Biochemistry, 2024
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9C7I
 | | Crystal structure of caryolan-1-ol synthase from S. griseus with PEG molecule in the active site | | 分子名称: | (+)-caryolan-1-ol synthase, CALCIUM ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Prem Kumar, R, Matos, J.O, Oprian, D.D. | | 登録日 | 2024-06-10 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction.
Biochemistry, 2024
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6AO9
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6AOA
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6AOB
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5UV1
 | | Crystal Structure of (+)-Limonene Synthase Complexed with 2-Fluorogeranyl Diphosphate | | 分子名称: | (+)-limonene synthase, (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, MANGANESE (II) ION | | 著者 | Prem Kumar, R, Malik, K, Oprian, D.D. | | 登録日 | 2017-02-17 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues.
Biochemistry, 56, 2017
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5VYD
 | | Crystal structure of phosphodiesterase domain of RhoPDE fusion protein from the Choanoflagellate Salpingoeca rosetta | | 分子名称: | MAGNESIUM ION, Phosphodiesterase, ZINC ION | | 著者 | Prem Kumar, R, Lamarche, L.B, Oprian, D.D. | | 登録日 | 2017-05-25 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetic Tool from the Choanoflagellate Salpingoeca rosetta.
Biochemistry, 56, 2017
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5UV2
 | | Crystal Structure of (+)-Limonene Synthase Complexed with 2-Fluoroneryl Diphosphate | | 分子名称: | (+)-limonene synthase, (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, MANGANESE (II) ION | | 著者 | Prem Kumar, R, Malik, K, Oprian, D.D. | | 登録日 | 2017-02-17 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues.
Biochemistry, 56, 2017
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5UV0
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4YI9
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4YI8
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4M2O
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4M2Q
 | | Crystal structure of non-myristoylated recoverin with Cysteine-39 oxidized to sulfenic acid | | 分子名称: | CALCIUM ION, Recoverin | | 著者 | Prem Kumar, R, Chakrabarti, K, Kern, D, Oprian, D.D. | | 登録日 | 2013-08-05 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to Recoverin.
J.Biol.Chem., 288, 2013
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4MLW
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6WKH
 | | Crystal structure of pentalenene synthase mutant F76W complexed with 12,13-difluorofarnesyl diphosphate | | 分子名称: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Pentalenene synthase | | 著者 | Prem Kumar, R, Matos, J.O, Oprian, D.D. | | 登録日 | 2020-04-16 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Mechanism Underlying Anti-Markovnikov Addition in the Reaction of Pentalenene Synthase.
Biochemistry, 59, 2020
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6WKJ
 | | Crystal structure of pentalenene synthase mutant F76H complexed with 12,13-difluorofarnesyl diphosphate | | 分子名称: | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Pentalenene synthase | | 著者 | Prem Kumar, R, Matos, J.O, Oprian, D.D. | | 登録日 | 2020-04-16 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mechanism Underlying Anti-Markovnikov Addition in the Reaction of Pentalenene Synthase.
Biochemistry, 59, 2020
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6WKG
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