5VYD

Crystal structure of phosphodiesterase domain of RhoPDE fusion protein from the Choanoflagellate Salpingoeca rosetta

Summary for 5VYD

Entry DOI	10.2210/pdb5vyd/pdb
Descriptor	Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	pde, cgmp specific, enzyme, alpha helical, metal binding, hydrolase
Biological source	Salpingoeca rosetta (strain ATCC 50818 / BSB-021)
Total number of polymer chains	2
Total formula weight	73841.14
Authors	Prem Kumar, R.,Lamarche, L.B.,Oprian, D.D. (deposition date: 2017-05-25, release date: 2017-10-18, Last modification date: 2023-10-04)
Primary citation	Lamarche, L.B.,Kumar, R.P.,Trieu, M.M.,Devine, E.L.,Cohen-Abeles, L.E.,Theobald, D.L.,Oprian, D.D. Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetic Tool from the Choanoflagellate Salpingoeca rosetta. Biochemistry, 56:5812-5822, 2017 Cited by PubMed: 28976747 DOI: 10.1021/acs.biochem.7b00519 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation