6JJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jjh by Molmil](/molmil-images/mine/6jjh) | Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4 | 分子名称: | (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3') | 著者 | Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G. | 登録日 | 2019-02-25 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths. Nucleic Acids Res., 48, 2020
|
|
6JJF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jjf by Molmil](/molmil-images/mine/6jjf) | Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex | 分子名称: | COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ... | 著者 | Zhang, Y.S, EI Omari, K, Duman, R, Wagner, A, Parkinson, G.N, Wei, D.G. | 登録日 | 2019-02-25 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths. Nucleic Acids Res., 48, 2020
|
|
6OWZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6owz by Molmil](/molmil-images/mine/6owz) | Spy H96L:Im7 L19pI-Phe complex; multiple anomalous datasets contained herein for element identification | 分子名称: | CHLORIDE ION, IMIDAZOLE, IODIDE ION, ... | 著者 | Rocchio, S, Duman, R, El Omari, K, Mykhaylyk, V, Yan, Z, Wagner, A, Bardwell, J.C.A, Horowitz, S. | 登録日 | 2019-05-12 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Identifying dynamic, partially occupied residues using anomalous scattering. Acta Crystallogr D Struct Biol, 75, 2019
|
|
7QU8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qu8 by Molmil](/molmil-images/mine/7qu8) | ADGRG3/GPR97 Extracellular Region | 分子名称: | Adhesion G protein-coupled receptor G3 | 著者 | Zheng-Gerard, C, Chu, T.Y, El Omari, K, Lin, H.H, Seiradake, E. | 登録日 | 2022-01-17 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | GPR97-mediated PAR2 transactivation via a mPR3-associated macromolecular complex induces inflammatory activation of human neutrophils Nat Commun, 2022
|
|
5MDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mdu by Molmil](/molmil-images/mine/5mdu) | Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe. | 分子名称: | CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ... | 著者 | Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J. | 登録日 | 2016-11-13 | 公開日 | 2017-04-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA. Nat Commun, 8, 2017
|
|
6RVC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rvc by Molmil](/molmil-images/mine/6rvc) | Crystal structure of Patched-1 ectodomain 2 (PTCH1-ECD2) in complex with nanobody 75 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody NB75, Protein patched homolog 1, ... | 著者 | Rudolf, A.F, Kowatsch, C, El Omari, K, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | 登録日 | 2019-05-31 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
|
|
6RVD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rvd by Molmil](/molmil-images/mine/6rvd) | Revised cryo-EM structure of the human 2:1 Ptch1-Shh complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | El Omari, K, Rudolf, A.F, Kowatsch, C, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | 登録日 | 2019-05-31 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
|
|
5D9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d9a by Molmil](/molmil-images/mine/5d9a) | Influenza C Virus RNA-dependent RNA Polymerase - Space group P212121 | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | 著者 | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | 登録日 | 2015-08-18 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus. Nature, 527, 2015
|
|
6J7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j7v by Molmil](/molmil-images/mine/6j7v) | |
4BLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4blo by Molmil](/molmil-images/mine/4blo) | P4 PROTEIN FROM BACTERIOPHAGE PHI6 IN COMPLEX WITH ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PACKAGING ENZYME P4 | 著者 | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | 登録日 | 2013-05-04 | 公開日 | 2013-08-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
|
|
6HY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hy0 by Molmil](/molmil-images/mine/6hy0) | Atomic models of P1, P4 C-terminal fragment and P8 fitted in the bacteriophage phi6 nucleocapsid reconstructed with icosahedral symmetry | 分子名称: | Major Outer Capsid Protein P8, Major inner protein P1, Packaging Enzyme P4 | 著者 | El Omari, K, Ilca, S.L, Stuart, D.I, Huiskonen, J.T. | 登録日 | 2018-10-18 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus. Nature, 570, 2019
|
|
6RTW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rtw by Molmil](/molmil-images/mine/6rtw) | Crystal structure of the Patched-1 (PTCH1) ectodomain in complex with nanobody NB64 and cholesterol-hemisuccinate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Llama-derived nanobody NB64, ... | 著者 | Rudolf, A.F, Kowatsch, C, El Omari, K, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | 登録日 | 2019-05-27 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
|
|
6RTX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rtx by Molmil](/molmil-images/mine/6rtx) | Crystal structure of the Patched-1 (PTCH1) ectodomain 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1 | 著者 | Rudolf, A.F, Kowatsch, C, El Omari, K, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | 登録日 | 2019-05-27 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
|
|
4BWY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bwy by Molmil](/molmil-images/mine/4bwy) | P4 PROTEIN FROM BACTERIOPHAGE PHI8 (R32) | 分子名称: | P4 | 著者 | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | 登録日 | 2013-07-05 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
|
|
6RTY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rty by Molmil](/molmil-images/mine/6rty) | Crystal structure of the Patched ectodomain in complex with nanobody NB64 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Llama-derived nanobody NB64, Protein patched homolog 1 | 著者 | Rudolf, A.F, Kowatsch, C, El Omari, K, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | 登録日 | 2019-05-27 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
|
|
5D98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d98 by Molmil](/molmil-images/mine/5d98) | Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212 | 分子名称: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E. | 登録日 | 2015-08-18 | 公開日 | 2015-10-21 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Crystal structure of the RNA-dependent RNA polymerase from influenza C virus. Nature, 527, 2015
|
|
5DOE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5doe by Molmil](/molmil-images/mine/5doe) | Crystal structure of the Human Cytomegalovirus UL53 (residues 72-292) | 分子名称: | Virion egress protein UL31 homolog, ZINC ION | 著者 | Lye, M.F, El Omari, K, Filman, D.J, Hogle, J.M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex. Embo J., 34, 2015
|
|
5DOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dob by Molmil](/molmil-images/mine/5dob) | Crystal structure of the Human Cytomegalovirus Nuclear Egress Complex (NEC) | 分子名称: | CALCIUM ION, Virion egress protein UL31 homolog, Virion egress protein UL34 homolog, ... | 著者 | Lye, M.F, El Omari, K, Filman, D.J, Hogle, J.M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex. Embo J., 34, 2015
|
|
5DOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5doc by Molmil](/molmil-images/mine/5doc) | Crystal structure of the Human Cytomegalovirus UL53 subunit of the NEC | 分子名称: | GLYCEROL, Virion egress protein UL31 homolog, ZINC ION | 著者 | Lye, M.F, El Omari, K, Filman, D.J, Hogle, J.M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex. Embo J., 34, 2015
|
|
4A04
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a04 by Molmil](/molmil-images/mine/4a04) | Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome | 分子名称: | DNA, T-BOX TRANSCRIPTION FACTOR TBX1 | 著者 | El Omari, K, De Mesmaeker, J, Karia, D, Ginn, H, Bhattacharya, S, Mancini, E.J. | 登録日 | 2011-09-07 | 公開日 | 2011-10-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structure of the DNA-Bound T-Box Domain of Human Tbx1, a Transcription Factor Associated with the Digeorge Syndrome Proteins, 80, 2012
|
|
4BLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4blp by Molmil](/molmil-images/mine/4blp) | P4 PROTEIN FROM BACTERIOPHAGE PHI13 | 分子名称: | CITRATE ANION, GLYCEROL, PACKAGING ENZYME P4 | 著者 | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | 登録日 | 2013-05-04 | 公開日 | 2013-08-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
|
|
4BLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4blt by Molmil](/molmil-images/mine/4blt) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 S292A MUTANT IN COMPLEX WITH AMPcPP | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, NTPASE P4 | 著者 | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | 登録日 | 2013-05-04 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
|
|
4BLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4blr by Molmil](/molmil-images/mine/4blr) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH UTP | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NTPASE P4, URIDINE 5'-TRIPHOSPHATE | 著者 | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | 登録日 | 2013-05-04 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
|
|
8PXH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pxh by Molmil](/molmil-images/mine/8pxh) | Structure of TauA from E. coli, solved at wavelength 2.375 A | 分子名称: | 2-AMINOETHANESULFONIC ACID, IODIDE ION, Taurine ABC transporter substrate-binding protein | 著者 | El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Qu, F, Beis, K, Wagner, A. | 登録日 | 2023-07-23 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Commun Chem, 6, 2023
|
|
8PX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8px7 by Molmil](/molmil-images/mine/8px7) | Structure of Bacterial Multidrug Efflux transporter AcrB, solved at wavelength 3.02 A | 分子名称: | Multidrug efflux pump subunit AcrB | 著者 | El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Qu, F, Beis, K, Wagner, A. | 登録日 | 2023-07-22 | 公開日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Commun Chem, 6, 2023
|
|