1ZYK
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![BU of 1zyk by Molmil](/molmil-images/mine/1zyk) | Anthranilate Phosphoribosyltransferase in complex with PRPP, anthranilate and magnesium | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, ... | Authors: | Marino, M, Deuss, M, Sterner, R, Mayans, O. | Deposit date: | 2005-06-10 | Release date: | 2006-05-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. J.Biol.Chem., 281, 2006
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2FLH
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![BU of 2flh by Molmil](/molmil-images/mine/2flh) | Crystal structure of cytokinin-specific binding protein from mung bean in complex with cytokinin | Descriptor: | (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, SODIUM ION, cytokinin-specific binding protein | Authors: | Pasternak, O, Bujacz, G.D, Sikorski, M.M, Jaskolski, M. | Deposit date: | 2006-01-06 | Release date: | 2006-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal Structure of Vigna radiata Cytokinin-Specific Binding Protein in Complex with Zeatin. Plant Cell, 18, 2006
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1BPH
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![BU of 1bph by Molmil](/molmil-images/mine/1bph) | CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | Descriptor: | 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 9), INSULIN B CHAIN (PH 9), ... | Authors: | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | Deposit date: | 1992-10-30 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
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5TR3
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![BU of 5tr3 by Molmil](/molmil-images/mine/5tr3) | 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-25 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD. To Be Published
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5TRE
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![BU of 5tre by Molmil](/molmil-images/mine/5tre) | Zinc and the Iron Donor Frataxin Regulate Oligomerization of the Scaffold Protein to Form New Fe-S Cluster Assembly Centers | Descriptor: | Frataxin homolog, mitochondrial, Iron sulfur cluster assembly protein 1 | Authors: | Ranatunga, W, Gakh, O, Galeano, B.K, Smith IV, D.Y, Thompson, J.R, Isaya, G. | Deposit date: | 2016-10-26 | Release date: | 2017-06-07 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (15.6 Å) | Cite: | Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers. Metallomics, 9, 2017
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7KZX
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![BU of 7kzx by Molmil](/molmil-images/mine/7kzx) | Cryo-EM structure of YiiP-Fab complex in Apo state | Descriptor: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain | Authors: | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | Deposit date: | 2020-12-10 | Release date: | 2021-01-06 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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5TSE
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![BU of 5tse by Molmil](/molmil-images/mine/5tse) | 2.35 Angstrom Crystal Structure Minor Lipoprotein from Acinetobacter baumannii. | Descriptor: | FORMIC ACID, LPS-assembly lipoprotein LptE | Authors: | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-28 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | 2.35 Angstrom Crystal Structure Minor Lipoprotein from Acinetobacter baumannii. To Be Published
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5U0D
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![BU of 5u0d by Molmil](/molmil-images/mine/5u0d) | Identification of a New Zinc Binding Chemotype by Fragment Screening | Descriptor: | (5R)-5-(2,4-dimethoxyphenyl)-2-sulfanylidene-1,3-oxazolidin-4-one, Carbonic anhydrase 2, GLYCEROL, ... | Authors: | Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. | Deposit date: | 2016-11-23 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
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7KZZ
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![BU of 7kzz by Molmil](/molmil-images/mine/7kzz) | Cryo-EM structure of YiiP-Fab complex in Holo state | Descriptor: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ... | Authors: | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | Deposit date: | 2020-12-10 | Release date: | 2021-01-06 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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3KBC
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![BU of 3kbc by Molmil](/molmil-images/mine/3kbc) | Crystal structure of GltPh K55C-A364C mutant crosslinked with divalent mercury | Descriptor: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, MERCURY (II) ION, ... | Authors: | Reyes, N, Ginter, C, Boudker, O. | Deposit date: | 2009-10-20 | Release date: | 2009-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | Transport mechanism of a bacterial homologue of glutamate transporters. Nature, 462, 2009
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5U8T
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![BU of 5u8t by Molmil](/molmil-images/mine/5u8t) | Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications | Descriptor: | Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ... | Authors: | Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E. | Deposit date: | 2016-12-15 | Release date: | 2017-02-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5TR7
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![BU of 5tr7 by Molmil](/molmil-images/mine/5tr7) | Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961 | Descriptor: | D-alanyl-D-alanine carboxypeptidase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Shatsman, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-25 | Release date: | 2016-11-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a putative D-alanyl-D-alanine carboxypeptidase from Vibrio cholerae O1 biovar eltor str. N16961 To Be Published
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5UBD
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![BU of 5ubd by Molmil](/molmil-images/mine/5ubd) | Crystal structure of the N-terminal domain (domain 1) of RctB, RctB-1-124-L48M | Descriptor: | RctB replication initiator protein | Authors: | Orlova, N, Ivashkiv, O, Waldor, M.K, Jeruzalmi, D. | Deposit date: | 2016-12-20 | Release date: | 2017-01-11 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators. Nucleic Acids Res., 45, 2017
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5TY8
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![BU of 5ty8 by Molmil](/molmil-images/mine/5ty8) | Identification of a New Zinc Binding Chemotype by Fragment Screening | Descriptor: | (5R)-5-phenyl-1,3-oxazolidine-2,4-dione, Carbonic anhydrase 2, ZINC ION | Authors: | Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. | Deposit date: | 2016-11-18 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
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1BVT
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![BU of 1bvt by Molmil](/molmil-images/mine/1bvt) | METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS 569/H/9 | Descriptor: | BICARBONATE ION, PROTEIN (BETA-LACTAMASE), ZINC ION | Authors: | Carfi, A, Duee, E, Dideberg, O. | Deposit date: | 1998-09-18 | Release date: | 1998-09-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1.85 A resolution structure of the zinc (II) beta-lactamase from Bacillus cereus. Acta Crystallogr.,Sect.D, 54, 1998
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3KBO
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![BU of 3kbo by Molmil](/molmil-images/mine/3kbo) | 2.14 Angstrom Crystal Structure of Putative Oxidoreductase (ycdW) from Salmonella typhimurium in Complex with NADP | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Glyoxylate/hydroxypyruvate reductase A, ... | Authors: | Minasov, G, Wawrzak, Z, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-10-20 | Release date: | 2009-10-27 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | 2.14 Angstrom Crystal Structure of Putative Oxidoreductase (ycdW) from Salmonella typhimurium in Complex with NADP. To be Published
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3KZF
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![BU of 3kzf by Molmil](/molmil-images/mine/3kzf) | Structure of Giardia Carbamate Kinase | Descriptor: | Carbamate kinase, GLYCEROL | Authors: | Galkin, A, Herzberg, O. | Deposit date: | 2009-12-08 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray structure and characterization of carbamate kinase from the human parasite Giardia lamblia. Acta Crystallogr.,Sect.F, 66, 2010
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5TP0
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![BU of 5tp0 by Molmil](/molmil-images/mine/5tp0) | Human mesotrypsin in complex with diminazene | Descriptor: | BERENIL, CALCIUM ION, SULFATE ION, ... | Authors: | Kayode, O, Soares, A, Radisky, E.S. | Deposit date: | 2016-10-19 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Small molecule inhibitors of mesotrypsin from a structure-based docking screen. PLoS ONE, 12, 2017
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5TRO
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![BU of 5tro by Molmil](/molmil-images/mine/5tro) | 1.8 Angstrom Resolution Crystal Structure of Dimerization and Transpeptidase domains (residues 39-608) of Penicillin-Binding Protein 1 from Staphylococcus aureus. | Descriptor: | CHLORIDE ION, Penicillin-binding protein 1 | Authors: | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-10-26 | Release date: | 2016-11-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 1.8 Angstrom Resolution Crystal Structure of Dimerization and Transpeptidase domains (residues 39-608) of Penicillin-Binding Protein 1 from Staphylococcus aureus. To Be Published
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3KIH
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![BU of 3kih by Molmil](/molmil-images/mine/3kih) | The crystal structures of two fragments truncated from 5-bladed beta-propeller lectin, tachylectin-2 (Lib2-D2-15) | Descriptor: | 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, 5-bladed beta-propeller lectin | Authors: | Dym, O, Tawfik, D.S, Yadid, I, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2009-11-02 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Metamorphic proteins mediate evolutionary transitions of structure Proc.Natl.Acad.Sci.USA, 107, 2010
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1CPH
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![BU of 1cph by Molmil](/molmil-images/mine/1cph) | CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | Descriptor: | 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION | Authors: | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | Deposit date: | 1992-10-30 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
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5U4H
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![BU of 5u4h by Molmil](/molmil-images/mine/5u4h) | 1.05 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Acinetobacter baumannii in Covalently Bound Complex with (2R)-2-(phosphonooxy)propanoic Acid. | Descriptor: | (2R)-2-(phosphonooxy)propanoic acid, FORMIC ACID, SODIUM ION, ... | Authors: | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-12-04 | Release date: | 2016-12-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | 1.05 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Acinetobacter baumannii in Covalently Bound Complex with (2R)-2-(phosphonooxy)propanoic Acid. To Be Published
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3KHH
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![BU of 3khh by Molmil](/molmil-images/mine/3khh) | Dpo4 extension ternary complex with a C base opposite the 2-aminofluorene-guanine [AF]G lesion | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-AMINOFLUORENE, 5'-D(*CP*CP*TP*A*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', ... | Authors: | Rechkoblit, O, Malinina, L, Patel, D.J. | Deposit date: | 2009-10-30 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nat.Struct.Mol.Biol., 17, 2010
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3KIF
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![BU of 3kif by Molmil](/molmil-images/mine/3kif) | The crystal structures of two fragments truncated from 5-bladed beta-propeller lectin, tachylectin-2 (Lib1-B7-18 and Lib2-D2-15) | Descriptor: | 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, 5-bladed beta-propeller lectin, SULFATE ION | Authors: | Dym, O, Tawfik, D.S, Yadid, I, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2009-11-02 | Release date: | 2010-04-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Metamorphic proteins mediate evolutionary transitions of structure Proc.Natl.Acad.Sci.USA, 107, 2010
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3KKU
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![BU of 3kku by Molmil](/molmil-images/mine/3kku) | Cruzain in complex with a non-covalent ligand | Descriptor: | 1,2-ETHANEDIOL, Cruzipain, N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide, ... | Authors: | Ferreira, R.S, Eidam, O, Shoichet, B.K. | Deposit date: | 2009-11-06 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors. J.Med.Chem., 53, 2010
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