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PDB: 66 results

7L0N
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Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Snell, G, Czudnochowski, N, Dillen, J, Nix, J.C, Croll, T.I, Corti, D.
Deposit date:2020-12-11
Release date:2021-02-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.
Cell, 184, 2021
5TPY
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Crystal structure of an exonuclease resistant RNA from Zika virus
Descriptor: HEXANE-1,6-DIOL, MAGNESIUM ION, RNA (71-MER)
Authors:Akiyama, B.M, Laurence, H.M, Massey, A.R, Costantino, D.A, Xie, X, Yang, Y, Shi, P.-Y, Nix, J.C, Beckham, J.D, Kieft, J.S.
Deposit date:2016-10-21
Release date:2016-12-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease.
Science, 354, 2016
3S9K
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Crystal structure of the Itk SH2 domain.
Descriptor: CITRIC ACID, Tyrosine-protein kinase ITK/TSK
Authors:Joseph, R.E, Ginder, N.D, Hoy, J.A, Nix, J.C, Fulton, B.D, Honzatko, R.B, Andreotti, A.H.
Deposit date:2011-06-01
Release date:2012-02-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures.
Acta Crystallogr.,Sect.F, 68, 2012
6CDX
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BU of 6cdx by Molmil
High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin
Descriptor: cystine knot (fluoropropylated)
Authors:Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V.
Deposit date:2018-02-09
Release date:2019-08-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1 Å)
Cite:Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.
Nat Commun, 10, 2019
8SDQ
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ATAD2 bromodomain in complex with H4S1phK5ac (res 1-15) ligand
Descriptor: ATPase family AAA domain-containing protein 2, Histone H4
Authors:Malone, K.L, Nix, J.C, Glass, K.C.
Deposit date:2023-04-07
Release date:2024-06-05
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8SDO
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ATAD2 bromodomain in complex with "oncohistone" mutation H4S1CK5ac (res 1-15) ligand
Descriptor: ATPase family AAA domain-containing protein 2, Histone H4
Authors:Malone, K.L, Nix, J.C, Glass, K.C.
Deposit date:2023-04-07
Release date:2024-06-05
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8SDX
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BU of 8sdx by Molmil
ATAD2B bromodomain in complex with histone H4 acetylated at lysine 5 with Serine 1 mutation to Cysteine
Descriptor: ATPase family AAA domain-containing protein 2B, SULFATE ION, histone H4S1CK5ac
Authors:Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C.
Deposit date:2023-04-07
Release date:2024-06-05
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8UK5
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Crystal structure of the bromodomain of human ATAD2B in complex with histone H4S1(ph)K5ac
Descriptor: ATPase family AAA domain-containing protein 2B, Histone H4S1(ph)K5ac
Authors:Montgomery, C, Phillips, M, Nix, J.C, Glass, K.C.
Deposit date:2023-10-12
Release date:2024-06-05
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8UHL
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ATAD2B bromodomain in complex with histone H4 acetylated at lysine 12
Descriptor: ATPase family AAA domain-containing protein 2B, Histone H4
Authors:Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C.
Deposit date:2023-10-09
Release date:2024-06-05
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
6D3P
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BU of 6d3p by Molmil
Crystal structure of an exoribonuclease-resistant RNA from Sweet clover necrotic mosaic virus (SCNMV)
Descriptor: IRIDIUM HEXAMMINE ION, RNA (45-MER)
Authors:Steckelberg, A.-L, Akiyama, B.M, Costantino, D.A, Sit, T.L, Nix, J.C, Kieft, J.S.
Deposit date:2018-04-16
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6OP7
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BU of 6op7 by Molmil
Structure of oxidized VIM-20
Descriptor: ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION
Authors:Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
Deposit date:2019-04-24
Release date:2019-10-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
2QVU
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BU of 2qvu by Molmil
Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Mg2+, I(T)-state
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B.
Deposit date:2007-08-08
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition
J.Biol.Chem., 282, 2007
3VCY
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BU of 3vcy by Molmil
Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Descriptor: GLYCEROL, PHOSPHATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ...
Authors:Bensen, D.C, Rodriguez, S, Nix, J, Cunningham, M.L, Tari, L.W.
Deposit date:2012-01-04
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.925 Å)
Cite:Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Acta Crystallogr.,Sect.F, 68, 2012
3QIL
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BU of 3qil by Molmil
Crystal structure analysis of the clathrin trimerization domain
Descriptor: Clathrin heavy chain 1
Authors:Ybe, J.A, Mishra, S, Nix, J.
Deposit date:2011-01-27
Release date:2012-02-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.92 Å)
Cite:Nuclear localization of clathrin involves a labile helix outside the trimerization domain.
Febs Lett., 587, 2013
3FGH
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BU of 3fgh by Molmil
Human mitochondrial transcription factor A box B
Descriptor: CADMIUM ION, CHLORIDE ION, SODIUM ION, ...
Authors:Gangelhoff, T.A, Mungalachetty, P, Nix, J, Churchill, M.E.A.
Deposit date:2008-12-06
Release date:2009-04-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A
Nucleic Acids Res., 37, 2009
2NO2
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BU of 2no2 by Molmil
Crystal structure of the DLLRKN-containing coiled-coil domain of Huntingtin-interacting protein 1
Descriptor: Huntingtin-interacting protein 1
Authors:Ybe, J.A, Mishra, S, Helms, S, Nix, J.
Deposit date:2006-10-24
Release date:2007-10-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure at 2.8 A of the DLLRKN-containing coiled-coil domain of huntingtin-interacting protein 1 (HIP1) reveals a surface suitable for clathrin light chain binding
J.Mol.Biol., 367, 2007
2NP8
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BU of 2np8 by Molmil
Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors
Descriptor: N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE, SULFATE ION, Serine/threonine-protein kinase 6
Authors:Tari, L.W, Hoffman, I.D, Bensen, D.C, Hunter, M.J, Nix, J, Nelson, K.J, McRee, D.E, Swanson, R.V.
Deposit date:2006-10-26
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
3CQX
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Chaperone Complex
Descriptor: BAG family molecular chaperone regulator 2, Heat shock cognate 71 kDa protein, SODIUM ION, ...
Authors:Xu, Z, Nix, J.C, Misra, S.
Deposit date:2008-04-03
Release date:2008-11-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2
Nat.Struct.Mol.Biol., 15, 2008
7JX3
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BU of 7jx3 by Molmil
Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab domain of monoclonal antibody S2H14, Heavy chain of Fab domain of monoclonal antibody S304, ...
Authors:Snell, G, Czudnochowski, N, Rosen, L.E, Nix, J.C, Corti, D, Veesler, D, Park, Y.J, Walls, A.C, Tortorici, M.A, Cameroni, E, Pinto, D, Beltramello, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-08-26
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell, 183, 2020
5F16
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BU of 5f16 by Molmil
CTA-modified hen egg-white lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:McGlone, C, Nix, J.C, Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
5F14
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BU of 5f14 by Molmil
Structure of native hen egg-white lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:McGlone, C, Nix, J.C, Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.148 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
3QQR
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BU of 3qqr by Molmil
Crystal structure of Parasponia hemoglobin; Differential Heme Coordination is Linked to Quaternary Structure
Descriptor: 1,4-DIETHYLENE DIOXIDE, Non-legume hemoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Kakar, S, Sturms, R, Savage, A, Nix, J.C, Dispirito, A, Hargrove, M.S.
Deposit date:2011-02-16
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structures of Parasponia and Trema hemoglobins: differential heme coordination is linked to quaternary structure.
Biochemistry, 50, 2011
7JJU
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BU of 7jju by Molmil
Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV)
Descriptor: CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ...
Authors:Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold.
Rna, 26, 2020
3D0T
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BU of 3d0t by Molmil
Structure of the BNB domain of the Hsp70 cochaperone Bag2
Descriptor: BAG family molecular chaperone regulator 2
Authors:Xu, Z, Nix, J.C, Devlin, K, Misra, S.
Deposit date:2008-05-02
Release date:2008-11-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2.
Nat.Struct.Mol.Biol., 15, 2008
4GKX
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Crystal structure of a carbohydrate-binding domain
Descriptor: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
Authors:Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013

221051

數據於2024-06-12公開中

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