6KX0
| Crystal structure of SN-101 mAb non-liganded form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain | Authors: | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | Deposit date: | 2019-09-09 | Release date: | 2020-07-29 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.404 Å) | Cite: | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes Chem Sci, 11, 2020
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6KX1
| Crystal structure of SN-101 mAb in complex with MUC1 glycopeptide | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, ... | Authors: | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | Deposit date: | 2019-09-09 | Release date: | 2020-07-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.773 Å) | Cite: | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes Chem Sci, 11, 2020
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8HRH
| SN-131/1B2 anti-MUC1 antibody with a glycopeptide | Descriptor: | 1-ACETYL-L-PROLINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALANINE, ... | Authors: | Wakui, H, Horidome, C, Yao, M, Ose, T, Nishimura, S.-I. | Deposit date: | 2022-12-15 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural and molecular insight into antibody recognition of dynamic neoepitopes in membrane tethered MUC1 of pancreatic cancer cells and secreted exosomes. Rsc Chem Biol, 4, 2023
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