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PDB: 45 件
1NUK
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CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE EPHB2 RECEPTOR TYROSINE KINASE
分子名称: PROTEIN (TYROSINE-PROTEIN KINASE RECEPTOR EPH)
著者Himanen, J.-P, Henkemeyer, M, Nikolov, D.B.
登録日1998-10-13
公開日1999-10-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2.
Nature, 396, 1998
1P8T
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Crystal structure of Nogo-66 Receptor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Reticulon 4 receptor
著者Barton, W.A, Liu, B.P, Tzvetkova, D, Jeffrey, P.D, Fournier, A.E, Sah, D, Cate, R, Strittmatter, S.M, Nikolov, D.B.
登録日2003-05-07
公開日2003-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins
Embo J., 22, 2003
1QWI
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Crystal Structure of E. coli OsmC
分子名称: osmotically inducible protein
著者Lesniak, J, Barton, W.A, Nikolov, D.B.
登録日2003-09-02
公開日2003-12-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC
Protein Sci., 12, 2003
1SHX
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Ephrin A5 ligand structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-A5
著者Himanen, J.P, Barton, W.A, Nikolov, D.B, Jeffrey, P.D.
登録日2004-02-26
公開日2005-04-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005
4PLO
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Crystal Structure of chicken Netrin-1 (LN-LE3) in complex with mouse DCC (FN4-5)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Netrin receptor DCC, ...
著者Xu, K, Nikolov, D.B.
登録日2014-05-18
公開日2014-06-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
4P8S
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Crystal structure of Nogo-receptor-2
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Semavina, M, Saha, N, Kolev, M.V, Giger, R.J, Himanen, J.P, Nikolov, D.B.
登録日2014-04-01
公開日2014-04-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Nogo-receptor-2.
Protein Sci., 2011
4PLM
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Crystal Structure of Chicken Netrin-1 (LN-LE3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Xu, K, Nikolov, D.B.
登録日2014-05-18
公開日2014-06-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
4PLN
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Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ...
著者Xu, K, Nikolov, D.B.
登録日2014-05-18
公開日2014-06-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
4JZC
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Angiopoietin-2 fibrinogen domain TAG mutant
分子名称: Angiopoietin-2
著者Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
登録日2013-04-02
公開日2013-05-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K0V
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Structural basis for angiopoietin-1 mediated signaling initiation
分子名称: Angiopoietin-1, TEK tyrosine kinase variant
著者Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
登録日2013-04-04
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.51 Å)
主引用文献Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
1IIM
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thymidylyltransferase complexed with TTP
分子名称: THYMIDINE-5'-TRIPHOSPHATE, glucose-1-phosphate thymidylyltransferase
著者Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B.
登録日2001-04-23
公開日2001-05-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
4JYO
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Structural basis for angiopoietin-1 mediated signaling initiation
分子名称: Angiopoietin-1, CALCIUM ION
著者Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
登録日2013-03-31
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
1KGY
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Crystal Structure of the EphB2-ephrinB2 complex
分子名称: EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2
著者Himanen, J.P, Rajashankar, K.R, Lackmann, M, Cowan, C.A, Henkemeyer, M, Nikolov, D.B.
登録日2001-11-28
公開日2002-05-28
最終更新日2017-02-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
1IIN
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thymidylyltransferase complexed with UDP-glucose
分子名称: URIDINE-5'-DIPHOSPHATE-GLUCOSE, glucose-1-phosphate thymidylyltransferase
著者Barton, W.A, Lesniak, J, Biggins, J.B, Jeffrey, P.D, Jiang, J, Rajashankar, K.R, Thorson, J.S, Nikolov, D.B.
登録日2001-04-23
公開日2001-05-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
4M4R
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Epha4 ectodomain complex with ephrin a5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4, ...
著者Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
登録日2013-08-07
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4M4P
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Crystal structure of EPHA4 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4
著者Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
登録日2013-08-07
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.081 Å)
主引用文献Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
1MP5
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Y177F VARIANT OF S. ENTERICA RmlA
分子名称: URIDINE-5'-DIPHOSPHATE-GLUCOSE, Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE
著者Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B.
登録日2002-09-11
公開日2002-10-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP4
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W224H VARIANT OF S. ENTERICA RmlA
分子名称: URIDINE-5'-DIPHOSPHATE-GLUCOSE, W224H Variant of S. Enterica RmlA Bound to UDP-Glucose
著者Barton, W.A, Biggins, J.B, Jiang, J, Thorson, J.S, Nikolov, D.B.
登録日2002-09-11
公開日2002-10-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1VTL
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CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA BINDING PROTEIN (TBP)
著者Kim, J.L, Nikolov, D.B, Burley, S.K.
登録日1993-12-17
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Co-Crystal Structure of TBP Recognizing the Minor Groove of a TATA Element
Nature, 365, 1993
3ETP
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The crystal structure of the ligand-binding domain of the EphB2 receptor at 2.0 A resolution
分子名称: Ephrin type-B receptor 2
著者Goldgur, Y, Paavilainen, S, Nikolov, D.B, Himanen, J.P.
登録日2008-10-08
公開日2008-10-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.
Acta Crystallogr.,Sect.F, 65, 2009
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