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PDB: 22 件
5F52
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BU of 5f52 by Molmil
Erwinia chrysanthemi L-asparaginase + Aspartic acid
分子名称: ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, L-asparaginase
著者Nguyen, H.A, Lavie, A.
登録日2015-12-04
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Insight into Substrate Selectivity of Erwinia chrysanthemi l-Asparaginase.
Biochemistry, 55, 2016
5K4H
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BU of 5k4h by Molmil
Wolinella succinogenes L-asparaginase S121 + L-Glutamic acid
分子名称: GLUTAMIC ACID, L-asparaginase
著者Nguyen, H.A, Lave, A.
登録日2016-05-20
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
5K4G
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BU of 5k4g by Molmil
Wolinella succinogenes L-asparaginase S121 + L-aspartic acid, open conformation
分子名称: ASPARTIC ACID, L-asparaginase
著者Nguyen, H.A, Lave, A.
登録日2016-05-20
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
6OPE
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BU of 6ope by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-24
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OF6
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BU of 6of6 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-03-28
公開日2020-06-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
5K3O
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BU of 5k3o by Molmil
Wolinella succinogenes L-asparaginase P121 and L-Aspartic acid
分子名称: ASPARTIC ACID, L-asparaginase
著者Nguyen, H.A, Lave, A.
登録日2016-05-19
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
5K45
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BU of 5k45 by Molmil
Wolinella succinogenes L-asparaginase P121 + L-Glutamic acid
分子名称: GLUTAMIC ACID, L-asparaginase
著者Nguyen, H.A, Lave, A.
登録日2016-05-20
公開日2017-03-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Sci Rep, 7, 2017
6ORD
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BU of 6ord by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-30
公開日2020-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OJ2
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BU of 6oj2 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to the near-cognate 70S A-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-10
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
5HW0
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BU of 5hw0 by Molmil
Erwinia chrysanthemi L-asparaginase + Glutamic acid
分子名称: GLUTAMIC ACID, L-asparaginase
著者Nguyen, H.A, Lavie, A.
登録日2016-01-28
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural Insight into Substrate Selectivity of Erwinia chrysanthemi l-Asparaginase.
Biochemistry, 55, 2016
5I4B
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BU of 5i4b by Molmil
Erwinia chrysanthemi L-asparaginase E63Q +S254N mutation + L-Aspartic acid
分子名称: ASPARTIC ACID, L-asparaginase
著者Nguyen, H.A, Lavie, A.
登録日2016-02-11
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity.
J.Biol.Chem., 291, 2016
5I3Z
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BU of 5i3z by Molmil
Erwinia chrysanthemi L-asparaginase E63Q mutation + Aspartic acid
分子名称: ASPARTIC ACID, L-asparaginase
著者Nguyen, H.A, Lavie, A.
登録日2016-02-11
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity.
J.Biol.Chem., 291, 2016
5I48
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BU of 5i48 by Molmil
Erwinia chrysanthemi L-asparaginase A31I + E63Q mutation + Aspartic acid
分子名称: ASPARTIC ACID, L-asparaginase
著者Nguyen, H.A, Lavie, A.
登録日2016-02-11
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity.
J.Biol.Chem., 291, 2016
8FON
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BU of 8fon by Molmil
Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
登録日2023-01-02
公開日2023-03-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FOM
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BU of 8fom by Molmil
Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
登録日2023-01-02
公開日2023-03-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
分子名称: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
著者Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
登録日2023-01-06
公開日2023-09-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
7U6M
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BU of 7u6m by Molmil
Albumin binding domain fused to a mutant of the Erwinia asparaginase
分子名称: ASPARTIC ACID, L-asparaginase
著者Lavie, A, Nguyen, H.A.
登録日2022-03-04
公開日2022-08-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia.
Haematologica, 108, 2023
9AX8
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BU of 9ax8 by Molmil
70S initiation complex (tRNA-fMet M1, initiation factor 2 + CUG start codon)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
登録日2024-03-06
公開日2024-09-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9CG6
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BU of 9cg6 by Molmil
70S initiation complex (tRNA-fMet M1 + GUG start codon)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
登録日2024-06-28
公開日2024-09-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9CG5
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BU of 9cg5 by Molmil
70S initiation complex (tRNA-fMet M1 + UUG start codon)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
登録日2024-06-28
公開日2024-09-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9CG7
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BU of 9cg7 by Molmil
70S initiation complex (tRNA-fMet M1 + AUG start codon)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
登録日2024-06-28
公開日2024-09-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9AX7
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BU of 9ax7 by Molmil
70S initiation complex (tRNA-fMet M1 + CUG start codon)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
登録日2024-03-06
公開日2024-09-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024

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件を2024-10-30に公開中

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