5H7S
 
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5H7R
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8FY2
 | | E3:PROTAC:target ternary complex structure (VCB/WH244/BCL-2) | | 分子名称: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | 著者 | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Ruben, E, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | 登録日 | 2023-01-25 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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8FY1
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) | | 分子名称: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | | 著者 | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | | 登録日 | 2023-01-25 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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6JX5
 | | Hect domain of AREL1 | | 分子名称: | Apoptosis-resistant E3 ubiquitin protein ligase 1 | | 著者 | Sivaraman, J, Singh, S, Ng, J, Nayak, D. | | 登録日 | 2019-04-22 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro.
J.Biol.Chem., 294, 2019
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5DIN
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8FY0
 | | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) | | 分子名称: | Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... | | 著者 | Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. | | 登録日 | 2023-01-25 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
Nat Commun, 15, 2024
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6JX6
 | | Tetrameric form of Smac | | 分子名称: | Diablo homolog, mitochondrial | | 著者 | Sivaraman, J, Singh, S, Ng, J, Nayak, D. | | 登録日 | 2019-04-22 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro.
J.Biol.Chem., 294, 2019
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8GF5
 | | McrD binds asymmetrically to methyl-coenzyme M reductase improving active site accessibility during assembly | | 分子名称: | 1-THIOETHANESULFONIC ACID, Coenzyme B, FACTOR 430, ... | | 著者 | Joiner, A.M.N, Chadwick, G.L, Nayak, D.D. | | 登録日 | 2023-03-07 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8GF6
 | | Apo-apo MCR assembly intermediate | | 分子名称: | Methyl coenzyme M reductase, subunit D, Methyl-coenzyme M reductase subunit alpha, ... | | 著者 | Joiner, A.M.N, Chadwick, G.L, Nayak, D.D. | | 登録日 | 2023-03-07 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly.
Proc.Natl.Acad.Sci.USA, 120, 2023
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