4TRW
 
 | | Structure of BACE1 complex with a syn-HEA-type inhibitor | | 分子名称: | Beta-secretase 1, L-alpha-glutamyl-L-isoleucyl-N-[(2R,3S)-1-{[(1S)-1-carboxybutyl]amino}-2-hydroxy-5-methylhexan-3-yl]-3-thiophen-2-yl-L-alaninamide | | 著者 | Akaji, K, Teruya, K, Akiyama, T, Sanjho, A, Yamashita, E, Nakagawa, A. | | 登録日 | 2014-06-18 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors
Bioorg.Med.Chem., 23, 2015
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4TRZ
 | | Structure of BACE1 complex with 2-thiophenyl HEA-type inhibitor | | 分子名称: | 2-thiophenyl HEA-type inhibitor, Beta-secretase 1 | | 著者 | Akaji, K, Teruya, K, Akiyama, T, Sanjho, A, Yamashita, E, Nakagawa, A. | | 登録日 | 2014-06-18 | | 公開日 | 2015-07-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors
Bioorg.Med.Chem., 23, 2015
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1MR8
 | | MIGRATION INHIBITORY FACTOR-RELATED PROTEIN 8 FROM HUMAN | | 分子名称: | CALCIUM ION, MIGRATION INHIBITORY FACTOR-RELATED PROTEIN 8 | | 著者 | Ishikawa, K, Nakagawa, A, Tanaka, I, Nishihira, J. | | 登録日 | 1999-04-13 | | 公開日 | 2000-05-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of human MRP8, a member of the S100 calcium-binding protein family, by MAD phasing at 1.9 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
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1ODD
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4TWW
 | | Structure of SARS-3CL protease complex with a Bromobenzoyl (S,R)-N-decalin type inhibitor | | 分子名称: | (2S)-2-({[(3S,4aR,8aS)-2-(4-bromobenzoyl)decahydroisoquinolin-3-yl]methyl}amino)-3-(1H-imidazol-5-yl)propanal, 3C-like proteinase | | 著者 | Akaji, K, Teruya, K, Shimamoto, Y, Sanjho, A, Yamashita, E, Nakagawa, A. | | 登録日 | 2014-07-02 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Fused-ring structure of decahydroisoquinolin as a novel scaffold for SARS 3CL protease inhibitors
Bioorg.Med.Chem., 23, 2015
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5AZP
 | | Crystal structure of a membrane protein from Pseudomonas aeruginosa | | 分子名称: | (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, ACETATE ION, FORMIC ACID, ... | | 著者 | Yonehara, R, Yamashita, E, Nakagawa, A. | | 登録日 | 2015-10-21 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa.
Proteins, 84, 2016
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5AZO
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5AZS
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6LYC
 | | Crystal structure of the NOD SIRPa complex with D4-2 | | 分子名称: | ACETIC ACID, D4-2, SIRPa of the NOD mouse strain | | 著者 | Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T. | | 登録日 | 2020-02-14 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy.
Cell Chem Biol, 27, 2020
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7XBQ
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7X8V
 | | Cooperative regulation of PBI1 and MAPKs controls WRKY45 transcription factor in rice immunity | | 分子名称: | Os01g0156300 protein | | 著者 | Ichimaru, K, Harada, K, Yamaguchi, K, Shigeta, S, Shimada, K, Ishikawa, K, Inoue, K, Nishio, Y, Yoshimura, S, Inoue, H, Yamashita, E, Fujiwara, T, Nakagawa, A, Kojima, C, Kawasaki, T. | | 登録日 | 2022-03-15 | | 公開日 | 2022-04-06 | | 最終更新日 | 2022-06-01 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Cooperative regulation of PBI1 and MAPKs controls WRKY45 transcription factor in rice immunity.
Nat Commun, 13, 2022
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4TRY
 | | Structure of BACE1 complex with a HEA-type inhibitor | | 分子名称: | Beta-secretase 1, GLU-ILE-TIH-THC-NVA | | 著者 | Akaji, K, Teruya, K, Akiyama, T, Sanjho, A, Yamashita, E, Nakagawa, A. | | 登録日 | 2014-06-18 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure of BACE1 complex with an anti-HMC-type inhibitor
to be published
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4NI0
 | | Quaternary R3 CO-liganded hemoglobin structure in complex with a thiol containing compound | | 分子名称: | 5-[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | | 著者 | Safo, M.K, Meadows, J, Ko, T.-P, Nakagawa, A, Zapol, W. | | 登録日 | 2013-11-05 | | 公開日 | 2014-08-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling.
Acs Chem.Biol., 9, 2014
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4NI1
 | | Quaternary R CO-liganded hemoglobin structure in complex with a thiol containing compound | | 分子名称: | 5-[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | | 著者 | Safo, M.K, Meadows, J, Ko, T.-P, Nakagawa, A, Zapol, W. | | 登録日 | 2013-11-05 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling.
Acs Chem.Biol., 9, 2014
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5X6U
 | | Crystal structure of human heteropentameric complex | | 分子名称: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | | 著者 | Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. | | 登録日 | 2017-02-23 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the assembly of the Ragulator-Rag GTPase complex.
Nat Commun, 8, 2017
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5X6V
 | | Crystal structure of human heteroheptameric complex | | 分子名称: | ACETATE ION, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ... | | 著者 | Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. | | 登録日 | 2017-02-23 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the assembly of the Ragulator-Rag GTPase complex.
Nat Commun, 8, 2017
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5ZFG
 | | Crystal structure of a diazinon-metabolizing glutathione S-transferase in the silkworm, Bombyx mori | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Glutathione S-transferase | | 著者 | Yamamoto, K, Higashiura, A, Nakagawa, A. | | 登録日 | 2018-03-06 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Characterisation of a diazinon-metabolising glutathione S-transferase in the silkworm Bombyx mori by X-ray crystallography and genome editing analysis.
Sci Rep, 8, 2018
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5ZF1
 | | Molecular structure of a novel 5,10-methylenetetrahydrofolate dehydrogenase from the silkworm, Bombyx mori | | 分子名称: | 1,2-ETHANEDIOL, 5,10-methylenetetrahydrofolate dehydrogenase, SULFATE ION | | 著者 | Haque, R, Higashiura, A, Nakagawa, A, Yamamoto, K. | | 登録日 | 2018-03-02 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular structure of a 5,10-methylenetetrahydrofolate dehydrogenase from the silkwormBombyx mori.
FEBS Open Bio, 9, 2019
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2HI7
 | | Crystal structure of DsbA-DsbB-ubiquinone complex | | 分子名称: | Disulfide bond formation protein B, Thiol:disulfide interchange protein dsbA, UBIQUINONE-1, ... | | 著者 | Inaba, K, Murakami, S, Suzuki, M, Nakagawa, A, Yamashita, E, Okada, K, Ito, K. | | 登録日 | 2006-06-29 | | 公開日 | 2006-12-05 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal Structure of the DsbB-DsbA Complex Reveals a Mechanism of Disulfide Bond Generation
Cell(Cambridge,Mass.), 127, 2006
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5X70
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5X6X
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5X6Z
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5X6Y
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5X71
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1GCJ
 | | N-TERMINAL FRAGMENT OF IMPORTIN-BETA | | 分子名称: | IMPORTIN BETA | | 著者 | Lee, S.J, Imamoto, N, Sakai, H, Nakagawa, A, Kose, S, Koike, M, Yamamoto, M, Kumasaka, T, Yoneda, Y, Tsukihara, T. | | 登録日 | 2000-07-31 | | 公開日 | 2000-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport.
J.Mol.Biol., 302, 2000
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