6FTY
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![BU of 6fty by Molmil](/molmil-images/mine/6fty) | COMPLEMENT FACTOR D COMPLEXED WITH COMPOUND 5 | 分子名称: | 4-[[(5~{S},7~{R})-3-azanyl-1-adamantyl]carbonylamino]-1~{H}-indole-2-carboxamide, Complement factor D, GLYCEROL | 著者 | Ostermann, N. | 登録日 | 2018-02-26 | 公開日 | 2018-06-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D. ACS Med Chem Lett, 9, 2018
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4ZW3
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4ZX4
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6FXH
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2ZBP
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![BU of 2zbp by Molmil](/molmil-images/mine/2zbp) | Crystal structure of ribosomal protein L11 methyltransferase from Thermus thermophilus in complex with S-adenosyl-L-methionine | 分子名称: | Ribosomal protein L11 methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Kaminishi, T, Sakai, H, Takemoto-Hori, C, Terada, T, Nakagawa, N, Maoka, N, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-10-26 | 公開日 | 2008-11-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of ribosomal protein L11 methyltransferase from Thermus thermophilus To be Published
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5A7O
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![BU of 5a7o by Molmil](/molmil-images/mine/5a7o) | Crystal structure of human JMJD2A in complex with compound 42 | 分子名称: | 1,2-ETHANEDIOL, 2-[5-(2-methoxyethanoylamino)-2-oxidanyl-phenyl]pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, ... | 著者 | Nowak, R, Velupillai, S, Krojer, T, Gileadi, C, Johansson, C, Korczynska, M, Le, D.D, Younger, N, Gregori-Puigjane, E, Tumber, A, Iwasa, E, Pollock, S.B, Ortiz Torres, I, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Shoichet, B.K, Fujimori, D.G, Oppermann, U. | 登録日 | 2015-07-09 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Docking and Linking of Fragments to Discover Jumonji Histone Demethylase Inhibitors. J.Med.Chem., 59, 2016
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6FZP
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![BU of 6fzp by Molmil](/molmil-images/mine/6fzp) | PPAR gamma complex. | 分子名称: | (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 著者 | Rochel, N, Beji, S. | 登録日 | 2018-03-15 | 公開日 | 2019-02-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors. Nat Commun, 10, 2019
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2ZCF
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![BU of 2zcf by Molmil](/molmil-images/mine/2zcf) | Mutational study on Alpha-Gln90 of Fe-type nitrile hydratase from Rhodococcus sp. N771 | 分子名称: | FE (III) ION, MAGNESIUM ION, Nitrile hydratase subunit alpha, ... | 著者 | Takarada, H, Kawano, Y, Hashimoto, K, Nakayama, H, Ueda, S, Yohda, M, Kamiya, N, Dohmae, N, Maeda, M, Odaka, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-11-08 | 公開日 | 2007-11-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Mutational study on alphaGln90 of Fe-type nitrile hydratase from Rhodococcus sp. N771 Biosci.Biotechnol.Biochem., 70, 2006
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4ZUD
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![BU of 4zud by Molmil](/molmil-images/mine/4zud) | Crystal Structure of Human Angiotensin Receptor in Complex with Inverse Agonist Olmesartan at 2.8A resolution. | 分子名称: | Chimera protein of Soluble cytochrome b562 and Type-1 angiotensin II receptor, Olmesartan | 著者 | Zhang, H, Unal, H, Desnoyer, R, Han, G.W, Patel, N, Katritch, V, Karnik, S.S, Cherezov, V, Stevens, R.C, GPCR Network (GPCR) | 登録日 | 2015-05-15 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. J.Biol.Chem., 290, 2015
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4ZWC
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![BU of 4zwc by Molmil](/molmil-images/mine/4zwc) | Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | 著者 | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | 登録日 | 2015-05-19 | 公開日 | 2015-07-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular basis of ligand recognition and transport by glucose transporters Nature, 526, 2015
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6G3S
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![BU of 6g3s by Molmil](/molmil-images/mine/6g3s) | Structure of tellurium-centred Anderson-Evans polyoxotungstate (TEW) bound to the nucleotide binding domain of HSP70. Second structure of two TEW-HSP70 structures deposited. | 分子名称: | 6-tungstotellurate(VI), ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A, ... | 著者 | Mac Sweeney, A, Chambovey, A, Wicki, M, Mueller, M, Artico, N, Lange, R, Bijelic, A, Breibeck, J, Rompel, A. | 登録日 | 2018-03-26 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms. PLoS ONE, 13, 2018
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6FZF
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![BU of 6fzf by Molmil](/molmil-images/mine/6fzf) | PPAR mutant complex | 分子名称: | (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 著者 | Rochel, N. | 登録日 | 2018-03-14 | 公開日 | 2019-02-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors. Nat Commun, 10, 2019
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4ZW9
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![BU of 4zw9 by Molmil](/molmil-images/mine/4zw9) | Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | 著者 | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | 登録日 | 2015-05-19 | 公開日 | 2015-07-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | 主引用文献 | Molecular basis of ligand recognition and transport by glucose transporters Nature, 526, 2015
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5A2L
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![BU of 5a2l by Molmil](/molmil-images/mine/5a2l) | Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MODIFIED ANTIGEN TN, ... | 著者 | Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. | 登録日 | 2015-05-20 | 公開日 | 2015-06-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54, 2015
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6G3R
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![BU of 6g3r by Molmil](/molmil-images/mine/6g3r) | Structure of tellurium-centred Anderson-Evans polyoxotungstate (TEW) bound to the nucleotide binding domain of HSP70. Structure one of two TEW-HSP70 structures deposited. | 分子名称: | 6-tungstotellurate(VI), ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A, ... | 著者 | Mac Sweeney, A, Chambovey, A, Wicki, M, Mueller, M, Artico, N, Lange, R, Bijelic, A, Breibeck, J, Rompel, A. | 登録日 | 2018-03-26 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms. PLoS ONE, 13, 2018
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6GAW
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![BU of 6gaw by Molmil](/molmil-images/mine/6gaw) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome. | 分子名称: | 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ... | 著者 | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | 登録日 | 2018-04-13 | 公開日 | 2018-08-22 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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8KB0
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![BU of 8kb0 by Molmil](/molmil-images/mine/8kb0) | Crystal structure of 01JD-AEAIIVAMV | 分子名称: | Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
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8KB1
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![BU of 8kb1 by Molmil](/molmil-images/mine/8kb1) | Crystal structure of 11JD | 分子名称: | Beta2-microglobulin, MHC class I antigen, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
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6FW0
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![BU of 6fw0 by Molmil](/molmil-images/mine/6fw0) | Crystal structure of human monoamine oxidase B (MAO B) in complex with chlorophenyl-chromone-carboxamide | 分子名称: | Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Reis, J, Manzella, N, Cagide, F, Mialet-Perez, J, Uriarte, E, Parini, A, Borges, F, Binda, C. | 登録日 | 2018-03-05 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis. J. Med. Chem., 61, 2018
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6FWC
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![BU of 6fwc by Molmil](/molmil-images/mine/6fwc) | Crystal structure of human monoamine oxidase B (MAO B) in complex with fluorophenyl-chromone-carboxamide | 分子名称: | Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Reis, J, Manzella, N, Cagide, F, Mialet-Perez, J, Uriarte, E, Parini, A, Borges, F, Binda, C. | 登録日 | 2018-03-06 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis. J. Med. Chem., 61, 2018
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8TNE
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![BU of 8tne by Molmil](/molmil-images/mine/8tne) | Crystal structure of bacterial pectin methylesterase Pme8A from rumen Butyrivibrio | 分子名称: | 1,2-ETHANEDIOL, Pectinesterase | 著者 | Carbone, V, Reilly, K, Sang, C, Schofield, L, Ronimus, R, Kelly, W.J, Attwood, G.T, Palevich, N. | 登録日 | 2023-08-01 | 公開日 | 2023-08-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio . Int J Mol Sci, 24, 2023
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8SYF
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![BU of 8syf by Molmil](/molmil-images/mine/8syf) | Homology model of Acto-HMM complex in ADP-state. Chicken smooth muscle HMM and chicken pectoralis actin | 分子名称: | Actin, alpha skeletal muscle, Myosin light polypeptide 6, ... | 著者 | Hojjatian, A, Taylor, D.W, Daneshparvar, N, Trybus, K.M, Taylor, K.A. | 登録日 | 2023-05-25 | 公開日 | 2023-08-30 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (19 Å) | 主引用文献 | Double-headed binding of myosin II to F-actin shows the effect of strain on head structure. J.Struct.Biol., 215, 2023
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5A4N
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8TMS
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![BU of 8tms by Molmil](/molmil-images/mine/8tms) | Crystal structure of bacterial pectin methylesterase PmeC2 from rumen Butyrivibrio | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Pectinesterase | 著者 | Carbone, V, Reilly, K, Sang, C, Schofield, L, Ronimus, R, Kelly, W.J, Attwood, G.T, Palevich, N. | 登録日 | 2023-07-30 | 公開日 | 2023-08-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio . Int J Mol Sci, 24, 2023
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6G5N
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![BU of 6g5n by Molmil](/molmil-images/mine/6g5n) | Crystal structure of human SP100 in complex with bromodomain-focused fragment XS039818e 1-(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine | 分子名称: | (3-phenyl-1,2,4-oxadiazol-5-yl)methanamine, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Talon, R.P.H, Krojer, T, Tallant, C, Nunez-Alonso, G, Fairhead, M, Szykowska, A, Collins, P, Pearce, N.M, Ng, J, MacLean, E, Wright, N, Douangamath, A, Brandao-Neto, J, Burgess-Brown, N, Huber, K, Knapp, S, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F. | 登録日 | 2018-03-29 | 公開日 | 2018-04-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.765 Å) | 主引用文献 | Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces Biorxiv, 2018
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