6LYM
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![BU of 6lym by Molmil](/molmil-images/mine/6lym) | Crystal structure of D657A mutant of formylglycinamidine synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-14 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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6LYO
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![BU of 6lyo by Molmil](/molmil-images/mine/6lyo) | Crystal Structure of H296A mutant of Formylglycinamidine Synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-15 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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6Y3I
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![BU of 6y3i by Molmil](/molmil-images/mine/6y3i) | NMR solution structure of the hazelnut allergen Cor a 1.0402 | 分子名称: | Major allergen variant Cor a 1.0402 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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6LYK
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![BU of 6lyk by Molmil](/molmil-images/mine/6lyk) | Crystal Structure of R1263A mutant of Formylglycinamidine Synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-14 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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1E2G
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![BU of 1e2g by Molmil](/molmil-images/mine/1e2g) | Human thymidylate kinase complexed with ADP, TDP and a magnesium-ion | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | 著者 | Ostermann, N, Schlichting, I, Brundiers, R, Konrad, M, Reinstein, J, Veit, T, Goody, R.S, Lavie, A. | 登録日 | 2000-05-22 | 公開日 | 2001-05-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights Into the Phosphoryltransfer Mechanism of Human Thymidylate Kinase Gained from Crystal Structures of Enzyme Complexes Along the Reaction Coordinate Structure, 8, 2000
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6LYL
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![BU of 6lyl by Molmil](/molmil-images/mine/6lyl) | Crystal structure of S1052D mutant of Formylglycinamidine synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-14 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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5Y3B
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![BU of 5y3b by Molmil](/molmil-images/mine/5y3b) | |
6LXV
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![BU of 6lxv by Molmil](/molmil-images/mine/6lxv) | Cryo-EM structure of phosphoketolase from Bifidobacterium longum | 分子名称: | CALCIUM ION, Phosphoketolase, THIAMINE DIPHOSPHATE | 著者 | Nakata, K, Miyazaki, N, Yamaguchi, H, Hirose, M, Miyano, H, Mizukoshi, T, Kashiwagi, T, Iwasaki, K. | 登録日 | 2020-02-12 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | High-resolution structure of phosphoketolase from Bifidobacterium longum determined by cryo-EM single-particle analysis. J.Struct.Biol., 214, 2022
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6M6I
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![BU of 6m6i by Molmil](/molmil-images/mine/6m6i) | Structure of HSV2 B-capsid portal vertex | 分子名称: | Coiled coils chain 1, Coiled coils chain 2, Major capsid protein, ... | 著者 | Wang, X.X, Wang, N. | 登録日 | 2020-03-14 | 公開日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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6M7D
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![BU of 6m7d by Molmil](/molmil-images/mine/6m7d) | |
1EAR
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![BU of 1ear by Molmil](/molmil-images/mine/1ear) | Crystal structure of Bacillus pasteurii UreE at 1.7 A. Type II crystal form. | 分子名称: | UREASE ACCESSORY PROTEIN UREE, ZINC ION | 著者 | Remaut, H, Safarov, N, Ciurli, S, Van Beeumen, J. | 登録日 | 2001-07-16 | 公開日 | 2002-01-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis for Ni2+ Transport and Assembly of the Urease Active Site by the Metallochaperone Uree from Bacillus Pasteurii J.Biol.Chem., 276, 2001
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6LQA
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![BU of 6lqa by Molmil](/molmil-images/mine/6lqa) | voltage-gated sodium channel Nav1.5 with quinidine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Quinidine, Sodium channel protein type 5 subunit alpha | 著者 | Yan, N, Li, Z, Pan, X, Huang, G. | 登録日 | 2020-01-13 | 公開日 | 2021-03-24 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Na v 1.5 by the Antiarrhythmic Drug Quinidine*. Angew.Chem.Int.Ed.Engl., 60, 2021
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6M6H
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![BU of 6m6h by Molmil](/molmil-images/mine/6m6h) | Structure of HSV2 C-capsid portal vertex | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Wang, X.X, Wang, N. | 登録日 | 2020-03-14 | 公開日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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6M6G
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![BU of 6m6g by Molmil](/molmil-images/mine/6m6g) | Structure of HSV2 viron capsid portal vertex | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Coiled coils, ... | 著者 | Wang, X.X, Wang, N. | 登録日 | 2020-03-14 | 公開日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (5.39 Å) | 主引用文献 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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1EB0
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![BU of 1eb0 by Molmil](/molmil-images/mine/1eb0) | Crystal structure of Bacillus pasteurii UreE at 1.85 A, phased by SIRAS. Type I crystal form. | 分子名称: | UREASE ACCESSORY PROTEIN UREE, ZINC ION | 著者 | Remaut, H, Safarov, N, Ciurli, S, Van Beeumen, J. | 登録日 | 2001-07-17 | 公開日 | 2002-01-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Basis for Ni2+ Transport and Assembly of the Urease Active Site by the Metallochaperone Uree from Bacillus Pasteurii J.Biol.Chem., 276, 2001
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6M05
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![BU of 6m05 by Molmil](/molmil-images/mine/6m05) | Trimolecular G-quadruplex | 分子名称: | DNA (5'-D(*GP*TP*TP*AP*GP*G)-3') | 著者 | Jing, H.T, Fu, W.Q, Zhang, N. | 登録日 | 2020-02-20 | 公開日 | 2021-01-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na+ solution with a moderate K+ tolerance. Nucleic Acids Res., 49, 2021
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2VZ0
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![BU of 2vz0 by Molmil](/molmil-images/mine/2vz0) | Pteridine Reductase 1 (PTR1) from Trypanosoma Brucei in complex with NADP and DDD00066641 | 分子名称: | 6-(4-methylphenyl)quinazoline-2,4-diamine, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE | 著者 | Robinson, D.A, Thompson, S, Sienkiewicz, N, Fairlamb, A.H. | 登録日 | 2008-07-29 | 公開日 | 2009-09-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Development and Validation of a Cytochrome C Coupled Assay for Pteridine Reductase 1 and Dihydrofolate Reductase. Anal.Biochem., 396, 2010
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6MGF
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![BU of 6mgf by Molmil](/molmil-images/mine/6mgf) | untagged, wild-type LptB in complex with ADP | 分子名称: | (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-ben zopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, ... | 著者 | Mandler, M.D, Owens, T.W, Ruiz, N, Kahne, D. | 登録日 | 2018-09-13 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.982 Å) | 主引用文献 | Bypassing the requirement for coupling of ATP binding and hydrolysis in the lipopolysaccharide ABC transporte not published
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6YMN
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6MJ3
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![BU of 6mj3 by Molmil](/molmil-images/mine/6mj3) | CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 Fc Fragment-Fc-GAMMA RECEPTOR III complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Igg1 Fc, ... | 著者 | Gohain, N, Tolbert, W.D, Pazgier, M. | 登録日 | 2018-09-20 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques. Front Immunol, 13, 2022
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1E3K
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![BU of 1e3k by Molmil](/molmil-images/mine/1e3k) | Human Progesteron Receptor Ligand Binding Domain in complex with the ligand metribolone (R1881) | 分子名称: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, PROGESTERONE RECEPTOR | 著者 | Matias, P.M, Donner, P, Coelho, R, Thomaz, M, Peixoto, C, Macedo, S, Otto, N, Joschko, S, Scholz, P, Wegg, A, Basler, S, Schafer, M, Egner, U, Carrondo, M.A. | 登録日 | 2000-06-19 | 公開日 | 2001-06-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J. Biol. Chem., 275, 2000
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1E3G
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![BU of 1e3g by Molmil](/molmil-images/mine/1e3g) | Human Androgen Receptor Ligand Binding in complex with the ligand metribolone (R1881) | 分子名称: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, ANDROGEN RECEPTOR | 著者 | Matias, P.M, Donner, P, Coelho, R, Thomaz, M, Peixoto, C, Macedo, S, Otto, N, Joschko, S, Scholz, P, Wegg, A, Basler, S, Schafer, M, Ruff, M, Egner, U, Carrondo, M.A. | 登録日 | 2000-06-14 | 公開日 | 2001-06-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J. Biol. Chem., 275, 2000
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6YGU
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![BU of 6ygu by Molmil](/molmil-images/mine/6ygu) | Crystal structure of the minimal Mtr4-Red1 complex (single chain) from Chaetomium thermophilum | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ATP dependent RNA helicase (Dob1)-like protein, ... | 著者 | Dobrev, N, Ahmed, Y.L, Sinning, I. | 登録日 | 2020-03-27 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nat Commun, 12, 2021
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6YFV
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![BU of 6yfv by Molmil](/molmil-images/mine/6yfv) | Crystal structure of Mtr4-Red1 minimal complex from Chaetomium thermophilum | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATP dependent RNA helicase (Dob1)-like protein, Red1, ... | 著者 | Dobrev, N, Ahmed, Y.L, Sinning, I. | 登録日 | 2020-03-26 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-23 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nat Commun, 12, 2021
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1DLR
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![BU of 1dlr by Molmil](/molmil-images/mine/1dlr) | METHOTREXATE-RESISTANT VARIANTS OF HUMAN DIHYDROFOLATE REDUCTASE WITH SUBSTITUTION OF LEUCINE 22: KINETICS, CRYSTALLOGRAPHY AND POTENTIAL AS SELECTABLE MARKERS | 分子名称: | 6-(2,5-DIMETHOXY-BENZYL)-5-METHYL-PYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. | 登録日 | 1995-01-25 | 公開日 | 1995-04-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers. J.Biol.Chem., 270, 1995
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