2VZ0

Pteridine Reductase 1 (PTR1) from Trypanosoma Brucei in complex with NADP and DDD00066641

Summary for 2VZ0

Entry DOI	10.2210/pdb2vz0/pdb
Related	2C7V
Descriptor	PTERIDINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 6-(4-methylphenyl)quinazoline-2,4-diamine, ... (4 entities in total)
Functional Keywords	oxidoreductase, short-chain dehydrogenase/reductase, trypanosomatids, pteridine reductase
Biological source	TRYPANOSOMA BRUCEI BRUCEI
Total number of polymer chains	4
Total formula weight	117968.58
Authors	Robinson, D.A.,Thompson, S.,Sienkiewicz, N.,Fairlamb, A.H. (deposition date: 2008-07-29, release date: 2009-09-22, Last modification date: 2023-12-13)
Primary citation	Shanks, E.J.,Ong, H.B.,Robinson, D.A.,Thompson, S.,Sienkiewicz, N.,Fairlamb, A.H.,Frearson, J.A. Development and Validation of a Cytochrome C Coupled Assay for Pteridine Reductase 1 and Dihydrofolate Reductase. Anal.Biochem., 396:194-, 2010 Cited by PubMed: 19748480 DOI: 10.1016/J.AB.2009.09.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation