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PDB: 51 results
4X8Q
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BU of 4x8q by Molmil
X-ray crystal structure of AlkD2 from Streptococcus mutans
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Mullins, E.A, Shi, R, Eichman, B.F.
Deposit date:2014-12-10
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.729 Å)
Cite:A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases.
Plos One, 10, 2015
5KUB
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BU of 5kub by Molmil
Bacillus cereus DNA glycosylase AlkD bound to 7-methylguanine nucleobase and DNA containing an oxocarbenium-intermediate analog
Descriptor: 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, DNA (5'-D(*CP*CP*CP*GP*AP*(NRI)P*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*CP*TP*CP*GP*GP*G)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2016-07-13
Release date:2016-09-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A Catalytic Role for C-H/ pi Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD.
J.Am.Chem.Soc., 138, 2016
4EU9
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BU of 4eu9 by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6-R228E) in complex with CoA and a covalent glutamyl-CoA thioester adduct
Descriptor: CHLORIDE ION, COENZYME A, Succinyl-CoA:acetate coenzyme A transferase
Authors:Mullins, E.A, Kappock, T.J.
Deposit date:2012-04-25
Release date:2012-10-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.479 Å)
Cite:Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
Biochemistry, 51, 2012
4EUA
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BU of 4eua by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6-R228E) in complex with CoA (anomalous dataset)
Descriptor: CHLORIDE ION, COENZYME A, Succinyl-CoA:acetate coenzyme A transferase
Authors:Mullins, E.A, Kappock, T.J.
Deposit date:2012-04-25
Release date:2012-10-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
Biochemistry, 51, 2012
4EU7
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BU of 4eu7 by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA and citrate
Descriptor: CHLORIDE ION, CITRIC ACID, COENZYME A, ...
Authors:Mullins, E.A, Kappock, T.J.
Deposit date:2012-04-25
Release date:2012-10-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
Biochemistry, 51, 2012
4EU4
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BU of 4eu4 by Molmil
Succinyl-CoA: acetate CoA-transferase (AarCH6) in complex with CoA (hexagonal lattice)
Descriptor: CHLORIDE ION, COENZYME A, SULFATE ION, ...
Authors:Mullins, E.A, Kappock, T.J.
Deposit date:2012-04-25
Release date:2012-10-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
Biochemistry, 51, 2012
4EU3
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BU of 4eu3 by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with citrate (subunit B) or unliganded (subunit A)
Descriptor: CHLORIDE ION, CITRIC ACID, Succinyl-CoA:acetate coenzyme A transferase
Authors:Mullins, E.A, Kappock, T.J.
Deposit date:2012-04-25
Release date:2012-10-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases.
Biochemistry, 51, 2012
8UCW
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BU of 8ucw by Molmil
Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Chazin, W.C, Eichman, B.F.
Deposit date:2023-09-27
Release date:2023-10-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCV
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BU of 8ucv by Molmil
Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Chazin, W.C, Eichman, B.F.
Deposit date:2023-09-27
Release date:2023-10-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCU
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BU of 8ucu by Molmil
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-09-27
Release date:2023-10-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
5UUG
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BU of 5uug by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing an abasic site (9-mer product complex)
Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*GP*CP*AP*(ORP)P*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*TP*GP*CP*C)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2017-02-16
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.712 Å)
Cite:Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Nat. Chem. Biol., 13, 2017
5UUF
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BU of 5uuf by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing an abasic site (12-mer product complex)
Descriptor: DNA (5'-D(*CP*CP*CP*CP*AP*(ORP)P*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*CP*TP*TP*TP*GP*GP*GP*G)-3'), DNA-7-methylguanine glycosylase, ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2017-02-16
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.612 Å)
Cite:Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Nat. Chem. Biol., 13, 2017
5UUJ
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BU of 5uuj by Molmil
Streptomyces sahachiroi DNA glycosylase AlkZ
Descriptor: AlkZ
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2017-02-16
Release date:2017-04-12
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Structure of a DNA glycosylase that unhooks interstrand cross-links.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UUH
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BU of 5uuh by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing a fluorinated abasic site (9-mer product complex)
Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*GP*CP*AP*(ORF)P*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*TP*GP*CP*C)-3'), ...
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2017-02-16
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.569 Å)
Cite:Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Nat. Chem. Biol., 13, 2017
8G9L
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BU of 8g9l by Molmil
DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G9O
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BU of 8g9o by Molmil
Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G9N
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BU of 8g9n by Molmil
Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G9F
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BU of 8g9f by Molmil
Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G99
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BU of 8g99 by Molmil
Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6H
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BU of 8v6h by Molmil
DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.11 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
5E5H
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BU of 5e5h by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6) bound to acetate and degradation products from the acetyl-CoA analogue dethiaacetyl-CoA
Descriptor: ACETATE ION, ACETYL GROUP, CHLORIDE ION, ...
Authors:Mullins, E.A, Kappock, T.J.
Deposit date:2015-10-08
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase.
Front Chem, 4, 2016
8V5N
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BU of 8v5n by Molmil
Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8.56 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6I
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BU of 8v6i by Molmil
DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (14.06 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6G
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BU of 8v6g by Molmil
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-12-01
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (11.16 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5O
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BU of 8v5o by Molmil
Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-11-30
Release date:2023-12-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8.99 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024

 

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