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PDB: 4 results

5KQ4
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BU of 5kq4 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2 and synthetic cap analog
Descriptor: Proline-rich nuclear receptor coactivator 2, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate, mRNA decapping complex subunit 2, ...
Authors:Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
Deposit date:2016-07-05
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
5KQ1
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BU of 5kq1 by Molmil
Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2
Descriptor: Proline-rich nuclear receptor coactivator 2, mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
Authors:Mugridge, J.S, Ziemniak, M, Jemielity, J, Gross, J.D.
Deposit date:2016-07-05
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Nat.Struct.Mol.Biol., 23, 2016
6AM0
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BU of 6am0 by Molmil
Crystal structure of K. lactis Edc1-Dcp1-Dcp2-Edc3 decapping complex with synthetic cap substrate analog
Descriptor: KLLA0A01474p, KLLA0A11308p, KLLA0E01827p, ...
Authors:Mugridge, J.S, Gross, J.D.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.
Nat Commun, 9, 2018
9DW6
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BU of 9dw6 by Molmil
Crystal structure of SARS-CoV-2 main protease (Mpro) C145A mutant in complex with peptide from human tRNA methyltransferase TRMT1
Descriptor: 3C-like proteinase nsp5, CHLORIDE ION, GLYCEROL, ...
Authors:D'Oliviera, A, Mugridge, J.S.
Deposit date:2024-10-08
Release date:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease.
Elife, 2023

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