2YAZ
 
 | | The Crystal Structure of Leishmania major dUTPase in complex dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DUTPASE, MAGNESIUM ION, ... | | 著者 | Hemsworth, G.R, Moroz, O.V, Fogg, M.J, Scott, B, Bosch-Navarrete, C, Gonzalez-Pacanowska, D, Wilson, K.S. | | 登録日 | 2011-02-25 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
J.Biol.Chem., 286, 2011
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8QF2
 | | Beta-L-Arabinofurano-cyclitol Aziridines are Cysteine-directed Broad-spectrum Inhibitors and Activity-based Probes for Retaining Beta-L-arabinofuranosidases | | 分子名称: | (1~{S},2~{S},3~{S},4~{R})-4-azanyl-3-(hydroxymethyl)cyclopentane-1,2-diol, Non-reducing end beta-L-arabinofuranosidase, ZINC ION | | 著者 | Borlandelli, V, Offen, W.A, Moroz, O, Nin-Hill, A, McGregor, N, Binkhorst, L, Armstrong, Z, Ishiwata, A, Artola, M, Rovira, C, Davies, G.J, Overkleeft, H. | | 登録日 | 2023-09-02 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | beta-l- Arabino furano-cyclitol Aziridines Are Covalent Broad-Spectrum Inhibitors and Activity-Based Probes for Retaining beta-l-Arabinofuranosidases.
Acs Chem.Biol., 18, 2023
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9F5H
 | | Crystal structure of MGAT5 bump-and-hole mutant in complex with UDP and M592 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, ... | | 著者 | Liu, Y, Bineva-Todd, G, Meek, R, Mazo, L, Piniello, B, Moroz, O.V, Begum, N, Roustan, C, Tomita, S, Kjaer, S, Rovira, C, Davies, G.J, Schumann, B. | | 登録日 | 2024-04-28 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | A Bioorthogonal Precision Tool for Human N -Acetylglucosaminyltransferase V.
J.Am.Chem.Soc., 146, 2024
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6SAO
 | | Structural and functional characterisation of three novel fungal amylases with enhanced stability and pH tolerance | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | | 著者 | Roth, C, Moroz, O.V, Turkenburg, J.P, Blagova, E, Waterman, J, Ariza, A, Ming, L, Tianqi, S, Andersen, C, Davies, G.J, Wilson, K.S. | | 登録日 | 2019-07-17 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance.
Int J Mol Sci, 20, 2019
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6SAU
 | | Structural and functional characterisation of three novel fungal amylases with enhanced stability and pH tolerance. | | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, CALCIUM ION, SODIUM ION, ... | | 著者 | Roth, C, Moroz, O.V, Turkenburg, J.P, Blagova, E, Waterman, J, Ariza, A, Ming, L, Tinaqi, S, Andersen, C, Davies, G.J, Wilson, K.S. | | 登録日 | 2019-07-17 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance.
Int J Mol Sci, 20, 2019
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7NSN
 | | Multi-domain GH92 alpha-1,2-mannosidase from Neobacillus novalis: mannoimidazole complex | | 分子名称: | (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Kolaczkowski, B.M, Moroz, O.V, Blagova, E, Davies, G.J, Wilson, K.S, Moeler, M.S, Meyer, A.S, Westh, P, Jensen, K, Krogh, K.B.R.M. | | 登録日 | 2021-03-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structural and functional characterization of a multi-domain GH92 alpha-1,2-mannosidase from Neobacillus novalis.
Acta Crystallogr D Struct Biol, 79, 2023
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8QAK
 | | Dispersin from Terribacillus saccharophilus DispTs3 | | 分子名称: | ACETATE ION, Glycoside hydrolase family 20 catalytic domain-containing protein | | 著者 | Males, A, Moroz, O.V, Blagova, E, Munch, A, Hansen, G.H, Johansen, A.H, Ostergaard, L.H, Segura, D.R, Eddenden, A, Due, A.V, Gudmand, M, Salomon, J, Sorensen, S.R, Cairo, J.L.F, Pache, R.A, Vejborg, R.M, Davies, G.J, Wilson, K.S. | | 登録日 | 2023-08-22 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Expansion of the diversity of dispersin scaffolds.
Acta Crystallogr D Struct Biol, 81, 2025
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8QB6
 | | Dispersin from Terribacillus saccharophilus DispTs2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE, Dispersin | | 著者 | Males, A, Moroz, O.V, Blagova, E, Munch, A, Hansen, G.H, Johansen, A.H, Ostergaard, L.H, Segura, D.R, Eddenden, A, Due, A.V, Gudmand, M, Salomon, J, Sorensen, S.R, Cairo, J.L.F, Pache, R.A, Vejborg, R.M, Davies, G.J, Wilson, K.S. | | 登録日 | 2023-08-24 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Expansion of the diversity of dispersin scaffolds.
Acta Crystallogr D Struct Biol, 81, 2025
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8QCE
 | | Dispersin from Lactiplantibacillus paraplantarum DispLp | | 分子名称: | 1,2-ETHANEDIOL, 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Males, A, Moroz, O.V, Blagova, E, Munch, A, Hansen, G.H, Johansen, A.H, Ostergaard, L.H, Segura, D.R, Eddenden, A, Due, A.V, Gudmand, M, Salomon, J, Sorensen, S.R, Cairo, J.L.F, Pache, R.A, Vejborg, R.M, Davies, G.J, Wilson, K.S. | | 登録日 | 2023-08-25 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Expansion of the diversity of dispersin scaffolds.
Acta Crystallogr D Struct Biol, 81, 2025
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2YAY
 | | The Crystal Structure of Leishmania major dUTPase in complex with substrate analogue dUpNpp | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DUTPASE | | 著者 | Hemsworth, G.R, Moroz, O.V, Fogg, M.J, Scott, B, Bosch-Navarrete, C, Gonzalez-Pacanowska, D, Wilson, K.S. | | 登録日 | 2011-02-25 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
J.Biol.Chem., 286, 2011
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5ADV
 | | The Periplasmic Binding Protein CeuE of Campylobacter jejuni preferentially binds the iron(III) complex of the Linear Dimer Component of Enterobactin | | 分子名称: | 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, 2S-2-[(2,3-DIHYDROXYPHENYL)CARBONYLAMINO]-3-[(2S)-2-[(2,3-DIHYDROXYPHENYL)CARBONYLAMINO]-3-HYDROXY-PROPANOYL]OXY-PROPANOIC ACID, DIMETHYL SULFOXIDE, ... | | 著者 | Raines, D.J, Moroz, O.V, Turkenburg, J.P, Wilson, K.S, Duhme-Klair, A.K. | | 登録日 | 2015-08-24 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Bacteria in an Intense Competition for Iron: Key Component of the Campylobacter Jejuni Iron Uptake System Scavenges Enterobactin Hydrolysis Product.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2C20
 | | CRYSTAL STRUCTURE OF UDP-GLUCOSE 4-EPIMERASE | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GLUCOSE 4-EPIMERASE, ZINC ION | | 著者 | Lebedev, A.A, Moroz, O.V, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S. | | 登録日 | 2005-09-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of Udp-Glucose 4-Epimerase from Bacillus Anthracis at 2.7A Resolution
To be Published
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5A1J
 | | Periplasmic Binding Protein CeuE in complex with ferric 4-LICAM | | 分子名称: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-butane-1,4-diylbis(2,3-dihydroxybenzamide) | | 著者 | Raines, D.J, Moroz, O.V, Wilson, K.S, Duhme-Klair, A.K. | | 登録日 | 2015-04-30 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Interactions of a Periplasmic Binding Protein with a Tetradentate Siderophore Mimic.
Angew.Chem.Int.Ed.Engl., 52, 2013
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5A5D
 | | A complex of the synthetic siderophore analogue Fe(III)-5-LICAM with the CeuE periplasmic protein from Campylobacter jejuni | | 分子名称: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-pentane-1,5-diylbis(2,3-dihydroxybenzamide) | | 著者 | Blagova, E, Hughes, A, Moroz, O.V, Raines, D.J, Wilde, E.J, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2015-06-17 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
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5AD1
 | | A complex of the synthetic siderophore analogue Fe(III)-8-LICAM with the CeuE periplasmic protein from Campylobacter jejuni | | 分子名称: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-OCTANE-1,8-DIYLBIS(2,3-DIHYDROXYBENZAMIDE) | | 著者 | Blagova, E, Hughes, A, Moroz, O.V, Raines, D.J, Wilde, E.J, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2015-08-19 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
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5ADW
 | | The Periplasmic Binding Protein CeuE of Campylobacter jejuni preferentially binds the iron(III) complex of the Linear Dimer Component of Enterobactin | | 分子名称: | 2S-2-[(2,3-DIHYDROXYPHENYL)CARBONYLAMINO]-3-[(2S)-2-[(2,3-DIHYDROXYPHENYL)CARBONYLAMINO]-3-HYDROXY-PROPANOYL]OXY-PROPANOIC ACID, DIMETHYL SULFOXIDE, ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, ... | | 著者 | Raines, D.J, Moroz, O.V, Turkenburg, J.P, Wilson, K.S, Duhme-Klair, A.K. | | 登録日 | 2015-08-24 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Bacteria in an Intense Competition for Iron: Key Component of the Campylobacter Jejuni Iron Uptake System Scavenges Enterobactin Hydrolysis Product.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5A5V
 | | A complex of the synthetic siderophore analogue Fe(III)-6-LICAM with the CeuE periplasmic protein from Campylobacter jejuni | | 分子名称: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-hexane-1,4-diylbis(2,3-dihydroxybenzamide) | | 著者 | Blagova, E, Hughes, A, Moroz, O.V, Raines, D.J, Wilde, E.J, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2015-06-22 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
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5AP9
 | | Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Skjold-Joergensen, J, Vind, J, Moroz, O.V, Blagova, E.V, Bhatia, V.K, Svendsen, A, Wilson, K.S, Bjerrum, M.J. | | 登録日 | 2015-09-15 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function.
Biochim. Biophys. Acta, 1865, 2017
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9EP6
 | | Alpha-Galactosaminidase family GH114 from Fusarium solani | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, alpha-galactosidase | | 著者 | Roth, C, Moroz, O.V, Miranda, S.A.D, Jahn, L, Blagova, E, Lebedev, A.A, Segura, D.R, Stringer, M.A, Friis, E.P, Davies, G.J, Wilson, K.S. | | 登録日 | 2024-03-17 | | 公開日 | 2025-04-23 | | 最終更新日 | 2025-05-14 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Structures of alpha-galactosaminidases from the CAZy GH114 family and homologs defining a new GH191 family of glycosidases.
Acta Crystallogr D Struct Biol, 81, 2025
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2C8J
 | | CRYSTAL STRUCTURE OF ferrochelatase HemH-1 from Bacillus anthracis, str. Ames | | 分子名称: | FERROCHELATASE 1 | | 著者 | Muller, A, Lebedev, A.A, Moroz, O.V, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S. | | 登録日 | 2005-12-05 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Ferrochelatase Hemh-1 from Bacillus Anthracis, Str. Ames
To be Published
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9FZ0
 | | Crystal structure of SusG from Bacteroides thetaiotaomicron covalently bound to alpha-1,6 branched pseudo-trisaccharide activity-based probe | | 分子名称: | (1~{R},2~{R},3~{S},4~{R},5~{R},6~{S})-5-(hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2,3,4-triol, (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, ACETATE ION, ... | | 著者 | Pickles, I.B, Moroz, O, Davies, G. | | 登録日 | 2024-07-04 | | 公開日 | 2024-12-11 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Precision Activity-Based alpha-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes.
Angew.Chem.Int.Ed.Engl., 64, 2025
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9FZ3
 | | Crystal structure of K38 amylase from Bacillus sp. strain KSM-K38 covalently bound to alpha-1,6 branched pseudo-trisaccharide activity-based probe | | 分子名称: | (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, ACETATE ION, Amylase, ... | | 著者 | Pickles, I.B, Moroz, O, Davies, G. | | 登録日 | 2024-07-04 | | 公開日 | 2024-12-11 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Precision Activity-Based alpha-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes.
Angew.Chem.Int.Ed.Engl., 64, 2025
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9FZ2
 | | Crystal structure of Amylase 5 (Amy5) from Ruminococcus bromii covalently bound to alpha-1,6 branched pseudo-trisaccharide activity-based probe | | 分子名称: | (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, 8-azanyloctan-1-ol, Alpha-amylase, ... | | 著者 | Pickles, I.B, Moroz, O, Davies, G. | | 登録日 | 2024-07-04 | | 公開日 | 2024-12-11 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Precision Activity-Based alpha-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes.
Angew.Chem.Int.Ed.Engl., 64, 2025
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9FYZ
 | | Crystal structure of SusA amylase from Bacteroides thetaiotaomicron covalently bound to alpha-1,6 branched pseudo-trisaccharide activity-based probe | | 分子名称: | (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, CALCIUM ION, IMIDAZOLE, ... | | 著者 | Pickles, I.B, Moroz, O, Davies, G. | | 登録日 | 2024-07-04 | | 公開日 | 2024-12-11 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Precision Activity-Based alpha-Amylase Probes for Dissection and Annotation of Linear and Branched-Chain Starch-Degrading Enzymes.
Angew.Chem.Int.Ed.Engl., 64, 2025
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2D30
 | | Crystal Structure of Cytidine Deaminase Cdd-2 (BA4525) from Bacillus Anthracis at 2.40A Resolution | | 分子名称: | ZINC ION, cytidine deaminase | | 著者 | Levdikov, V.M, Blagova, E.V, Fogg, M.J, Brannigan, J.A, Moroz, O.V, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE) | | 登録日 | 2005-09-21 | | 公開日 | 2006-09-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of Cytidine Deaminase Cdd-2 (BA4525) from Bacillus Anthracis at 2.40A Resolution
To be Published
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