9F5H
Crystal structure of MGAT5 bump-and-hole mutant in complex with UDP and M592
Summary for 9F5H
Entry DOI | 10.2210/pdb9f5h/pdb |
Descriptor | Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, URIDINE-5'-DIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | bump and hole, bioorthogonal tag, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 119420.74 |
Authors | Liu, Y.,Bineva-Todd, G.,Meek, R.,Mazo, L.,Piniello, B.,Moroz, O.V.,Begum, N.,Roustan, C.,Tomita, S.,Kjaer, S.,Rovira, C.,Davies, G.J.,Schumann, B. (deposition date: 2024-04-28, release date: 2024-10-02) |
Primary citation | Liu, Y.,Bineva-Todd, G.,Meek, R.W.,Mazo, L.,Piniello, B.,Moroz, O.,Burnap, S.A.,Begum, N.,Ohara, A.,Roustan, C.,Tomita, S.,Kjaer, S.,Polizzi, K.,Struwe, W.B.,Rovira, C.,Davies, G.J.,Schumann, B. A Bioorthogonal Precision Tool for Human N -Acetylglucosaminyltransferase V. J.Am.Chem.Soc., 2024 Cited by PubMed: 39287665DOI: 10.1021/jacs.4c05955 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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