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PDB: 64 件
6GMN
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BU of 6gmn by Molmil
pVHL:EloB:EloC in complex with methyl 4H-furo[3,2-b]pyrrole-5-carboxylate
分子名称: ACETATE ION, Elongin-B, Elongin-C, ...
著者Van Molle, I, Lucas, X, Ciulli, A.
登録日2018-05-27
公開日2018-08-08
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
J. Med. Chem., 61, 2018
6GMX
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BU of 6gmx by Molmil
pVHL:EloB:EloC in complex with 6-chlorothiochroman-4-one
分子名称: 6-chloranyl-2,3-dihydrothiochromen-4-one, ACETATE ION, Elongin-B, ...
著者Van Molle, I, Lucas, X, Ciulli, A.
登録日2018-05-28
公開日2018-08-08
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (2.533 Å)
主引用文献Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
J. Med. Chem., 61, 2018
5G1K
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BU of 5g1k by Molmil
A triple mutant of DsbG engineered for denitrosylation
分子名称: SULFATE ION, THIOL DISULFIDE INTERCHANGE PROTEIN DSBG
著者Tamu Dufe, V, Van Molle, I, Lafaye, C, Wahni, K, Boudier, A, Leroy, P, Collet, J.F, Messens, J.
登録日2016-03-28
公開日2016-05-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Sulfur Denitrosylation by an Engineered Trx-Like Dsbg Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.
J.Biol.Chem., 291, 2016
6GMR
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BU of 6gmr by Molmil
pVHL:EloB:EloC in complex with (4-(1H-pyrrol-1-yl)phenyl)methanol
分子名称: (4-pyrrol-1-ylphenyl)methanol, Elongin-B, Elongin-C, ...
著者Van Molle, I, Lucas, X, Ciulli, A.
登録日2018-05-28
公開日2018-08-08
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
J. Med. Chem., 61, 2018
5G1L
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BU of 5g1l by Molmil
A double mutant of DsbG engineered for denitrosylation
分子名称: SULFATE ION, THIOL DISULFIDE INTERCHANGE PROTEIN DSBG
著者Tamu Dufe, V, Van Molle, I, Lafaye, C, Wahni, K, Boudier, A, Leroy, P, Collet, J.F, Messens, J.
登録日2016-03-28
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Sulfur Denitrosylation by an Engineered Trx-Like Dsbg Enzyme Identifies Nucleophilic Cysteine Hydrogen Bonds as Key Functional Determinant.
J.Biol.Chem., 291, 2016
4BKT
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BU of 4bkt by Molmil
von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide
分子名称: (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ARGININE, GLUTAMIC ACID, ...
著者Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A.
登録日2013-04-29
公開日2013-11-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?
Acs Med.Chem.Lett., 5, 2014
4BKS
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BU of 4bks by Molmil
von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide
分子名称: (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ...
著者Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A.
登録日2013-04-29
公開日2013-11-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?
Acs Med.Chem.Lett., 5, 2014
6EP6
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BU of 6ep6 by Molmil
ARABIDOPSIS THALIANA GSTU23, reduced
分子名称: GLYCEROL, Glutathione S-transferase U23, MAGNESIUM ION
著者Tossounian, M.A, Van Molle, I, Wahni, K, Jacques, S, Vertommen, D, Gevaert, K, Van Breusegem, F, Young, D, Rosado, L, Messens, J.
登録日2017-10-10
公開日2018-04-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.592 Å)
主引用文献Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Biochim. Biophys. Acta, 1862, 2018
6EP7
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BU of 6ep7 by Molmil
ARABIDOPSIS THALIANA GSTU23, GSH bound
分子名称: GLUTATHIONE, GLYCEROL, Glutathione S-transferase U23, ...
著者Tossounian, M.A, Van Molle, I, Wahni, K, Jacques, S, Vertommen, D, Gevaert, K, Van Breusegem, F, Young, D, Rosado, L, Messens, J.
登録日2017-10-11
公開日2018-04-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.947 Å)
主引用文献Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Biochim. Biophys. Acta, 1862, 2018
3HLR
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BU of 3hlr by Molmil
Donor strand complemented FaeG of F4ad fimbriae
分子名称: K88 fimbrial protein AD
著者Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H.
登録日2009-05-28
公開日2009-10-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
6F01
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BU of 6f01 by Molmil
ARABIDOPSIS THALIANA GSTF9, GSO3 AND GSOH BOUND
分子名称: BROMIDE ION, GLUTATHIONE SULFONIC ACID, GLYCEROL, ...
著者Tossounian, M.A, Wahni, K, Van Molle, I, Vertommen, D, Rosado, L, Messens, J.
登録日2017-11-17
公開日2018-08-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility.
Protein Sci., 28, 2019
4D7L
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BU of 4d7l by Molmil
Methionine sulfoxide reductase A of Corynebacterium diphtheriae
分子名称: CACODYLATE ION, PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA, SULFATE ION, ...
著者Van Molle, I, Tossounian, M.A, Pedre, B, Wahni, K, Vertommen, D, Messens, J.
登録日2014-11-25
公開日2015-03-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Corynebacterium Diphtheriae Methionine Sulfoxide Reductase a Exploits a Unique Mycothiol Redox Relay Mechanism.
J.Biol.Chem., 290, 2015
1ZPL
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BU of 1zpl by Molmil
E. coli F17a-G lectin domain complex with GlcNAc(beta1-O)Me
分子名称: F17a-G, methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside
著者Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2005-05-17
公開日2006-05-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
2J6R
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BU of 2j6r by Molmil
FaeG from F4ac ETEC strain GIS26, produced in tobacco plant chloroplast
分子名称: K88 FIMBRIAL PROTEIN, PHOSPHATE ION
著者Van Molle, I, Joensuu, J.J, Buts, L, Panjikar, S, Kotiaho, M, Bouckaert, J, Wyns, L, Niklander-Teeri, V, De Greve, H.
登録日2006-10-03
公開日2007-04-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Chloroplasts Assemble the Major Subunit Faeg of Escherichia Coli F4 (K88) Fimbriae Into Strand-Swapped Dimers
J.Mol.Biol., 368, 2007
3F65
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BU of 3f65 by Molmil
The F4 fimbrial chaperone FaeE does not self-cap its interactive surfaces
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Chaperone protein faeE, PHOSPHATE ION
著者Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J.
登録日2008-11-05
公開日2009-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
Acta Crystallogr.,Sect.D, 65, 2009
3GEW
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BU of 3gew by Molmil
FaeE-FaeG chaperone-major pilin complex of F4 ad fimbriae
分子名称: Chaperone protein faeE, GLYCEROL, K88 fimbrial protein AD, ...
著者Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H.
登録日2009-02-26
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
5O84
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BU of 5o84 by Molmil
Glutathione S-transferase Tau 23 (partially oxidized)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FORMIC ACID, ...
著者Young, D.R, Van Molle, I, Tossounian, M, Messens, J.
登録日2017-06-12
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage.
Biochim. Biophys. Acta, 1862, 2018
1ZK5
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BU of 1zk5 by Molmil
Escherichia coli F17fG lectin domain complex with N-acetylglucosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G adhesin subunit
著者Buts, L, Wellens, A, Van Molle, I, De Genst, E, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2005-05-02
公開日2006-05-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
3GEA
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BU of 3gea by Molmil
Donor strand complemented FaeG monomer of F4 variant ad
分子名称: GLYCEROL, K88 fimbrial protein AD, SULFATE ION
著者Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H.
登録日2009-02-25
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
3GGH
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BU of 3ggh by Molmil
Donor strand complemented FaeG of F4ad fimbriae
分子名称: K88 fimbrial protein AD, SULFATE ION
著者Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H.
登録日2009-02-28
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.639 Å)
主引用文献Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
6ESX
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BU of 6esx by Molmil
Caulobacter crescentus Trx1
分子名称: Thioredoxin 1
著者Van Molle, I, Wahni, K, Goemans, C.V, Beaufay, F, Collet, J.F, Messens, J.
登録日2017-10-24
公開日2018-01-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献An essential thioredoxin is involved in the control of the cell cycle in the bacterium
J. Biol. Chem., 293, 2018
3GFU
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BU of 3gfu by Molmil
FaeE-FaeG chaperone-major pilin complex of F4 ac 5/95 fimbriae
分子名称: Chaperone protein faeE, FaeG, SULFATE ION
著者Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H.
登録日2009-02-27
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
4QF2
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BU of 4qf2 by Molmil
Crystal structure of human BAZ2A PHD zinc finger in the free form
分子名称: Bromodomain adjacent to zinc finger domain protein 2A, GLYCEROL, PHOSPHATE ION, ...
著者Tallant, C, Overvoorde, L, Van Molle, I, Chirgadze, D.Y, Ciulli, A.
登録日2014-05-19
公開日2014-07-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
3ZTC
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BU of 3ztc by Molmil
pVHL54-213-EloB-EloC complex _ (2S,4R)-N-((1,1'-biphenyl)-4-ylmethyl)- 4-hydroxy-1-(2-(3-methylisoxazol-5-yl)acetyl)pyrrolidine-2- carboxamide
分子名称: (4R)-N-(BIPHENYL-4-YLMETHYL)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-L-PROLINAMIDE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ...
著者Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A.
登録日2011-07-06
公開日2012-07-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface.
Chem.Biol., 19, 2012
3ZRC
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BU of 3zrc by Molmil
pVHL54-213-EloB-EloC complex (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE bound
分子名称: (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ...
著者Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A.
登録日2011-06-15
公開日2012-03-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Targeting the Von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules to Disrupt the Vhl/Hif-1Alpha Interaction
J.Am.Chem.Soc., 134, 2012

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