2KRE
 
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2FK4
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6KX0
 | | Crystal structure of SN-101 mAb non-liganded form | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain | | 著者 | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | | 登録日 | 2019-09-09 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | | 主引用文献 | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Chem Sci, 11, 2020
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6KX1
 | | Crystal structure of SN-101 mAb in complex with MUC1 glycopeptide | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, ... | | 著者 | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | | 登録日 | 2019-09-09 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.773 Å) | | 主引用文献 | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Chem Sci, 11, 2020
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6KNE
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6KND
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2E6U
 | | Crystal structure of hypothetical protein PH1109 from Pyrococcus horikoshii | | 分子名称: | CALCIUM ION, CHLORIDE ION, COENZYME A, ... | | 著者 | Kitago, Y, Min, Y, Watanabe, N, Tanaka, I. | | 登録日 | 2007-01-03 | | 公開日 | 2007-01-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure determination of a novel protein by sulfur SAD using chromium radiation in combination with a new crystal-mounting method
ACTA CRYSTALLOGR.,SECT.D, 61, 2005
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4TKC
 | | Japanese Marasmius oreades lectin complexed with mannose | | 分子名称: | GLYCEROL, Mannose recognizing lectin, alpha-D-mannopyranose, ... | | 著者 | Noma, Y, Shimokawa, M, Maeganeku, C, Motoshima, H, Watanabe, K, Minami, Y, Yagi, F. | | 登録日 | 2014-05-26 | | 公開日 | 2015-06-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Structure of Japanese Marasmius oreades lectin complexed with mannose.
To Be Published
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5ZV2
 | | FGFR-1 in complex with ligand lenvatinib | | 分子名称: | 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide, Fibroblast growth factor receptor 1 | | 著者 | Matsuki, M, Hoshi, T, Yamamoto, Y, Ikemori-Kawada, M, Minoshima, Y, Funahashi, Y, Matsui, J. | | 登録日 | 2018-05-09 | | 公開日 | 2018-07-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma models.
Cancer Med, 7, 2018
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7BOT
 | | Human SIRT2 in complex with myristoyl thiourea inhibitor, No.23 | | 分子名称: | N-dodecylmethanethioamide, NAD-dependent protein deacetylase sirtuin-2, ZINC ION, ... | | 著者 | Kudo, N, Olsen, C.A, Minoru, Y. | | 登録日 | 2020-03-19 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of alpha-tubulin acetylation and inhibition of breast cancer cell migration.
Rsc Chem Biol, 2, 2021
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7BOS
 | | Human SIRT2 in complex with myristoyl thiourea inhibitor, No.13 | | 分子名称: | Myristoyl thiourea inhibitor, No.13, N-dodecylmethanethioamide, ... | | 著者 | Kudo, N, Olsen, C.A, Minoru, Y. | | 登録日 | 2020-03-19 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of alpha-tubulin acetylation and inhibition of breast cancer cell migration.
Rsc Chem Biol, 2, 2021
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8I4O
 | | Design of a split green fluorescent protein for sensing and tracking an beta-amyloid | | 分子名称: | Beta-amyloid, Split Green flourescent protein | | 著者 | Taegeun, Y, Jinsu, L, Jungmin, Y, Jungmin, C, Wondo, H, Song, J.J, Haksung, K. | | 登録日 | 2023-01-20 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Engineering of a Fluorescent Protein for a Sensing of an Intrinsically Disordered Protein through Transition in the Chromophore State.
Jacs Au, 3, 2023
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4PDT
 | | Japanese Marasmius oreades lectin | | 分子名称: | Mannose recognizing lectin, SULFATE ION | | 著者 | Noma, Y, Shimokawa, M, Maeganeku, C, Motoshima, H, Watanabe, K, Minami, Y, Yagi, F. | | 登録日 | 2014-04-22 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The structure of Japanese Marasmius oreades lectin at 1.40 Angstroms resolution.
To Be Published
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2KPK
 | | MAGI-1 PDZ1 | | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | | 著者 | Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A. | | 登録日 | 2009-10-16 | | 公開日 | 2010-10-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
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2KPL
 | | MAGI-1 PDZ1 / E6CT | | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Protein E6 | | 著者 | Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A. | | 登録日 | 2009-10-16 | | 公開日 | 2010-10-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
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5F4N
 | | Multi-parameter lead optimization to give an oral CHK1 inhibitor clinical candidate: (R)-5-((4-((morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Serine/threonine-protein kinase Chk1, ... | | 著者 | Collins, I, Garrett, M.D, van Montfort, R, Osborne, J.D, Matthews, T.P, McHardy, T, Proisy, N, Cheung, K.J, Lainchbury, M, Brown, N, Walton, M.I, Eve, P.D, Boxall, K.J, Hayes, A, Henley, A.T, Valenti, M.R, De Haven Brandon, A.K, Box, G, Westwood, I.M, Jamin, Y, Robinson, S.P, Leonard, P, Reader, J.C, Aherne, G.W, Raynaud, F.I, Eccles, S.A. | | 登録日 | 2015-12-03 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737).
J.Med.Chem., 59, 2016
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2ZV2
 | | Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609 | | 分子名称: | 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, Calcium/calmodulin-dependent protein kinase kinase 2 | | 著者 | Yoshikawa, S, Kukimoto-niino, M, Shirouzu, M, Suzuki, A, Lee, S, Minokoshi, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-10-31 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609
J.Biol.Chem., 286, 2011
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2YZQ
 | | Crystal structure of uncharacterized conserved protein from Pyrococcus horikoshii | | 分子名称: | Putative uncharacterized protein PH1780, S-ADENOSYLMETHIONINE | | 著者 | Kanagawa, M, Minami, Y, Watanabe, N, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-05-06 | | 公開日 | 2007-11-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Crystal structure of uncharacterized conserved protein from Pyrococcus horikoshii
To be Published
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2D2A
 | | Crystal Structure of Escherichia coli SufA Involved in Biosynthesis of Iron-sulfur Clusters | | 分子名称: | SufA protein | | 著者 | Wada, K, Hasegawa, Y, Gong, Z, Minami, Y, Fukuyama, K, Takahashi, Y. | | 登録日 | 2005-09-05 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of Escherichia coli SufA involved in biosynthesis of iron-sulfur clusters: Implications for a functional dimer
Febs Lett., 579, 2005
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2D3W
 | | Crystal Structure of Escherichia coli SufC, an ATPase compenent of the SUF iron-sulfur cluster assembly machinery | | 分子名称: | Probable ATP-dependent transporter sufC | | 著者 | Kitaoka, S, Wada, K, Hasegawa, Y, Minami, Y, Takahashi, Y, Fukuyama, K. | | 登録日 | 2005-10-03 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of Escherichia coli SufC, an ABC-type ATPase component of the SUF iron-sulfur cluster assembly machinery
Febs Lett., 580, 2006
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1IO5
 | | HYDROGEN AND HYDRATION OF HEN EGG-WHITE LYSOZYME DETERMINED BY NEUTRON DIFFRACTION | | 分子名称: | LYSOZYME C | | 著者 | Niimura, N, Minezaki, Y, Nonaka, T, Castagna, J.C, Cipriani, F, Hoeghoej, P, Lehmann, M.S, Wilkinson, C. | | 登録日 | 2001-01-14 | | 公開日 | 2001-02-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | NEUTRON DIFFRACTION (2 Å) | | 主引用文献 | Neutron Laue diffractometry with an imaging plate provides an effective data collection regime for neutron protein crystallography.
Nat.Struct.Biol., 4, 1997
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2EIX
 | | The Structure of Physarum polycephalum cytochrome b5 reductase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, IODIDE ION, ... | | 著者 | Kim, S.W, Suga, M, Ogasahara, K, Ikegami, T, Minami, Y, Yubisui, T, Tsukihara, T. | | 登録日 | 2007-03-14 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structure of Physarum polycephalum cytochrome b5 reductase at 1.56 A resolution.
Acta Crystallogr.,Sect.F, 63, 2007
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3ZJB
 | | The structure of the TRAF domain of human TRAF4 | | 分子名称: | CHLORIDE ION, TNF RECEPTOR-ASSOCIATED FACTOR 4 | | 著者 | McEwen, A.G, Poussin-Courmontagne, P, Rousseau, A, Rogna, D, Nomine, Y, Rio, M.-C, Tomasetto, C, Alpy, F. | | 登録日 | 2013-01-17 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Traf4 is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration.
Plos Biol., 11, 2013
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2B02
 | | Crystal Structure of ARNT PAS-B Domain | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator | | 著者 | Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G. | | 登録日 | 2005-09-12 | | 公開日 | 2006-10-24 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain
To be Published
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7C4M
 | | Ancestral L-amino acid oxidase (AncLAAO-N5) L-Trp binding form | | 分子名称: | Ancestral L-amino acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, TRYPTOPHAN | | 著者 | Nakano, S, Minamino, Y, Karasuda, H, Ito, S. | | 登録日 | 2020-05-18 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids
Commun Chem, 3, 2020
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