5C98
 
 | | 1.45A resolution structure of SRPN18 from Anopheles gambiae | | 分子名称: | AGAP007691-PB | | 著者 | Lovell, S, Battaile, K.P, Gulley, M, Zhang, X, Meekins, D.A, Gao, F.P, Michel, K. | | 登録日 | 2015-06-26 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | 1.45 angstrom resolution structure of SRPN18 from the malaria vector Anopheles gambiae.
Acta Crystallogr F Struct Biol Commun, 72, 2016
|
|
4RSQ
 | | 2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-11-10 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
|
|
4ROA
 | | 1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
|
|
4RO9
 | | 2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae | | 分子名称: | GLYCEROL, Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae.
J.Biol.Chem., 290, 2015
|
|
4ROB
 | | 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | | 登録日 | 2014-10-28 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae
To be Published
|
|
3PZF
 | | 1.75A resolution structure of Serpin-2 from Anopheles gambiae | | 分子名称: | Serpin 2 | | 著者 | Lovell, S, Battaile, K.P, An, C, Michel, K. | | 登録日 | 2010-12-14 | | 公開日 | 2011-02-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoes.
Proteins, 79, 2011
|
|
4MRO
 | | Human GKRP bound to AMG-5980 and S6P | | 分子名称: | 2-(4-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | | 著者 | St Jean, D.J, Ashton, K.S, Bartberger, M.D, Chen, J, Chmait, S, Cupples, R, Galbreath, E, Helmering, J, Jordan, S.R, Liu, L, Kunz, K, Michelsen, K, Nishimura, N, Pennington, L.D, Poon, S.F, Sivits, G, Stec, M.M, Tamayo, N, Van, G, Yang, K, Norman, M.H, Fotsch, C, LLoyd, D.J, Hale, C. | | 登録日 | 2013-09-17 | | 公開日 | 2014-05-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
J.Med.Chem., 57, 2014
|
|
4MSU
 | | Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate | | 分子名称: | 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | | 著者 | Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J. | | 登録日 | 2013-09-18 | | 公開日 | 2014-03-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept.
J.Med.Chem., 57, 2014
|
|
5SX4
 | | Crystal Structure of panitumumab in complex with epidermal growth factor receptor domain 3. | | 分子名称: | 1,2-ETHANEDIOL, Epidermal growth factor receptor, GLYCEROL, ... | | 著者 | Sickmier, E.A, Kurzeja, R.J.M, Michelsen, K, Mukta, V, Yang, E, Tasker, A.S. | | 登録日 | 2016-08-09 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Panitumumab EGFR Complex Reveals a Binding Mechanism That Overcomes Cetuximab Induced Resistance.
Plos One, 11, 2016
|
|
