7T6D
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![BU of 7t6d by Molmil](/molmil-images/mine/7t6d) | CryoEM structure of the YejM/LapB complex | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Inner membrane protein YejM, ... | Authors: | Mi, W, Shu, S. | Deposit date: | 2021-12-13 | Release date: | 2022-08-17 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli. Nat Commun, 13, 2022
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8V24
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![BU of 8v24 by Molmil](/molmil-images/mine/8v24) | LapB cytoplasmic domain in complex with LpxC | Descriptor: | ACETATE ION, Lipopolysaccharide assembly protein B, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | Authors: | Mi, W, Shu, S. | Deposit date: | 2023-11-21 | Release date: | 2024-04-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Dual function of LapB (YciM) in regulating Escherichia coli lipopolysaccharide synthesis. Proc.Natl.Acad.Sci.USA, 121, 2024
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5TTP
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![BU of 5ttp by Molmil](/molmil-images/mine/5ttp) | |
5TV4
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![BU of 5tv4 by Molmil](/molmil-images/mine/5tv4) | 3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc | Descriptor: | 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ... | Authors: | Mi, W, Walz, T, Liao, M. | Deposit date: | 2016-11-08 | Release date: | 2017-09-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of MsbA-mediated lipopolysaccharide transport. Nature, 549, 2017
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5V7V
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![BU of 5v7v by Molmil](/molmil-images/mine/5v7v) | Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M. | Deposit date: | 2017-03-20 | Release date: | 2017-08-16 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature, 548, 2017
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6DBL
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![BU of 6dbl by Molmil](/molmil-images/mine/6dbl) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (5.001 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBR
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![BU of 6dbr by Molmil](/molmil-images/mine/6dbr) | Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS | Descriptor: | CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBQ
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![BU of 6dbq by Molmil](/molmil-images/mine/6dbq) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBW
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![BU of 6dbw by Molmil](/molmil-images/mine/6dbw) | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | Descriptor: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBT
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![BU of 6dbt by Molmil](/molmil-images/mine/6dbt) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBX
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![BU of 6dbx by Molmil](/molmil-images/mine/6dbx) | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | Descriptor: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBV
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![BU of 6dbv by Molmil](/molmil-images/mine/6dbv) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.291 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBI
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![BU of 6dbi by Molmil](/molmil-images/mine/6dbi) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | Descriptor: | CALCIUM ION, Forward strand of 12-RSS signal end, Forward strand of 23-RSS signal end, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBU
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![BU of 6dbu by Molmil](/molmil-images/mine/6dbu) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DBJ
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![BU of 6dbj by Molmil](/molmil-images/mine/6dbj) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | Descriptor: | CALCIUM ION, Forward stand of RSS signal end, Forward strand of coding flank, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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3MXZ
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![BU of 3mxz by Molmil](/molmil-images/mine/3mxz) | Crystal Structure of tubulin folding cofactor A from Arabidopsis thaliana | Descriptor: | NITRATE ION, Tubulin-specific chaperone A | Authors: | Lu, L, Nan, J, Mi, W, Su, X.D, Li, Y. | Deposit date: | 2010-05-08 | Release date: | 2010-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Crystal structure of tubulin folding cofactor A from Arabidopsis thaliana and its beta-tubulin binding characterization Febs Lett., 584, 2010
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3NR2
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![BU of 3nr2 by Molmil](/molmil-images/mine/3nr2) | Crystal structure of Caspase-6 zymogen | Descriptor: | Caspase-6 | Authors: | Su, X.-D, Wang, X.-J, Liu, X, Mi, W, Wang, K.-T. | Deposit date: | 2010-06-30 | Release date: | 2010-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation Embo Rep., 11, 2010
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6DBO
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![BU of 6dbo by Molmil](/molmil-images/mine/6dbo) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | Descriptor: | CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ... | Authors: | Wu, H, Liao, M, Ru, H, Mi, W. | Deposit date: | 2018-05-03 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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2PER
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![BU of 2per by Molmil](/molmil-images/mine/2per) | |
5V6P
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![BU of 5v6p by Molmil](/molmil-images/mine/5v6p) | CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1 | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1 | Authors: | Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M. | Deposit date: | 2017-03-17 | Release date: | 2017-08-16 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature, 548, 2017
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8DFM
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![BU of 8dfm by Molmil](/molmil-images/mine/8dfm) | Ectodomain of full-length wild-type KIT-SCF dimers | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | Authors: | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | Deposit date: | 2022-06-22 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFQ
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![BU of 8dfq by Molmil](/molmil-images/mine/8dfq) | Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | Authors: | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | Deposit date: | 2022-06-22 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFP
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![BU of 8dfp by Molmil](/molmil-images/mine/8dfp) | Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | Authors: | Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J. | Deposit date: | 2022-06-22 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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