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PDB: 11 results
6PW2
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BU of 6pw2 by Molmil
Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication
Descriptor: DNA (62-MER), DNA (62-MER) complementary DNA strand, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E, Malecka, K.A, Lieberman, P.M.
Deposit date:2019-07-22
Release date:2019-08-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
J.Virol., 93, 2019
3BY4
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BU of 3by4 by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
Authors:Messick, T.E, Marmorstein, R.
Deposit date:2008-01-15
Release date:2008-02-19
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
3C0R
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BU of 3c0r by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
Authors:Messick, T.E, Marmorstein, R.
Deposit date:2008-01-21
Release date:2008-02-19
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
6VH6
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BU of 6vh6 by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragment
Descriptor: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E, Lieberman, P.M.
Deposit date:2020-01-09
Release date:2020-05-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.
Molecules, 25, 2020
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
Descriptor: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
Deposit date:2002-01-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
5WMF
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BU of 5wmf by Molmil
Crystal structure of the Hexameric Ring of Epstein-Barr Virus Nuclear Antigen-1, EBNA1
Descriptor: Epstein-Barr nuclear antigen 1
Authors:Messick, T.E.
Deposit date:2017-07-28
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.
J. Virol., 91, 2017
6NPM
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BU of 6npm by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
Descriptor: 5-(phenylethynyl)pyridine-3-carboxylic acid, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E.
Deposit date:2019-01-17
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
6NPI
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BU of 6npi by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
Descriptor: ({2-[(4-bromo-5-methyl-1,2-oxazol-3-yl)amino]-2-oxoethyl}sulfanyl)acetic acid, 2-pyrrol-1-ylbenzoic acid, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E.
Deposit date:2019-01-17
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
6NPP
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BU of 6npp by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
Descriptor: 3-(phenylethynyl)-2-(1H-pyrrol-1-yl)benzoic acid, EBNA1, Epstein-Barr nuclear antigen 1
Authors:Messick, T.E.
Deposit date:2019-01-18
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
5T7X
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BU of 5t7x by Molmil
Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA
Descriptor: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1
Authors:Malecka, K.A, Messick, T.E, Lieberman, P.M.
Deposit date:2016-09-06
Release date:2017-07-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Oncotarget, 8, 2017
3LBX
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BU of 3lbx by Molmil
Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex
Descriptor: Spectrin alpha chain, erythrocyte, Spectrin beta chain
Authors:Ipsaro, J.J, Harper, S.L, Messick, T.E, Marmorstein, R, Mondragon, A, Speicher, D.W.
Deposit date:2010-01-08
Release date:2010-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.
Blood, 115, 2010

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