1DEF
 
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2DEF
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6SJZ
 | | HsNMT1 in complex with both MyrCoA and Acetylated-GNCFSKPR substrates | | 分子名称: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | | 著者 | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | 登録日 | 2019-08-14 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
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6QRM
 | | HsNMT1 in complex with both MyrCoA and GNCFSKRRAA substrates | | 分子名称: | Apoptosis-inducing factor 3, CHLORIDE ION, COENZYME A, ... | | 著者 | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | 登録日 | 2019-02-19 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
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6SK3
 | | C-terminal HsNMT1 deltaC3 truncation in complex with both MyrCoA and GNCFSKPR substrates | | 分子名称: | Apoptosis-inducing factor 3, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | 登録日 | 2019-08-14 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
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6SK2
 | | HsNMT1 in complex with both MyrCoA and Acetylated-GKSFSKPR peptide reveals N-terminal Lysine Myristoylation | | 分子名称: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | | 著者 | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | 登録日 | 2019-08-14 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.90000653 Å) | | 主引用文献 | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
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6SKJ
 | | DeltaC2 C-terminal truncation of HsNMT1 in complex with MyrCoA and GNCFSKPR substrates | | 分子名称: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | | 著者 | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
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6SK8
 | | DeltaC3 C-terminal truncation of HsNMT1 in complex with MyrCoA and GDCFSKPR substrates | | 分子名称: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | | 著者 | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | 登録日 | 2019-08-14 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
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5MTE
 | | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T in complex with actinonin - crystal form II | | 分子名称: | ACTINONIN, NICKEL (II) ION, Putative uncharacterized protein orf60T, ... | | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | | 登録日 | 2017-01-09 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts.
Biochim. Biophys. Acta, 1866, 2018
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5MTD
 | | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II | | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... | | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | | 登録日 | 2017-01-09 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation.
Sci Rep, 7, 2017
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5MTC
 | | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I | | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION | | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | | 登録日 | 2017-01-09 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation.
Sci Rep, 7, 2017
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4JE7
 | | Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin | | 分子名称: | ACTINONIN, Peptide deformylase 1A, chloroplastic/mitochondrial, ... | | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | | 登録日 | 2013-02-26 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
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4JE6
 | | Crystal structure of a human-like mitochondrial peptide deformylase | | 分子名称: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION | | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | | 登録日 | 2013-02-26 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
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4JE8
 | | Crystal structure of a human-like mitochondrial peptide deformylase in complex with Met-Ala-Ser | | 分子名称: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION, ... | | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | | 登録日 | 2013-02-26 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
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1ZXZ
 | | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-5000 MME as precipitant | | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION | | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | | 登録日 | 2005-06-09 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
J.Biol.Chem., 280, 2005
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1ZY0
 | | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-6000 | | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION | | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | | 登録日 | 2005-06-09 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
J.Biol.Chem., 280, 2005
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1ZY1
 | | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A) in complex with Met-Ala-Ser | | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION, ... | | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | | 登録日 | 2005-06-09 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms
J.Biol.Chem., 280, 2005
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3M6Q
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3M6P
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3M6O
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3M6R
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1LRY
 | | Crystal Structure of P. aeruginosa Peptide Deformylase Complexed with Antibiotic Actinonin | | 分子名称: | ACTINONIN, PEPTIDE deformylase, ZINC ION | | 著者 | Guilloteau, J.-P, Mathieu, M, Giglione, C, Blanc, V, Dupuy, A, Chevrier, M, Gil, P, Famechon, A, Meinnel, T, Mikol, V. | | 登録日 | 2002-05-16 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
J.Mol.Biol., 320, 2002
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7OWP
 | | HsNMT1 in complex with both MyrCoA and ACE-G-(L-ORN)SFSKPR | | 分子名称: | ACE-GLY-ORN-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWR
 | | HsNMT1 in complex with both MyrCoA and peptide GGKSFSKPR | | 分子名称: | GLY-GLY-LYS-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWQ
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