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1LRY

Crystal Structure of P. aeruginosa Peptide Deformylase Complexed with Antibiotic Actinonin

Summary for 1LRY
Entry DOI10.2210/pdb1lry/pdb
Related1LQW 1LQY 1LRU
DescriptorPEPTIDE deformylase, ZINC ION, ACTINONIN, ... (4 entities in total)
Functional Keywordsactinonin, inhibition, polypeptide deformylase, hydrolase
Biological sourcePseudomonas aeruginosa
Total number of polymer chains1
Total formula weight19710.87
Authors
Guilloteau, J.-P.,Mathieu, M.,Giglione, C.,Blanc, V.,Dupuy, A.,Chevrier, M.,Gil, P.,Famechon, A.,Meinnel, T.,Mikol, V. (deposition date: 2002-05-16, release date: 2002-07-24, Last modification date: 2024-02-14)
Primary citationGuilloteau, J.P.,Mathieu, M.,Giglione, C.,Blanc, V.,Dupuy, A.,Chevrier, M.,Gil, P.,Famechon, A.,Meinnel, T.,Mikol, V.
The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
J.Mol.Biol., 320:951-962, 2002
Cited by
PubMed: 12126617
DOI: 10.1016/S0022-2836(02)00549-1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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