6ZK7
 
 | | Crystal Structure of human PYROXD1/FAD complex | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | | Authors: | Meinhart, A, Asanovic, I, Martinez, J, Clausen, T. | | Deposit date: | 2020-06-30 | | Release date: | 2021-05-12 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol.Cell, 81, 2021
|
|
1GVN
 | | Crystal Structure of the Plasmid Maintenance System epsilon/zeta: Meachnism of toxin inactivation and toxin function | | Descriptor: | EPSILON, SULFATE ION, ZETA | | Authors: | Meinhart, A, Alonso, J.C, Straeter, N, Saenger, W. | | Deposit date: | 2002-02-19 | | Release date: | 2003-01-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal Structure of the Plasmid Maintenance System Epsilon /Zeta : Functional Mechanism of Toxin Zeta and Inactivation by Epsilon 2 Zeta 2 Complex Formation
Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1Q1H
 | |
7AA4
 | | Structure of ClpC1-NTD bound to a CymA analogue | | Descriptor: | Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue | | Authors: | Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. | | Deposit date: | 2020-09-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
|
|
6QDJ
 | | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin | | Descriptor: | 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Meinhart, A, Clausen, T, Arnese, R. | | Deposit date: | 2019-01-02 | | Release date: | 2019-10-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.884 Å) | | Cite: | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
|
|
6QDM
 | |
6QDL
 | |
6QDK
 | |
8B9O
 | |
8B9U
 | |
1SZA
 | |
1SZ9
 | |
3CLJ
 | | Structure of the RNA polymerase II CTD-interacting domain of Nrd1 | | Descriptor: | GLYCEROL, Protein NRD1, SULFATE ION | | Authors: | Vasiljeva, L, Kim, M, Mutschler, H, Buratowski, S, Meinhart, A. | | Deposit date: | 2008-03-19 | | Release date: | 2008-07-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 15, 2008
|
|
2L0I
 | | Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide | | Descriptor: | DNA-directed RNA polymerase, Regulator of Ty1 transposition protein 103 | | Authors: | Lunde, B.M, Reichow, S.L, Kim, M, Suh, H, Leeper, T.C, Yang, F, Mutschler, H, Buratowski, S, Meinhart, A, Varani, G. | | Deposit date: | 2010-07-06 | | Release date: | 2010-09-08 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
|
|
4OI0
 | | bound to ssRNA dinucleotide GC, ADP, AlF4-, and Mg2+(transition state, data set I) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | Deposit date: | 2014-01-18 | | Release date: | 2014-05-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
|
|
4OI4
 | | Protein complex of Clp1 bound to ATP and Mg2+ with Pcf11deltaN454deltaC563 of S. cerevisiae | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | Deposit date: | 2014-01-18 | | Release date: | 2014-05-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
|
|
4OHZ
 | | bound to ssRNA tetranucleotide GAAA, ADP, and Mg2+ | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | Deposit date: | 2014-01-18 | | Release date: | 2014-05-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
|
|
4XW3
 | |
4OHW
 | | C. Elegans Clp1 bound to ATP, and Mn2+(ATP-bound state) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, NONAETHYLENE GLYCOL, ... | | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | Deposit date: | 2014-01-18 | | Release date: | 2014-05-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
|
|
4OHX
 | | C. Elegans Clp1 bound to ADP and Mg2+ (RNA released state) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... | | Authors: | Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. | | Deposit date: | 2014-01-18 | | Release date: | 2014-05-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1.
Mol.Cell, 54, 2014
|
|
6TV6
 | | Octameric McsB from Bacillus subtilis. | | Descriptor: | MAGNESIUM ION, Protein-arginine kinase | | Authors: | Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T. | | Deposit date: | 2020-01-09 | | Release date: | 2021-07-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.
Elife, 10, 2021
|
|
4FGE
 | | Structure of the effector protein Tse1 from Pseudomonas aeruginosa | | Descriptor: | CHLORIDE ION, GLYCEROL, THIOCYANATE ION, ... | | Authors: | Benz, J, Sendlmeier, C, Barends, T.R.M, Meinhart, A. | | Deposit date: | 2012-06-04 | | Release date: | 2012-06-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Insights into the Effector - Immunity System Tse1/Tsi1 from Pseudomonas aeruginosa.
Plos One, 7, 2012
|
|
8BRH
 | | Co-crystal structure of She4 with Myo4 peptide | | Descriptor: | KLLA0E16699p, Myo4 peptide (LYS-PHE-ILE-VAL-SER-HIS-TYR) | | Authors: | Arnese, R, Gudino, R, Meinhart, A, Clausen, T. | | Deposit date: | 2022-11-23 | | Release date: | 2024-06-05 | | Last modified: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
|
|
8BRG
 | | Crystal structure of She4 | | Descriptor: | KLLA0E16699p | | Authors: | Gudino, R, Arnese, R, Meinhart, A, Clausen, T. | | Deposit date: | 2022-11-23 | | Release date: | 2024-06-05 | | Last modified: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
|
|
4FHP
 | | Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - CaUTP bound | | Descriptor: | CALCIUM ION, GLYCEROL, Poly(A) RNA polymerase protein cid1, ... | | Authors: | Lunde, B.M, Magler, I, Meinhart, A. | | Deposit date: | 2012-06-06 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.
Nucleic Acids Res., 40, 2012
|
|
