8PHV
 
 | | Structure of Human selenomethionylated Cdc123 bound to domain 3 of eIF2 gamma | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123 homolog, Eukaryotic translation initiation factor 2 subunit 3 | | 著者 | Schmitt, E, Mechulam, Y, Cardenal Peralta, C, Fagart, J, Seufert, W. | | 登録日 | 2023-06-20 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Binding of human Cdc123 to eIF2 gamma.
J.Struct.Biol., 215, 2023
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8PHD
 | | Structure of Human Cdc123 bound to domain 3 of eIF2 gamma and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein 123 homolog, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Schmitt, E, Mechulam, Y, Cardenal Peralta, C, Fagart, J, Seufert, W. | | 登録日 | 2023-06-19 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Binding of human Cdc123 to eIF2 gamma.
J.Struct.Biol., 215, 2023
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6Y4B
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6Y3G
 | | Crystal structure of phenylalanine tRNA from Escherichia coli | | 分子名称: | CALCIUM ION, GLYCEROL, GUANIDINE, ... | | 著者 | Bourgeois, G, Mechulam, Y, Schmitt, E. | | 登録日 | 2020-02-18 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates.
Rna, 26, 2020
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6Q6R
 | | Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex | | 分子名称: | ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex | | 著者 | Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T. | | 登録日 | 2018-12-11 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
J.Struct.Biol., 209, 2020
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6QJO
 | | DNA containing both right- and left-handed parallel-stranded G-quadruplexes | | 分子名称: | DNA (28-MER), POTASSIUM ION | | 著者 | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T. | | 登録日 | 2019-01-24 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
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1FMT
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5MLQ
 | | Structure of CDPS from Nocardia brasiliensis | | 分子名称: | CDPS, CITRIC ACID | | 著者 | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | | 登録日 | 2016-12-07 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
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5OCD
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5MLP
 | | Structure of CDPS from Rickettsiella grylli | | 分子名称: | Uncharacterized protein | | 著者 | Bourgeois, G, Seguin, J, Moutiez, M, Babin, M, Belin, P, Mechulam, Y, Gondry, M, Schmitt, E. | | 登録日 | 2016-12-07 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural basis for partition of the cyclodipeptide synthases into two subfamilies.
J.Struct.Biol., 203, 2018
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6JCE
 | | NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes | | 分子名称: | 29-mer DNA | | 著者 | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T. | | 登録日 | 2019-01-28 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
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2AHO
 | | Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus solfataricus complexed with GDPNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 alpha subunit, ... | | 著者 | Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E. | | 登録日 | 2005-07-28 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Switch of the gamma Subunit in an Archaeal aIF2alphagamma Heterodimer
Structure, 14, 2006
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4MNO
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4MO0
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2PTH
 | | PEPTIDYL-TRNA HYDROLASE FROM ESCHERICHIA COLI | | 分子名称: | PEPTIDYL-TRNA HYDROLASE | | 著者 | Schmitt, E, Mechulam, Y, Fromant, M, Plateau, P, Blanquet, S. | | 登録日 | 1997-03-25 | | 公開日 | 1998-03-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structure at 1.2 A resolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase.
EMBO J., 16, 1997
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2MS9
 | | Solution structure of a G-quadruplex | | 分子名称: | DNA (28-MER) | | 著者 | Chung, W.J, Heddi, B, Schmitt, E, Lim, K.W, Mechulam, Y, Phan, A.T. | | 登録日 | 2014-07-25 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a left-handed DNA G-quadruplex
Proc.Natl.Acad.Sci.USA, 2015
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7D5D
 | | Left-handed G-quadruplex containing one bulge | | 分子名称: | 1xBulge-LHG4motif, POTASSIUM ION, SPERMINE | | 著者 | Das, P, Ngo, K.H, Winnerdy, F.R, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | | 登録日 | 2020-09-25 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Bulges in left-handed G-quadruplexes.
Nucleic Acids Res., 49, 2021
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7D5E
 | | Left-handed G-quadruplex containing two bulges | | 分子名称: | 2xBulge-LHG4motif, POTASSIUM ION, SODIUM ION, ... | | 著者 | Das, P, Maity, A, Ngo, K.H, Winnerdy, F.R, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | | 登録日 | 2020-09-25 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | | 主引用文献 | Bulges in left-handed G-quadruplexes.
Nucleic Acids Res., 49, 2021
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3H97
 | | Structure of a mutant methionyl-tRNA synthetase with modified specificity | | 分子名称: | CITRIC ACID, Methionyl-tRNA synthetase, ZINC ION | | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | | 登録日 | 2009-04-30 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol., 394, 2009
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3H9C
 | | Structure of methionyl-tRNA synthetase: crystal form 2 | | 分子名称: | CITRIC ACID, Methionyl-tRNA synthetase, ZINC ION | | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | | 登録日 | 2009-04-30 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol., 394, 2009
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7DFY
 | | Novel motif for left-handed G-quadruplex formation | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2xMotif2, POTASSIUM ION, ... | | 著者 | Das, P, Winnerdy, F.R, Maity, A, Mechulam, Y, Phan, A.T. | | 登録日 | 2020-11-10 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | A novel minimal motif for left-handed G-quadruplex formation.
Chem.Commun.(Camb.), 57, 2021
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3H9B
 | | Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with azidonorleucine | | 分子名称: | 6-azido-L-norleucine, CITRIC ACID, Methionyl-tRNA synthetase, ... | | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | | 登録日 | 2009-04-30 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol., 394, 2009
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7D5F
 | | Left-handed G-quadruplex containing 3 bulges | | 分子名称: | 3xBulge-LHG4motif | | 著者 | Winnerdy, F.R, Das, P, Ngo, K.H, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | | 登録日 | 2020-09-25 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Bulges in left-handed G-quadruplexes.
Nucleic Acids Res., 49, 2021
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3H99
 | | Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with methionine | | 分子名称: | CITRIC ACID, METHIONINE, Methionyl-tRNA synthetase, ... | | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | | 登録日 | 2009-04-30 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity.
J.Mol.Biol., 394, 2009
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1P7P
 | | Methionyl-tRNA synthetase from Escherichia coli complexed with methionine phosphonate | | 分子名称: | (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID, Methionyl-tRNA synthetase, ZINC ION | | 著者 | Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S. | | 登録日 | 2003-05-05 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
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