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PDB: 183 results

6EAK
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CRYSTAL STRUCTURE OF FUSION INHIBITOR JNJ-2408068 IN COMPLEX WITH HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN ESCAPE VARIANT T400A STABILIZED IN THE PREFUSION STATE
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol, Fusion glycoprotein F0, ...
Authors:Battles, M.B, McLellan, J.S.
Deposit date:2018-08-03
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
6EAE
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BU of 6eae by Molmil
CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT L141W STABILIZED IN THE PREFUSION STATE
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fusion glycoprotein F0, SULFATE ION
Authors:Battles, M.B, McLellan, J.S.
Deposit date:2018-08-03
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
6EAJ
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BU of 6eaj by Molmil
CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT T400A STABILIZED IN THE PREFUSION STATE
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, D(-)-TARTARIC ACID, Fusion glycoprotein F0, ...
Authors:Battles, M.B, McLellan, J.S.
Deposit date:2018-08-03
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
6EAI
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BU of 6eai by Molmil
CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT S398L STABILIZED IN THE PREFUSION STATE
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, D(-)-TARTARIC ACID, ...
Authors:Battles, M.B, McLellan, J.S.
Deposit date:2018-08-03
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance
To be published
7RW6
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BU of 7rw6 by Molmil
BORF2-APOBEC3Bctd Complex
Descriptor: DNA dC->dU-editing enzyme APOBEC-3B, Maltose/maltodextrin-binding periplasmic protein,Ribonucleoside-diphosphate reductase large subunit, ZINC ION
Authors:Shaban, N.M, Yan, R, Shi, K, McLellan, J.S, Yu, Z, Harris, R.S.
Deposit date:2021-08-19
Release date:2022-04-27
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.
Sci Adv, 8, 2022
7S3M
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BU of 7s3m by Molmil
MERS-CoV S stem helix peptide bound to Fab22
Descriptor: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
8CW9
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BU of 8cw9 by Molmil
Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-61026 heavy, ADI-61026 light, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.
Immunity, 55, 2022
8DF1
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BU of 8df1 by Molmil
Chi3l1 bound by antibody C59
Descriptor: C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2022-06-21
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Antib Ther, 6, 2023
8DCN
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BU of 8dcn by Molmil
Crystal structure of Clostridioides difficile binary toxin CDTb D4 fragment in complex with BINTOXB/9 Fab
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/9 Fab heavy chain, BINTOXB/9 Fab light chain
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-06-16
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-06-16
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
3ONY
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BU of 3ony by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with Fucose
Descriptor: 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-08-30
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3ONU
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BU of 3onu by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026
Descriptor: 1,2-ETHANEDIOL, Capsid protein
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-08-30
Release date:2011-05-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3PA1
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BU of 3pa1 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type A
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-10-18
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3Q3A
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BU of 3q3a by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (triglycan)
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-12-21
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q6Q
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BU of 3q6q by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lea
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2011-01-03
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q38
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BU of 3q38 by Molmil
Crystal structure of P domain from norwalk virus strain vietnam 026 in complex with HBGA type B (triglycan)
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-12-21
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3R6J
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BU of 3r6j by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999
Descriptor: 1,2-ETHANEDIOL, VP1 protein
Authors:Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
Deposit date:2011-03-21
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3R0M
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BU of 3r0m by Molmil
Crystal structure of anti-HIV llama VHH antibody A12
Descriptor: Llama VHH A12, SULFATE ION
Authors:Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
Deposit date:2011-03-08
Release date:2012-03-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
3Q39
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BU of 3q39 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (diglycan)
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-12-21
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q6R
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BU of 3q6r by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lex
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
Authors:Hansman, G.S, Biertumpfel, C, McLellan, J.S, Chen, L, Georgiev, I, Katayama, K, Kwong, P.D.
Deposit date:2011-01-03
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3RJQ
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BU of 3rjq by Molmil
Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
Authors:Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
Deposit date:2011-04-15
Release date:2012-05-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3R6K
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BU of 3r6k by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999 in complex with HBGA type B (triglycan)
Descriptor: 1,2-ETHANEDIOL, VP1 protein, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose
Authors:Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
Deposit date:2011-03-21
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3RY8
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BU of 3ry8 by Molmil
Structural basis for norovirus inhibition and fucose mimicry by citrate
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Capsid protein
Authors:Hansman, G.S, McLellan, J.S, Kwong, P.D.
Deposit date:2011-05-11
Release date:2011-11-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for norovirus inhibition and fucose mimicry by citrate.
J.Virol., 86, 2012
3PA2
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BU of 3pa2 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type Ley
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-10-18
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
1YHM
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BU of 1yhm by Molmil
Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate, Isopentenyl diphosphate and mg+2
Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, MAGNESIUM ION, ...
Authors:Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
Deposit date:2005-01-09
Release date:2005-12-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005

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