3TCL
| Crystal Structure of HIV-1 Neutralizing Antibody CH04 | Descriptor: | CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE | Authors: | Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D. | Deposit date: | 2011-08-09 | Release date: | 2011-11-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.906 Å) | Cite: | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
|
|
3U46
| CH04H/CH02L P212121 | Descriptor: | CH02 Light chain Fab, CH04 Heavy chain Fab | Authors: | Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D. | Deposit date: | 2011-10-07 | Release date: | 2011-11-30 | Last modified: | 2011-12-21 | Method: | X-RAY DIFFRACTION (2.906 Å) | Cite: | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
|
|
7UOP
| |
7UP9
| Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2D3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2D3 heavy chain, ... | Authors: | Byrne, P.O, McLellan, J.S. | Deposit date: | 2022-04-14 | Release date: | 2023-03-29 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein. Nat Commun, 14, 2023
|
|
7UPD
| |
7UPA
| |
7UPB
| |
7UPK
| |
7USM
| Integrin alphaM/beta2 ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Goldsmith, J.A, McLellan, J.S. | Deposit date: | 2022-04-25 | Release date: | 2022-08-17 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin. Cell Rep, 40, 2022
|
|
7USL
| Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Goldsmith, J.A, McLellan, J.S. | Deposit date: | 2022-04-25 | Release date: | 2022-08-17 | Last modified: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin. Cell Rep, 40, 2022
|
|
1YHL
| Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2 | Descriptor: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M. | Deposit date: | 2005-01-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. Proteins, 62, 2005
|
|
1YHK
| Trypanosoma cruzi farnesyl diphosphate synthase | Descriptor: | SULFATE ION, farnesyl pyrophosphate synthase | Authors: | Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M. | Deposit date: | 2005-01-09 | Release date: | 2005-12-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. Proteins, 62, 2005
|
|
1YHM
| Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate, Isopentenyl diphosphate and mg+2 | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, MAGNESIUM ION, ... | Authors: | Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M. | Deposit date: | 2005-01-09 | Release date: | 2005-12-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design. Proteins, 62, 2005
|
|
5W24
| Crystal Structure of 5C4 Fab | Descriptor: | (R,R)-2,3-BUTANEDIOL, 5C4 Fab Heavy Chain, 5C4 Fab Light Chain | Authors: | Battles, M.B, McLellan, J.S, Taher, N.M. | Deposit date: | 2017-06-05 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein. Nat Commun, 8, 2017
|
|
4ZYP
| Crystal Structure of Motavizumab and Quaternary-Specific RSV-Neutralizing Human Antibody AM14 in Complex with Prefusion RSV F Glycoprotein | Descriptor: | AM14 antibody Fab heavy chain, AM14 antibody light chain, Fusion glycoprotein F0,Fibritin, ... | Authors: | Gilman, M.S.A, McLellan, J.S. | Deposit date: | 2015-05-21 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein. Plos Pathog., 11, 2015
|
|
4ZYK
| Crystal Structure of Quaternary-Specific RSV-Neutralizing Human Antibody AM14 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, AM14 Fab heavy chain, ... | Authors: | Gilman, M.S.A, McLellan, J.S. | Deposit date: | 2015-05-21 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein. Plos Pathog., 11, 2015
|
|
6OE5
| |
8DF1
| Chi3l1 bound by antibody C59 | Descriptor: | C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ... | Authors: | Wrapp, D, McLellan, J.S. | Deposit date: | 2022-06-21 | Release date: | 2023-03-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice. Antib Ther, 6, 2023
|
|
8DCN
| |
8DCM
| |
6PXG
| |
6PXH
| Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIHYDROFOLIC ACID, ... | Authors: | Wang, N, McLellan, J.S. | Deposit date: | 2019-07-26 | Release date: | 2019-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD. Cell Rep, 28, 2019
|
|
6PZK
| |
8CW9
| |
8DMJ
| |