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PDB: 183 件

3TCL
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Crystal Structure of HIV-1 Neutralizing Antibody CH04
分子名称: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
著者Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D.
登録日2011-08-09
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U46
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CH04H/CH02L P212121
分子名称: CH02 Light chain Fab, CH04 Heavy chain Fab
著者Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2011-12-21
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
7UOP
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 4H3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4H3 heavy chain, Fab 4H3 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-13
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UP9
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2D3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2D3 heavy chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPD
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2B12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2B12 heavy chain, Fab 2B12 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPA
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1H8 heavy chain, Fab 1H8 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPB
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1H1 heavy chain, Fab 1H1 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPK
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1A9
分子名称: Fab 1A9 heavy chain, Fab 1A9 light chain, Fusion glycoprotein F0
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-15
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7USM
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Integrin alphaM/beta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7USL
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Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
1YHL
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Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2
分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ...
著者Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
登録日2005-01-09
公開日2005-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005
1YHK
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Trypanosoma cruzi farnesyl diphosphate synthase
分子名称: SULFATE ION, farnesyl pyrophosphate synthase
著者Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
登録日2005-01-09
公開日2005-12-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005
1YHM
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Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate, Isopentenyl diphosphate and mg+2
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, MAGNESIUM ION, ...
著者Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
登録日2005-01-09
公開日2005-12-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005
5W24
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BU of 5w24 by Molmil
Crystal Structure of 5C4 Fab
分子名称: (R,R)-2,3-BUTANEDIOL, 5C4 Fab Heavy Chain, 5C4 Fab Light Chain
著者Battles, M.B, McLellan, J.S, Taher, N.M.
登録日2017-06-05
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
4ZYP
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Crystal Structure of Motavizumab and Quaternary-Specific RSV-Neutralizing Human Antibody AM14 in Complex with Prefusion RSV F Glycoprotein
分子名称: AM14 antibody Fab heavy chain, AM14 antibody light chain, Fusion glycoprotein F0,Fibritin, ...
著者Gilman, M.S.A, McLellan, J.S.
登録日2015-05-21
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
Plos Pathog., 11, 2015
4ZYK
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BU of 4zyk by Molmil
Crystal Structure of Quaternary-Specific RSV-Neutralizing Human Antibody AM14
分子名称: 1,2-ETHANEDIOL, ACETATE ION, AM14 Fab heavy chain, ...
著者Gilman, M.S.A, McLellan, J.S.
登録日2015-05-21
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
Plos Pathog., 11, 2015
6OE5
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BU of 6oe5 by Molmil
Splayed open prefusion RSV F captured by CR9501 and motavizumab Fabs
分子名称: CR9501 Fab Heavy Chain, CR9501 Fab Light Chain, Fusion glycoprotein F0,Fibritin, ...
著者Gilman, M.S.A, McLellan, J.S.
登録日2019-03-27
公開日2019-04-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Transient opening of trimeric prefusion RSV F proteins.
Nat Commun, 10, 2019
8DF1
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Chi3l1 bound by antibody C59
分子名称: C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ...
著者Wrapp, D, McLellan, J.S.
登録日2022-06-21
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Antib Ther, 6, 2023
8DCN
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Crystal structure of Clostridioides difficile binary toxin CDTb D4 fragment in complex with BINTOXB/9 Fab
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/9 Fab heavy chain, BINTOXB/9 Fab light chain
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
6PXG
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BU of 6pxg by Molmil
Crystal Structure of MERS-CoV neutralizing antibody G2 Fab
分子名称: G2 Fab Heavy Chain, G2 Fab Light chain
著者Wang, N, McLellan, J.S.
登録日2019-07-26
公開日2019-09-25
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6PXH
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Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIHYDROFOLIC ACID, ...
著者Wang, N, McLellan, J.S.
登録日2019-07-26
公開日2019-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6PZK
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Cryo-EM Structure of the Respiratory Syncytial Virus Polymerase (L) Protein Bound by the Tetrameric Phosphoprotein (P)
分子名称: Phosphoprotein, RNA-directed RNA polymerase L
著者Gilman, M.S.A, McLellan, J.S.
登録日2019-08-01
公開日2019-09-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the Respiratory Syncytial Virus Polymerase Complex.
Cell, 179, 2019
8CW9
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BU of 8cw9 by Molmil
Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-61026 heavy, ADI-61026 light, ...
著者Hsieh, C.-L, McLellan, J.S.
登録日2022-05-18
公開日2022-08-10
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.
Immunity, 55, 2022
8DMJ
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BU of 8dmj by Molmil
Postfusion Nipah virus fusion protein in complex with Fab 1H1
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F1, antibody 1H1 heavy chain, antibody 1H1 light chain
著者Byrne, P.O, Blade, E.G, McLellan, J.S.
登録日2022-07-08
公開日2023-07-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Postfusion Nipah virus fusion protein in complex with Fab 1H1
To Be Published

224004

件を2024-08-21に公開中

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