3DI2
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3DI3
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2KMN
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2KO8
| The Structure of Anti-TRAP | Descriptor: | Tryptophan RNA-binding attenuator protein inhibitory protein, ZINC ION | Authors: | McElroy, C.A, Gollnick, P, Foster, M.P. | Deposit date: | 2009-09-12 | Release date: | 2010-09-22 | Last modified: | 2020-02-26 | Method: | SOLUTION NMR | Cite: | Solution Structure of the B. subtilis Anti-TRAP trimer and its Interaction with TRAP To be Published
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3UP1
| Crystal structure of the unliganded human interleukin-7 receptor extracellular domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | McElroy, C.A, Holland, P.J, Walsh, S.T.R. | Deposit date: | 2011-11-17 | Release date: | 2012-02-08 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural reorganization of the interleukin-7 signaling complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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1OQK
| Structure of Mth11: A homologue of human RNase P protein Rpp29 | Descriptor: | conserved protein MTH11 | Authors: | Boomershine, W.P, McElroy, C.A, Tsai, H, Gopalan, V, Foster, M.P. | Deposit date: | 2003-03-10 | Release date: | 2004-01-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P. Proc.Natl.Acad.Sci.Usa, 100, 2003
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7MVS
| DNA gyrase complexed with uncleaved DNA and Compound 7 to 2.6A resolution | Descriptor: | (1S)-2-[(2r,5S)-5-{[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]amino}-1,3-dioxan-2-yl]-1-(3-fluoro-6-methoxyquinolin-4-yl)ethan-1-ol, CHLORIDE ION, DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... | Authors: | Ratigan, S.C, McElroy, C.A. | Deposit date: | 2021-05-15 | Release date: | 2021-10-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.60137153 Å) | Cite: | Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA. J.Med.Chem., 64, 2021
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