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PDB: 6 件

3DEY
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BU of 3dey by Molmil
Crystal structure of 17beta-HSD1 with DHT in normal and reverse orientation.
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL
著者Mazumdar, M.
登録日2008-06-10
公開日2009-09-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献17beta-HSD1 stimulates breast cancer by DHT inactivation in addition to estradiol production.
To be Published
3HB5
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BU of 3hb5 by Molmil
Binary and ternary crystal structures of a novel inhibitor of 17 beta-HSD type 1: a lead compound for breast cancer therapy
分子名称: 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide, Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Mazumdar, M, Lin, S.-X.
登録日2009-05-04
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy.
Biochem.J., 424, 2009
3HB4
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BU of 3hb4 by Molmil
17beta-hydroxysteroid dehydrogenase type1 complexed with E2B
分子名称: 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide, Estradiol 17-beta-dehydrogenase 1
著者Mazumdar, M, Fournier, D, Zhu, D.-W, Cadot, C, Poirier, D, Lin, S.-X.
登録日2009-05-04
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy.
Biochem.J., 424, 2009
3KM0
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BU of 3km0 by Molmil
17betaHSD1 in complex with 3beta-diol
分子名称: 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL, Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Mazumdar, M, Lin, S.-X.
登録日2009-11-09
公開日2010-11-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of sex-steroid translation
To be Published
3KLM
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BU of 3klm by Molmil
17beta-HSD1 in complex with DHT
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL
著者Mazumdar, M.
登録日2009-11-08
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.
Mol.Endocrinol., 24, 2010
3KLP
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BU of 3klp by Molmil
17beta-HSD1 in complex with A-diol
分子名称: (3alpha,8alpha,17beta)-androst-5-ene-3,17-diol, Estradiol 17-beta-dehydrogenase 1
著者Mazumdar, M, Lin, S.-X.
登録日2009-11-08
公開日2010-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis of sex-steroids: their translational activity
To be Published

221716

件を2024-06-26に公開中

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