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PDB: 1 results

Ras guanine nucleotide exchange factor SOS2 (Rem-cdc25), with surface mutations
Descriptor:	Son of sevenless homolog 2
Authors:	Hillig, R.C, Moosmayer, D, Mastouri, J.
Deposit date:	2017-09-19
Release date:	2019-02-06
Last modified:	2024-01-17
Method:	X-RAY DIFFRACTION (2.72 Å)
Cite:	Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019

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PDB entries from 2024-04-24