6ZQB
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![BU of 6zqb by Molmil](/molmil-images/mine/6zqb) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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1JFU
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![BU of 1jfu by Molmil](/molmil-images/mine/1jfu) | CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF TLPA FROM BRADYRHIZOBIUM JAPONICUM | 分子名称: | THIOL:DISULFIDE INTERCHANGE PROTEIN TLPA | 著者 | Capitani, G, Rossmann, R, Sargent, D.F, Gruetter, M.G, Richmond, T.J, Hennecke, H. | 登録日 | 2001-06-22 | 公開日 | 2001-09-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the soluble domain of a membrane-anchored thioredoxin-like protein from Bradyrhizobium japonicum reveals unusual properties. J.Mol.Biol., 311, 2001
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3MSK
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![BU of 3msk by Molmil](/molmil-images/mine/3msk) | Fragment Based Discovery and Optimisation of BACE-1 Inhibitors | 分子名称: | 4-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-cyclohexyl-N-methylbutanamide, Beta-secretase 1, GLYCEROL, ... | 著者 | Smith, M.A, Madden, J.M, Barker, J, Godemann, R, Kraemer, J, Hallett, D. | 登録日 | 2010-04-29 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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6Q6F
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![BU of 6q6f by Molmil](/molmil-images/mine/6q6f) | Crystal structure of IDH1 R132H in complex with HMS101 | 分子名称: | (2~{R})-2-[2-[(3~{R})-3-(4-fluorophenyl)pyrrolidin-1-yl]ethyl]-1,4-dimethyl-piperazine, Isocitrate dehydrogenase [NADP] cytoplasmic | 著者 | Chaturvedi, A, Goparaju, R, Gupta, C, Kluenemann, T, Araujo Cruz, M.M, Kloos, A, Goerlich, K, Schottmann, R, Struys, E.A, Ganser, A, Preller, M, Heuser, M. | 登録日 | 2018-12-10 | 公開日 | 2019-10-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site. Leukemia, 34, 2020
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7AAV
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![BU of 7aav by Molmil](/molmil-images/mine/7aav) | Human pre-Bact-2 spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-04 | 公開日 | 2020-12-09 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7ABF
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![BU of 7abf by Molmil](/molmil-images/mine/7abf) | Human pre-Bact-1 spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-09 | 最終更新日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7ABG
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![BU of 7abg by Molmil](/molmil-images/mine/7abg) | Human pre-Bact-1 spliceosome | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | 登録日 | 2020-09-07 | 公開日 | 2020-12-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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6TMF
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![BU of 6tmf by Molmil](/molmil-images/mine/6tmf) | Structure of an archaeal ABCE1-bound ribosomal post-splitting complex | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Kratzat, H, Becker, T, Tampe, R, Beckmann, R. | 登録日 | 2019-12-04 | 公開日 | 2020-02-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex. Embo J., 39, 2020
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2OG4
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![BU of 2og4 by Molmil](/molmil-images/mine/2og4) | |
3MSJ
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![BU of 3msj by Molmil](/molmil-images/mine/3msj) | Structure of bace (beta secretase) in complex with inhibitor | 分子名称: | 3-(2-amino-5-chloro-1H-benzimidazol-1-yl)propan-1-ol, BETA-SECRETASE 1, GLYCEROL | 著者 | Madden, J, Kramer, J, Smith, M.A, Barker, J, Godemann, R. | 登録日 | 2010-04-29 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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1GK7
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![BU of 1gk7 by Molmil](/molmil-images/mine/1gk7) | HUMAN VIMENTIN COIL 1A FRAGMENT (1A) | 分子名称: | SULFATE ION, VIMENTIN | 著者 | Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P. | 登録日 | 2001-08-08 | 公開日 | 2002-03-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly. Embo J., 21, 2002
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2QPZ
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![BU of 2qpz by Molmil](/molmil-images/mine/2qpz) | Naphthalene 1,2-dioxygenase Rieske ferredoxin | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, Naphthalene 1,2-dioxygenase system ferredoxin subunit | 著者 | Brown, E.N, Ramaswamy, S, Karlsson, A, Friemann, R, Parales, J.V, Parales, R, Gibson, D.T. | 登録日 | 2007-07-25 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Determining Rieske cluster reduction potentials. J.Biol.Inorg.Chem., 13, 2008
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7A1G
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![BU of 7a1g by Molmil](/molmil-images/mine/7a1g) | Structure of a crosslinked yeast ABCE1-bound 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Mackens-Kiani, T, Kratzat, H, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-08-13 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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7AJU
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![BU of 7aju by Molmil](/molmil-images/mine/7aju) | Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | 登録日 | 2020-09-29 | 公開日 | 2020-12-30 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
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3ELV
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![BU of 3elv by Molmil](/molmil-images/mine/3elv) | Crystal Structure of Full-Length Yeast Pml1p | 分子名称: | Pre-mRNA leakage protein 1, SULFATE ION | 著者 | Trowitzsch, S, Weber, G, L hrmann, R, Wahl, M.C. | 登録日 | 2008-09-23 | 公開日 | 2009-02-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex. J.Mol.Biol., 385, 2009
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2MK0
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![BU of 2mk0 by Molmil](/molmil-images/mine/2mk0) | Structure of the PSCD4-domain of the cell wall protein pleuralin-1 from the diatom Cylindrotheca fusiformis | 分子名称: | HEP200 protein | 著者 | De Sanctis, S, Wenzler, M, Kroeger, N, Malloni, W.M, Sumper, M, Deutzmann, R, Zadravec, P, Brunner, E, Kremer, W, Kalbitzer, S.H.R. | 登録日 | 2014-01-22 | 公開日 | 2015-02-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | PSCD Domains of Pleuralin-1 from the Diatom Cylindrotheca fusiformis: NMR Structures and Interactions with Other Biosilica-Associated Proteins. Structure, 24, 2016
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6ZQE
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![BU of 6zqe by Molmil](/molmil-images/mine/6zqe) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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6ZXD
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![BU of 6zxd by Molmil](/molmil-images/mine/6zxd) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1 | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | 登録日 | 2020-07-29 | 公開日 | 2020-12-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
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6ZU9
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![BU of 6zu9 by Molmil](/molmil-images/mine/6zu9) | Structure of a yeast ABCE1-bound 48S initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-22 | 公開日 | 2020-10-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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6ZXF
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![BU of 6zxf by Molmil](/molmil-images/mine/6zxf) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State G | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | 登録日 | 2020-07-29 | 公開日 | 2020-12-02 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
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6ZQF
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![BU of 6zqf by Molmil](/molmil-images/mine/6zqf) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B (Poly-Ala) | 分子名称: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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6ZQG
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![BU of 6zqg by Molmil](/molmil-images/mine/6zqg) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-C | 分子名称: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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6ZVJ
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![BU of 6zvj by Molmil](/molmil-images/mine/6zvj) | Structure of a human ABCE1-bound 43S pre-initiation complex - State II | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-24 | 公開日 | 2020-10-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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6ZQD
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![BU of 6zqd by Molmil](/molmil-images/mine/6zqd) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1 | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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7A09
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![BU of 7a09 by Molmil](/molmil-images/mine/7a09) | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-08-07 | 公開日 | 2020-10-14 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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