5LL6
 
 | | Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Heuer, A, Gerovac, M, Schmidt, C, Trowitzsch, S, Preis, A, Koetter, P, Berninghausen, O, Becker, T, Beckmann, R, Tampe, R. | | 登録日 | 2016-07-26 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
Nat. Struct. Mol. Biol., 24, 2017
|
|
5MVD
 | | Crystal structure of potent human Dihydroorotate Dehydrogenase inhibitors based on hydroxylated azole scaffolds | | 分子名称: | 1,5-dimethyl-3-oxidanyl-~{N}-[2,3,5,6-tetrakis(fluoranyl)-4-phenyl-phenyl]pyrazole-4-carboxamide, ACETATE ION, CHLORIDE ION, ... | | 著者 | Goyal, P, Andersson, M, Moritzer, A.C, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S, Lolli, M, Friemann, R. | | 登録日 | 2017-01-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds.
Eur J Med Chem, 129, 2017
|
|
3IZQ
 | | Structure of the Dom34-Hbs1-GDPNP complex bound to a translating ribosome | | 分子名称: | Elongation factor 1 alpha-like protein, Protein DOM34 | | 著者 | Becker, T, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Sieber, H, Abdel Motaal, B, Mielke, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2010-11-30 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | | 主引用文献 | Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome.
Nat.Struct.Mol.Biol., 18, 2011
|
|
8C83
 | | Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ... | | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2023-01-18 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
|
|
8CAH
 | | Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2023-01-24 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
|
|
4CRM
 | | Cryo-EM of a pre-recycling complex with eRF1 and ABCE1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1, ... | | 著者 | Preis, A, Heuer, A, Barrio-Garcia, C, Hauser, A, Eyler, D, Berninghausen, O, Green, R, Becker, T, Beckmann, R. | | 登録日 | 2014-02-28 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.75 Å) | | 主引用文献 | Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing Erf1-Erf3 or Erf1-Abce1.
Cell Rep., 8, 2014
|
|
8CAS
 | | Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2023-01-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
|
|
8CBJ
 | | Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex | | 分子名称: | 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... | | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2023-01-25 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
|
|
6FF7
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
|
|
5OQL
 | | Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum | | 分子名称: | 35S rRNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ... | | 著者 | Cheng, J, Kellner, N, Berninghausen, O, Hurt, E, Beckmann, R. | | 登録日 | 2017-08-12 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017
|
|
5O2R
 | | Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N. | | 登録日 | 2017-05-22 | | 公開日 | 2017-07-26 | | 最終更新日 | 2019-02-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
Nat. Struct. Mol. Biol., 24, 2017
|
|
5NJT
 | | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N. | | 登録日 | 2017-03-29 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.
EMBO J., 36, 2017
|
|
6FF4
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
|
|
5MC6
 | | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. | | 登録日 | 2016-11-09 | | 公開日 | 2017-01-18 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
|
|
4CRN
 | | Cryo-EM of a pretermination complex with eRF1 and eRF3 | | 分子名称: | ERF1 IN RIBOSOME-BOUND ERF1-ERF3-GDPNP COMPLEX, ERF3 IN RIBOSOME BOUND ERF1-ERF3-GDPNP COMPLEX, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Preis, A, Heuer, A, Barrio-Garcia, C, Hauser, A, Eyler, D, Berninghausen, O, Green, R, Becker, T, Beckmann, R. | | 登録日 | 2014-02-28 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing Erf1-Erf3 or Erf1-Abce1.
Cell Rep., 8, 2014
|
|
5MGP
 | | Structural basis for ArfA-RF2 mediated translation termination on stop-codon lacking mRNAs | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Huter, P, Mueller, C, Beckert, B, Arenz, S, Berninghausen, O, Beckmann, R, Wilson, N.D. | | 登録日 | 2016-11-21 | | 公開日 | 2016-12-14 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons.
Nature, 541, 2017
|
|
6EM1
 | | State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
|
|
6EM3
 | | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
|
|
6EML
 | | Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae | | 分子名称: | 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | | 著者 | Heuer, A, Thomson, E, Schmidt, C, Berninghausen, O, Becker, T, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-02 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of a late pre-40S ribosomal subunit fromSaccharomyces cerevisiae.
Elife, 6, 2017
|
|
6EM4
 | | State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
|
|
6EM5
 | | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
|
|
8C6J
 | | Human spliceosomal PM5 C* complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Dybkov, O, Kastner, B, Luehrmann, R. | | 登録日 | 2023-01-12 | | 公開日 | 2023-07-12 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
|
|
6G53
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State E | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2018-03-28 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
|
|
6G4S
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State B | | 分子名称: | 40S ribosomal protein S11, 40S ribosomal protein S13, 40S ribosomal protein S14, ... | | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2018-03-28 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
|
|
6G4W
 | | Cryo-EM structure of a late human pre-40S ribosomal subunit - State A | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2018-03-28 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
|
|
