5ML5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ml5 by Molmil](/molmil-images/mine/5ml5) | Human p38alpha MAPK in complex with imidazolyl pyridine inhibitor 11b | Descriptor: | 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-methylsulfanyl-1~{H}-imidazol-5-yl]pyridin-2-yl]propanamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Buehrmann, M, Rauh, D. | Deposit date: | 2016-12-06 | Release date: | 2017-04-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1 delta and Their Structural Relation to p38 alpha MAPK. Molecules, 22, 2017
|
|
3CRU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cru by Molmil](/molmil-images/mine/3cru) | Structural characterization of an engineered allosteric protein | Descriptor: | GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme | Authors: | Sagermann, M, Chapleau, R, DeLorimier, E, Lei, M. | Deposit date: | 2008-04-07 | Release date: | 2009-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
|
|
3CRT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3crt by Molmil](/molmil-images/mine/3crt) | Structural characterization of an engineered allosteric protein | Descriptor: | GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme | Authors: | Sagermann, M, Chapleau, R, DeLorimier, E, Lei, M. | Deposit date: | 2008-04-07 | Release date: | 2009-02-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
|
|
5N6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n6p by Molmil](/molmil-images/mine/5n6p) | AMPA receptor NTD mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | Authors: | Rossmann, M, Krieger, J.M. | Deposit date: | 2017-02-15 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Allosteric communication pathways in glutamate receptor N-terminal domains To Be Published
|
|
1HO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ho8 by Molmil](/molmil-images/mine/1ho8) | |
1HYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hyp by Molmil](/molmil-images/mine/1hyp) | |
2B7X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b7x by Molmil](/molmil-images/mine/2b7x) | |
5LOS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5los by Molmil](/molmil-images/mine/5los) | Piriformospora indica PIIN_05872 | Descriptor: | PIIN_05872, SULFATE ION, ZINC ION | Authors: | Hartmann, M.D, Albrecht, R, Martin, J, Lupas, A.N. | Deposit date: | 2016-08-09 | Release date: | 2018-05-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A secreted fungal histidine- and alanine-rich protein regulates metal ion homeostasis and oxidative stress. New Phytol., 227, 2020
|
|
1JTN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jtn by Molmil](/molmil-images/mine/1jtn) | |
1JTM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jtm by Molmil](/molmil-images/mine/1jtm) | |
2UWC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uwc by Molmil](/molmil-images/mine/2uwc) | Crystal structure of Nasturtium xyloglucan hydrolase isoform NXG2 | Descriptor: | CELLULASE | Authors: | Baumann, M.J, Eklof, J.M, Michel, G, Kallas, A, Teeri, T.T, Brumer, H, Czjzek, M. | Deposit date: | 2007-03-20 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Evidence for the Evolution of Xyloglucanase Activity from Xyloglucan Endo-Transglycosylases: Biological Implications for Cell Wall Metabolism. Plant Cell, 19, 2007
|
|
1JQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jqu by Molmil](/molmil-images/mine/1jqu) | |
6NN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nn3 by Molmil](/molmil-images/mine/6nn3) | Structure of parvovirus B19 decorated with Fab molecules from a human antibody | Descriptor: | Fab monoclonal antibody 860-55D, heavy chain, light chain, ... | Authors: | Rossmann, M.G, Sun, Y, Klose, T, Liu, Y. | Deposit date: | 2019-01-14 | Release date: | 2019-02-13 | Last modified: | 2020-03-04 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody. J. Virol., 93, 2019
|
|
2VBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vbu by Molmil](/molmil-images/mine/2vbu) | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | Deposit date: | 2007-09-16 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels. Structure, 15, 2007
|
|
2VBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vbv by Molmil](/molmil-images/mine/2vbv) | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and FMN | Descriptor: | CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... | Authors: | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | Deposit date: | 2007-09-16 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels. Structure, 15, 2007
|
|
2VBS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vbs by Molmil](/molmil-images/mine/2vbs) | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with PO4 | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RIBOFLAVIN KINASE, ... | Authors: | Hartmann, M.D, Djuranovic, S, Ammelburg, M, Martin, J, Lupas, A.N, Zeth, K. | Deposit date: | 2007-09-16 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels. Structure, 15, 2007
|
|
7ZH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zh8 by Molmil](/molmil-images/mine/7zh8) | DYRK1a in Complex with a Bromo-Triazolo-Pyridine | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | Authors: | Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M. | Deposit date: | 2022-04-05 | Release date: | 2022-11-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes. J.Med.Chem., 65, 2022
|
|
2VBT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vbt by Molmil](/molmil-images/mine/2vbt) | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and PO4 | Descriptor: | CYTIDINE-5'-DIPHOSPHATE, PHOSPHATE ION, RIBOFLAVIN KINASE, ... | Authors: | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | Deposit date: | 2007-09-16 | Release date: | 2007-11-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels. Structure, 15, 2007
|
|
1LLH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1llh by Molmil](/molmil-images/mine/1llh) | ARE CARBOXY TERMINII OF HELICES CODED BY THE LOCAL SEQUENCE OR BY TERTIARY STRUCTURE CONTACTS | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | Authors: | Sagermann, M, Martensson, L.-G, Baase, W.A, Matthews, B.W. | Deposit date: | 2002-04-28 | Release date: | 2002-05-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A test of proposed rules for helix capping: Implications for protein design Protein Sci., 11, 2002
|
|
3GFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gfh by Molmil](/molmil-images/mine/3gfh) | |
5NHY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nhy by Molmil](/molmil-images/mine/5nhy) | BAY-707 in complex with MTH1 | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, GLYCEROL, SULFATE ION, ... | Authors: | Ellermann, M, Eheim, A, Giese, A, Bunse, S, Nowak-Reppel, K, Neuhaus, R, Weiske, J, Quanz, M, Glasauer, A, Meyer, H, Queisser, N, Irlbacher, H, Bader, B, Rahm, F, Viklund, J, Andersson, M, Ericsson, U, Ginman, T, Forsblom, R, Lindstrom, J, Silvander, C, Tresaugues, L, Gorjanacz, M. | Deposit date: | 2017-03-22 | Release date: | 2017-07-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target. ACS Chem. Biol., 12, 2017
|
|
2UWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uwb by Molmil](/molmil-images/mine/2uwb) | Crystal structure of the Nasturtium seedling mutant xyloglucanase isoform NXG1-delta-YNIIG | Descriptor: | CELLULASE | Authors: | Baumann, M.J, Eklof, J, Michel, G, Kallasa, A, Teeri, T.T, Brumer, H, Czjzek, M. | Deposit date: | 2007-03-20 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Evidence for the Evolution of Xyloglucanase Activity from Xyloglucan Endo-Transglycosylases: Biological Implications for Cell Wall Metabolism. Plant Cell, 19, 2007
|
|
2WG6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wg6 by Molmil](/molmil-images/mine/2wg6) | Proteasome-Activating Nucleotidase (PAN) N-domain (57-134) from Archaeoglobus fulgidus fused to GCN4, P61A Mutant | Descriptor: | GENERAL CONTROL PROTEIN GCN4, PROTEASOME-ACTIVATING NUCLEOTIDASE | Authors: | Hartmann, M.D, Djuranovic, S, Ursinus, A, Zeth, K, Lupas, A.N. | Deposit date: | 2009-04-15 | Release date: | 2009-04-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Activity of the N-Terminal Substrate Recognition Domains in Proteasomal Atpases. Mol.Cell, 34, 2009
|
|
3ZMF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zmf by Molmil](/molmil-images/mine/3zmf) | Salmonella enterica SadA 303-358 fused to GCN4 adaptors (SadAK2) | Descriptor: | GENERAL CONTROL PROTEIN GCN4, PUTATIVE INNER MEMBRANE PROTEIN | Authors: | Hartmann, M.D, Hernandez Alvarez, B, Albrecht, R, Lupas, A.N. | Deposit date: | 2013-02-08 | Release date: | 2013-02-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A New Expression System for Protein Crystallization Using Trimeric Coiled-Coil Adaptors. Protein Eng.Des.Sel., 21, 2008
|
|
2UWA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uwa by Molmil](/molmil-images/mine/2uwa) | Crystal structure of the Nasturtium seedling xyloglucanase isoform NXG1 | Descriptor: | CELLULASE, GLYCEROL | Authors: | Baumann, M.J, Eklof, J, Michel, G, Kallasa, A, Teeri, T.T, Brumer, H, Czjzek, M. | Deposit date: | 2007-03-19 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Evidence for the Evolution of Xyloglucanase Activity from Xyloglucan Endo-Transglycosylases: Biological Implications for Cell Wall Metabolism. Plant Cell, 19, 2007
|
|