4O51
| Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide | Descriptor: | IDES hinge peptide, QAA-2095-2 heavy chain, QAA-2095-2 light chain | Authors: | Malia, T.J, Luo, J, Teplyakov, A, Gilliland, G.L. | Deposit date: | 2013-12-19 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge. Proteins, 82, 2014
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4O4Y
| Crystal structure of the anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide | Descriptor: | 2095-2 heavy chain, 2095-2 light chain, GLYCEROL, ... | Authors: | Malia, T.J, Teplyakov, A, Luo, J, Gilliland, G.L. | Deposit date: | 2013-12-19 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge. Proteins, 82, 2014
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6XLI
| CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE | Descriptor: | GLYCEROL, PT3 Fab Heavy Chain, PT3 Fab Light Chain, ... | Authors: | Malia, T.J, Teplyakov, A, Luo, J. | Deposit date: | 2020-06-28 | Release date: | 2020-09-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody. J Alzheimers Dis, 77, 2020
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4M6A
| N-Terminal beta-Strand Swapping in a Consensus Derived Alternative Scaffold Driven by Stabilizing Hydrophobic Interactions | Descriptor: | Tencon | Authors: | Luo, J, Teplyakov, A, Obmolova, G, Malia, T.J, Chan, W, Jocobs, S.A, O'neil, K.T, Gilliland, G.L. | Deposit date: | 2013-08-09 | Release date: | 2014-02-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | N-terminal beta-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions. Proteins, 82, 2014
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2K4T
| Solution structure of human VDAC-1 in LDAO micelles | Descriptor: | Voltage-dependent anion-selective channel protein 1 | Authors: | Hiller, S, Garces, R.G, Malia, T.J, Orekhov, V.Y, Colombini, M, Wagner, G. | Deposit date: | 2008-06-17 | Release date: | 2008-09-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science, 321, 2008
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7T86
| Crystal Structure of Fab CR5133 / Phospho-SD Peptide Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab CR5133 Heavy Chain, Antibody Fab CR5133 Light Chain, ... | Authors: | Luo, J, Malia, T.J, Buckley, P.T. | Deposit date: | 2021-12-15 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Cell Host Microbe, 31, 2023
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7T82
| Crystal Structure of LEUKOCIDIN E/CENTYRIN S26/FAB B438 | Descriptor: | Antibody Fab Heavy Chain, Antibody Fab Light Chain, Centyrin S26, ... | Authors: | Luo, J, Malia, T.J, Buckley, P.T. | Deposit date: | 2021-12-15 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Cell Host Microbe, 31, 2023
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7T87
| CRYSTAL STRUCTURE OF LEUKOCIDIN AB/CENTYRIN S17/FAB 214F COMPLEX | Descriptor: | Antibody Fab B214 Heavy Chain, Antibody Fab B214 Light Chain, Centyrin S17, ... | Authors: | Luo, J, Malia, T.J, Buckley, P.T. | Deposit date: | 2021-12-15 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Cell Host Microbe, 31, 2023
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7JGT
| Crystal Structure of FN3tt | Descriptor: | Fibronectin type-III domain-containing protein | Authors: | Luo, J, Malia, T.J. | Deposit date: | 2020-07-19 | Release date: | 2021-07-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium. Proteins, 90, 2022
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5W06
| HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587 | Descriptor: | GLYCEROL, M1587 FAB HEAVY CHAIN, M1587 FAB LIGHT CHAIN, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | Deposit date: | 2017-05-30 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into humanization of anti-tissue factor antibody 10H10. MAbs, 10, 2018
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5W05
| ANTI-TISSUE FACTOR ANTIBODY M59, A HUMANIZED VERSION OF 10H10 | Descriptor: | DI(HYDROXYETHYL)ETHER, M59 FAB HEAVY CHAIN, M59 FAB LIGHT CHAIN | Authors: | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | Deposit date: | 2017-05-30 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural insights into humanization of anti-tissue factor antibody 10H10. MAbs, 10, 2018
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