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PDB: 57 件

7OJX
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E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain synthesis
分子名称: 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), E3 ubiquitin-protein ligase RNF38, Polyubiquitin-B, ...
著者Majorek, K.A, Nakasone, M.A, Huang, D.T.
登録日2021-05-17
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension.
Nat.Chem.Biol., 18, 2022
6EDV
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Structure of a GNAT superfamily acetyltransferase PA3944 in complex with CoA
分子名称: 1,2-ETHANEDIOL, Acetyltransferase PA3944, CALCIUM ION, ...
著者Majorek, K.A, Satchell, K.J.F, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-08-12
公開日2018-12-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro.
Biochemistry, 57, 2018
3PGP
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BU of 3pgp by Molmil
Crystal structure of PA4794 - GNAT superfamily protein in complex with AcCoA
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, CHLORIDE ION, ...
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2010-11-02
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
3OWC
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Crystal structure of GNAT superfamily protein PA2578 from Pseudomonas aeruginosa
分子名称: 1,2-ETHANEDIOL, COENZYME A, Probable acetyltransferase
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2010-09-17
公開日2010-11-03
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of GNAT superfamily protein PA2578 from Pseudomonas aeruginosa
To be Published
5JPH
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Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus in complex with CoA
分子名称: Acetyltransferase SACOL1063, CHLORIDE ION, COENZYME A
著者Majorek, K.A, Osinski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-05-03
公開日2016-06-29
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
5JQ4
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Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus
分子名称: 1,2-ETHANEDIOL, Acetyltransferase SACOL1063, CHLORIDE ION, ...
著者Majorek, K.A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-05-04
公開日2016-06-29
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
3GQS
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Crystal structure of the FHA domain of CT664 protein from Chlamydia trachomatis
分子名称: Adenylate cyclase-like protein, PHOSPHATE ION
著者Majorek, K.A, Cymborowski, M, Chruszcz, M, Evdokimova, E, Egorova, O, Di Leo, R, Zimmerman, M.D, Savchenko, A, Joachimiak, A, Edwards, A.M, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2009-03-24
公開日2009-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the FHA domain of CT664 protein from Chlamydia trachomatis
To be Published
3KKW
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Crystal structure of His-tagged form of PA4794 protein
分子名称: 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2009-11-06
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
Protein Sci., 23, 2014
3HFR
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BU of 3hfr by Molmil
Crystal structure of glutamate racemase from Listeria monocytogenes
分子名称: CHLORIDE ION, Glutamate racemase, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
著者Majorek, K.A, Chruszcz, M, Zimmerman, M.D, Klimecka, M.M, Cymborowski, M, Skarina, T, Onopriyenko, O, Stam, J, Otwinowski, Z, Anderson, W.F, Savchenko, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-05-12
公開日2009-06-09
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of glutamate racemase from Listeria monocytogenes
TO BE PUBLISHED
3ISV
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Crystal structure of glutamate racemase from Listeria monocytogenes in complex with acetate ion
分子名称: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
著者Majorek, K.A, Chruszcz, M, Skarina, T, Onopriyenko, O, Stam, J, Anderson, W.F, Savchenko, A, Bujnicki, J.M, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-08-27
公開日2009-09-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of glutamate racemase from Listeria monocytogenes in complex with acetate ion
To be Published
3IST
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BU of 3ist by Molmil
Crystal structure of glutamate racemase from Listeria monocytogenes in complex with succinic acid
分子名称: CHLORIDE ION, Glutamate racemase, SUCCINIC ACID
著者Majorek, K.A, Chruszcz, M, Skarina, T, Onopriyenko, O, Stam, J, Anderson, W.F, Savchenko, A, Bujnicki, J.M, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-08-27
公開日2009-09-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of glutamate racemase from Listeria monocytogenes in complex with succinic acid
TO BE PUBLISHED
5VDB
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BU of 5vdb by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 3
分子名称: (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794
著者Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2017-04-01
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
5VD6
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6
分子名称: (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name), SULFATE ION, acetyltransferase PA4794
著者Majorek, K.A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2017-04-01
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
3V09
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BU of 3v09 by Molmil
Crystal structure of Rabbit Serum Albumin
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Majorek, K.A, Porebski, P.J, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2011-12-07
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
Mol.Immunol., 52, 2012
3V03
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BU of 3v03 by Molmil
Crystal structure of Bovine Serum Albumin
分子名称: ACETATE ION, CALCIUM ION, Serum albumin
著者Majorek, K.A, Porebski, P.J, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2011-12-07
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
Mol.Immunol., 52, 2012
4L8A
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BU of 4l8a by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, N-(phenylacetyl)glycyl-N~6~-acetyl-L-lysine, ...
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-06-16
公開日2013-07-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
4L89
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with covalently bound CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Maclean, E, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-06-16
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
4KUB
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BU of 4kub by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, GNAT superfamily acetyltransferase PA4794, ...
著者Majorek, K.A, Chruszcz, M, Osinski, T, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-21
公開日2013-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
4OAD
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BU of 4oad by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with chloramphenicol
分子名称: 1,2-ETHANEDIOL, CHLORAMPHENICOL, GNAT superfamily acetyltransferase PA4794, ...
著者Majorek, K.A, Niedzialkowska, E, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2014-01-04
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with chloramphenicol
To be Published
4OAE
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol
分子名称: 1,2-ETHANEDIOL, CHLORAMPHENICOL, GNAT superfamily acetyltransferase PA4794, ...
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2014-01-04
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol
To be Published
4M3S
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BU of 4m3s by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with HEPES
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Xu, X, Cymborowski, M, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-08-06
公開日2013-08-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
Protein Sci., 23, 2014
4JXR
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BU of 4jxr by Molmil
Crystal structure of a GNAT superfamily phosphinothricin acetyltransferase (Pat) from Sinorhizobium meliloti in complex with AcCoA
分子名称: ACETYL COENZYME *A, Acetyltransferase, CITRATE ANION, ...
著者Majorek, K.A, Cooper, D.R, Porebski, P.J, Konina, K, Ahmed, M, Stead, M, Hillerich, B, Seidel, R, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2013-03-28
公開日2013-05-15
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of a GNAT superfamily phosphinothricin acetyltransferase (Pat) from Sinorhizobium meliloti in complex with AcCoA
To be Published
4KLV
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 4-methylumbelliferyl phosphate
分子名称: 1,2-ETHANEDIOL, 4-methylumbelliferyl phosphate, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-07
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013
4KOT
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefotaxime
分子名称: (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid, 1,2-ETHANEDIOL, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-12
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013
4KOX
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin
分子名称: 1,2-ETHANEDIOL, CEPHALOTHIN, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Zimmerman, M.D, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-12
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013

 

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