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PDB: 188 results

6ZWM
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BU of 6zwm by Molmil
cryo-EM structure of human mTOR complex 2, overall refinement
Descriptor: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T.
Deposit date:2020-07-28
Release date:2020-11-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The 3.2- angstrom resolution structure of human mTORC2.
Sci Adv, 6, 2020
6ZPN
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BU of 6zpn by Molmil
Crystal structure of Chaetomium thermophilum Raptor
Descriptor: WD_REPEATS_REGION domain-containing protein
Authors:Imseng, S, Boehm, R, Jakob, R.P, Hall, M.N, Hiller, S, Maier, T.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1.
Mol.Cell, 81, 2021
4C00
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BU of 4c00 by Molmil
Crystal structure of TamA from E. coli
Descriptor: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ACETATE ION, CHLORIDE ION, ...
Authors:Gruss, F, Zaehringer, F, Jakob, R.P, Burmann, B.M, Hiller, S, Maier, T.
Deposit date:2013-07-30
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Structural Basis of Autotransporter Translocation by Tama
Nat.Struct.Mol.Biol., 20, 2013
4CW4
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BU of 4cw4 by Molmil
Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa
Descriptor: BETA-KETOACYL SYNTHASE, CHLORIDE ION, SULFATE ION
Authors:Bukhari, H.S.T, Jakob, R.P, Maier, T.
Deposit date:2014-04-01
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.349 Å)
Cite:Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase.
Structure, 22, 2014
4CSY
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BU of 4csy by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with Sialyl Lewis X
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, E-SELECTIN, ...
Authors:Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T.
Deposit date:2014-03-11
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
1OBB
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BU of 1obb by Molmil
alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+
Descriptor: ALPHA-GLUCOSIDASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Lodge, J.A, Maier, T, Liebl, W, Hoffmann, V, Strater, N.
Deposit date:2003-01-29
Release date:2003-05-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Thermotoga Maritima Alpha-Glucosidase Agla Defines a New Clan of Nad+-Dependent Glycosidases
J.Biol.Chem., 278, 2003
5JIW
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BU of 5jiw by Molmil
Crystal structure of Thermus aquaticus amylomaltase (GH77) in complex with a 34-meric cycloamylose
Descriptor: 1,2-ETHANEDIOL, 4-alpha-glucanotransferase, CARBONATE ION, ...
Authors:Roth, C, Bexten, N, Weizenmann, N, Saenger, T, Maier, T, Zimmermann, W, Straeter, N.
Deposit date:2016-04-22
Release date:2017-01-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Amylose recognition and ring-size determination of amylomaltase.
Sci Adv, 3, 2017
4CW5
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BU of 4cw5 by Molmil
Crystal structure of the enoyl reductase domain of DfnA from Bacillus amyloliquefaciens
Descriptor: DFNA, FLAVIN MONONUCLEOTIDE
Authors:Jakob, R.P, Buhkari, H.S.T, Maier, T.
Deposit date:2014-04-01
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase.
Structure, 22, 2014
7NL6
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BU of 7nl6 by Molmil
Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
Descriptor: CALCIUM ION, DC-SIGN, CRD domain, ...
Authors:Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
Deposit date:2021-02-22
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
7NL7
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BU of 7nl7 by Molmil
Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand
Descriptor: 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ...
Authors:Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T.
Deposit date:2021-02-22
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
7ZSK
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BU of 7zsk by Molmil
K3DAK4 bimodule core of BGC11 from Brevibacillus brevis.
Descriptor: Putative polyketide synthase
Authors:Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T.
Deposit date:2022-05-07
Release date:2022-09-21
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The structure of a polyketide synthase bimodule core.
Sci Adv, 8, 2022
8B7S
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BU of 8b7s by Molmil
Crystal structure of the Chloramphenicol-inactivating oxidoreductase from Novosphingobium sp
Descriptor: Chloramphenicol-inactivating oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Zhang, L, Toplak, M, Saleem-Batcha, R, Hoeing, L, Jakob, R.P, Jehmlich, N, von Bergen, M, Maier, T, Teufel, R.
Deposit date:2022-10-03
Release date:2022-11-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Bacterial Dehydrogenases Facilitate Oxidative Inactivation and Bioremediation of Chloramphenicol.
Chembiochem, 24, 2023
8BP6
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BU of 8bp6 by Molmil
Structure of MHC-class I related molecule MR1 with bound M3Ade
Descriptor: (1R,5S)-8-(9H-purin-6-yl)-2-oxa-8-azabicyclo[3.3.1]nona-3,6-diene-4,6-dicarbaldehyde, Beta-2-microglobulin,Major histocompatibility complex class I-related gene protein
Authors:Berloffa, G, Jakob, R.P, Maier, T.
Deposit date:2022-11-16
Release date:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The carbonyl nucleoside adduct M3Ade stabilizes MR1 and activates MR1-restricted self- and tumor-reactive T cells
To Be Published
8BY8
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BU of 8by8 by Molmil
The cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS-MAT)
Descriptor: Non-reducing polyketide synthase CTB1
Authors:Munoz-Hernandez, H, Maier, T.
Deposit date:2022-12-12
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:The cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS-MAT) at 2.5 Angstroms resolution
To Be Published
8CG5
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BU of 8cg5 by Molmil
The ACP crosslinked to the KS of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS:ACP-MAT)
Descriptor: Acyl carrier protein (ACP) of Non-reducing polyketide synthase CTB1, Non-reducing polyketide synthase CTB1, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-[2-(propanoylamino)ethyl]-beta-alaninamide
Authors:Munoz-Hernandez, H, Tittes, Y.U, Maier, T.
Deposit date:2023-02-03
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:CryoEM structure of ACP crosslinked to KS of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS:ACP-MAT) at 2.7 Angstroms resolution
To Be Published
8CG4
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BU of 8cg4 by Molmil
The organise full-length structure of the fungal non-reducing polyketide synthase (NR-PKS) PksA
Descriptor: Norsolorinic acid synthase
Authors:Munoz-Hernandez, H, Maier, T.
Deposit date:2023-02-03
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:CryoEM structure of the Aspergilus sp. fungal non-reducing polyketide synthase (NR-PKS) PksA at 2.6 Angstroms resolution
To Be Published
5BP4
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BU of 5bp4 by Molmil
Modifying region (DH-ER-KR) of a mycocerosic acid synthase-like (MAS-like) PKS
Descriptor: Mycocerosic acid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Herbst, D.A, Jakob, P.R, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5BP3
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BU of 5bp3 by Molmil
Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 2
Descriptor: 1,2-ETHANEDIOL, Mycocerosic acid synthase-like polyketide synthase
Authors:Herbst, D.A, Jakob, P.R, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5CGB
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BU of 5cgb by Molmil
Crystal structure of FimH in complex with heptyl alpha-D-septanoside
Descriptor: (6R)-1,6-anhydro-2-O-heptyl-6-(hydroxymethyl)-D-galactitol, Protein FimH, SULFATE ION
Authors:Jakob, R.P, Preston, R.P, Zihlmann, P, Fiege, B, Sager, C.P, Vannam, R, Rabbani, S, Zalewski, A, Maier, T, Ernst, B, Peczuh, M.
Deposit date:2015-07-09
Release date:2016-07-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The price of flexibility - a case study on septanoses as pyranose mimetics.
Chem Sci, 9, 2018
5BP1
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BU of 5bp1 by Molmil
Condensing di-domain (KS-AT) of a mycocerosic acid synthase-like (MAS-like) PKS
Descriptor: Mycocerosic acid synthase
Authors:Jakob, R.P, Herbst, D.A, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5BP2
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BU of 5bp2 by Molmil
Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Herbst, D.A, Jakob, P.R, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5I6I
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BU of 5i6i by Molmil
Crystal structure of a dBCCP-variant of Chaetomium thermophilum acetyl-CoA carboxylase
Descriptor: Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein
Authors:Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T.
Deposit date:2016-02-16
Release date:2016-04-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (8.4 Å)
Cite:The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
2MLL
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BU of 2mll by Molmil
MISTLETOE LECTIN I FROM VISCUM ALBUM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (RIBOSOME-INACTIVATING PROTEIN TYPE II)
Authors:Krauspenhaar, R, Eschenburg, S, Perbandt, M, Kornilov, V, Konareva, N, Mikailova, I, Stoeva, S, Wacker, R, Maier, T, Singh, T.P, Mikhailov, A, Voelter, W, Betzel, C.
Deposit date:1999-03-16
Release date:2000-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of mistletoe lectin I from Viscum album.
Biochem.Biophys.Res.Commun., 257, 1999
5IL5
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BU of 5il5 by Molmil
Crystal structure of the dehydratase domain of MlnD from Bacillus amyloliquefaciens
Descriptor: MlnD
Authors:Jakob, R.P, Herbst, D.A, Maier, T.
Deposit date:2016-03-04
Release date:2017-03-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal Structures of Dehydratase Domains from trans-AT Polyketide Biosynthetic Pathways
To Be Published
5J6O
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BU of 5j6o by Molmil
Crystal structure of a trans-AT PKS dehydratase domain of C0ZGQ7 from Brevibacillus brevis
Descriptor: MAGNESIUM ION, Putative polyketide synthase
Authors:Jakob, R.P, Herbst, D.A, Maier, T.
Deposit date:2016-04-05
Release date:2017-05-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.195 Å)
Cite:Crystal Structures of Dehydratase Domains from trans-AT Polyketide Biosynthetic Pathway
To Be Published

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