7QLF
 
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1E0N
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1E0L
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1E0M
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2JOC
 | | Mouse Itch 3rd domain phosphorylated in T30 | | Descriptor: | Itchy E3 ubiquitin protein ligase | | Authors: | Macias, M.J, Shaw, A.Z, Martin-Malpartida, P, Morales, B, Ruiz, L, Ramirez-Espain, X, Yraola, F, Royo, M. | | Deposit date: | 2007-03-06 | | Release date: | 2007-04-17 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | NMR Structural Studies of the ItchWW3 Domain Reveal that Phosphorylation at T30 Inhibits the Interaction with PPxY-Containing Ligands
Structure, 15, 2007
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2JO9
 | | Mouse Itch 3rd WW domain complex with the Epstein-Barr virus latent membrane protein 2A derived peptide EEPPPPYED | | Descriptor: | Itchy E3 ubiquitin protein ligase, Latent membrane protein 2 | | Authors: | Macias, M.J, Shaw, A.Z, Martin-Malpartida, P, Morales, B, Ruiz, L, Ramirez-Espain, X, Yraola, F, Royo, M. | | Deposit date: | 2007-03-01 | | Release date: | 2007-04-17 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | NMR Structural Studies of the ItchWW3 Domain Reveal that Phosphorylation at T30 Inhibits the Interaction with PPxY-Containing Ligands
Structure, 15, 2007
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2LAY
 | | Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide | | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LB2
 | | Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3 | | Descriptor: | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LB1
 | | Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2016-04-27 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LAJ
 | | Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-16 | | Release date: | 2011-07-06 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LTX
 | | Smurf1 WW2 domain in complex with a Smad7 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | Deposit date: | 2012-06-04 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LTY
 | | NEDD4L WW2 domain in complex with a Smad7 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase NEDD4-like, Smad7 derived peptide | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | Deposit date: | 2012-06-04 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LTZ
 | | Smurf2 WW3 domain in complex with a Smad7 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | Deposit date: | 2012-06-04 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2MWA
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2MWF
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2MW9
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2MWE
 | | NMR structure of FBP28 WW2 mutant Y438R, L453A DNDC | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. | | Deposit date: | 2014-11-04 | | Release date: | 2014-12-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2LB0
 | | Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LAX
 | | Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide. | | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LTV
 | | YAP WW2 in complex with a Smad7 derived peptide | | Descriptor: | Smad7 derived peptide, Yorkie homolog | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | Deposit date: | 2012-06-04 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LAZ
 | | Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide | | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LAW
 | | Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide | | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2LTW
 | | YAP WW1 in complex with a Smad7 derived peptide | | Descriptor: | Smad7 derived peptide, Yorkie homolog | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | | Deposit date: | 2012-06-04 | | Release date: | 2012-11-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
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2LB3
 | | Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide | | Descriptor: | Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | | Deposit date: | 2011-03-22 | | Release date: | 2011-07-06 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
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2MWB
 | | FBP28 WW2 mutant W457F | | Descriptor: | Transcription elongation regulator 1 | | Authors: | Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. | | Deposit date: | 2014-11-03 | | Release date: | 2014-12-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements.
Proc.Natl.Acad.Sci.USA, 111, 2014
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