2JO9

Mouse Itch 3rd WW domain complex with the Epstein-Barr virus latent membrane protein 2A derived peptide EEPPPPYED

Summary for 2JO9

• Entry DOI: 10.2210/pdb2jo9/pdb
• Related: 2JOC
• NMR Information: BMRB: 15153
• Descriptor: Itchy E3 ubiquitin protein ligase, Latent membrane protein 2 (2 entities in total)
• Functional Keywords: itch, ww, complex, epstein-barr virus, lmp2a, ligase
• Biological source: Mus musculus (house mouse); More
• Cellular location: Cell membrane (By similarity): Q8C863; Isoform LMP2A: Host cell membrane; Multi- pass membrane protein. Isoform LMP2B: Host endomembrane system; Multi-pass membrane protein: P13285
• Total number of polymer chains: 2
• Total formula weight: 5348.79

Authors

Macias, M.J.,Shaw, A.Z.,Martin-Malpartida, P.,Morales, B.,Ruiz, L.,Ramirez-Espain, X.,Yraola, F.,Royo, M. (deposition date: 2007-03-01, release date: 2007-04-17, Last modification date: 2023-12-20)

• Primary citation: Morales, B.,Ramirez-Espain, X.,Shaw, A.Z.,Martin-Malpartida, P.,Yraola, F.,Sanchez-Tillo, E.,Farrera, C.,Celada, A.,Royo, M.,Macias, M.J.; NMR Structural Studies of the ItchWW3 Domain Reveal that Phosphorylation at T30 Inhibits the Interaction with PPxY-Containing Ligands; Structure, 15:473-483, 2007; PubMed: 17437719; DOI: 10.1016/j.str.2007.03.005

Experimental method

SOLUTION NMR